Zobrazeno 1 - 10
of 68
pro vyhledávání: '"R. Mauritz"'
Autor:
Cécile Vigneau, Binu Porath, Elizabeth K. Dillinger, Saurabh Baheti, Marie C. Hogan, José Ignacio Herrero, Sarah R. Mauritz, Katharina Hopp, Emilie Cornec-Le Gall, Peter C. Harris, Vladimir G. Gainullin, Christina M. Heyer, Vicente E. Torres, Velibor Tasic, Marie Pierre Audrézet, Marie E. Edwards, Terry Watnick, Charles D. Madsen, Arlene B. Chapman, Yannick Le Meur, Frédéric Lavainne, Carly J. Banks, Claude Férec, Jesus M. Banales, Bharathi V. Reddy
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), 2016, 98 (6), pp.1193-1207. ⟨10.1016/j.ajhg.2016.05.004⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2016, 98 (6), pp.1193-1207. ⟨10.1016/j.ajhg.2016.05.004⟩
International audience; Autosomal-dominant polycystic kidney disease (ADPKD) is a common, progressive, adult-onset disease that is an important cause of end-stage renal disease (ESRD), which requires transplantation or dialysis. Mutations in PKD1 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090731092f977a7a75988495eba5ac7c
https://europepmc.org/articles/PMC4908191/
https://europepmc.org/articles/PMC4908191/
Autor:
Jantine L. Westra, Karin A. Oien, R. M. W. Hofstra, W N Keith, Harry Hollema, Michael Schaapveld, J.Th.M. Plukker, R. Mauritz, G.J. Peters, Inge Platteel, Charles H.C.M. Buys
Publikováno v:
Westra, J L, Hollema, H, Schaapveld, M, Platteel, I, Oien, K A, Keith, W N, Mauritz, R, Peters, G J, Buys, C H, Hofstra, R M & Plukker, JT 2005, ' Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase protein expression on survival in adjuvantly treated stage III colon cancer patients ', Annals of Oncology, vol. 16, no. 10, pp. 1646-1653 . https://doi.org/10.1093/annonc/mdi316
Annals of Oncology, 16(10), 1646-1653. Oxford University Press
Annals of Oncology, 16(10), 1646-1653. Oxford University Press
Background: The predictive value of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) expression on long-term survival by influencing 5-fluorouracil (5-FU) effect were determined in primary tumours and node metastases of stage III c
Autor:
Godefridus J. Peters, Sharon Marsh, C.J. van Groeningen, Howard L. McLeod, Herbert M. Pinedo, Kees Smid, Ines J. Beumer, R. Mauritz
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids, 23, 1381-1384. Taylor and Francis Ltd.
Mauritz, R, Beumer, IJ, Marsh, S, McLeod, HL, Smid, K, van Groeningen, C J, Pinedo, H M & Peters, G J 2004, ' Polymorphism of the thymidylate synthase gene and thymidylate synthase levels in colon cancer cell lines and different tissues fo colorectal cancer patients ', Nucleosides, Nucleotides and Nucleic Acids, vol. 23, pp. 1381-1384 . https://doi.org/10.1081/NCN-200027634
Mauritz, R, Beumer, IJ, Marsh, S, McLeod, HL, Smid, K, van Groeningen, C J, Pinedo, H M & Peters, G J 2004, ' Polymorphism of the thymidylate synthase gene and thymidylate synthase levels in colon cancer cell lines and different tissues fo colorectal cancer patients ', Nucleosides, Nucleotides and Nucleic Acids, vol. 23, pp. 1381-1384 . https://doi.org/10.1081/NCN-200027634
In a panel of 18 colon cancer cell lines we found that the thymidylate synthase (TS) genotype was related to TS enzyme activity, but not to TS protein and mRNA levels. In addition, no relation with drug sensitivity was observed. TS genotyping of diff
Autor:
A. Wixmerten, H. Rebscher, Markus Beier, R. Mauritz, P. F. Stähler, M. Baum, C. F. Stähler, M. Müller
Publikováno v:
Biochemical Society Transactions. 30:78-82
Concepts and results are described for the use of a single, but extremely flexible, probing tool to address a wide variety of genomic questions. This is achieved by transforming genomic questions into a software file that is used as the design scheme
Autor:
Ietje Kathmann, Stavit Drori, David G. Priest, Godefridus J. Peters, Yehuda G. Assaraf, Herbert M. Pinedo, Marlene A. Bunni, Jan H. Schornagel, R. Mauritz, Paul Noordhuis, Hannah Sprecher, Gerrit Jansen
Publikováno v:
Journal of Biological Chemistry. 273:30189-30198
CEM/MTX is a subline of human CCRF-CEM leukemia cells which displays >200-fold resistance to methotrexate (MTX) due to defective transport via the reduced folate carrier (RFC). CEM/MTX-low folate (LF) cells, derived by a gradual deprivation of folic
Autor:
Peter C. Harris, John Ouyang, Wen Zhou-CW, Sarah R. Mauritz, Jaime D. Blais, Christina M. Heyer, Ron T. Gansevoort, Arlene B. Chapman, Vicente E. Torres, Sharin Roth, Olivier Devuyst, Yannick Le Meur, Emilie Cornec-Le Gall, Ronald D. Perrone, Frank S. Czerwiec
Publikováno v:
Nephrology Dialysis Transplantation. 31:i174-i174
Autor:
W. Schwabe, Godefridus J. Peters, C.J. van Groeningen, P. Haeusler, D. Behnke, Paul Noordhuis, Kees Smid, Howard L. McLeod, R. Mauritz
Publikováno v:
Mauritz, R, Schwabe, W, Haeusler, P, Noordhuis, P, Smid, K, McLeod, HL, Behnke, D, van Groeningen, C J & Peters, G J 2004, ' Comparison of mRNA expression levels determined with Taq-man and competitive template RT-PCR ', Nucleosides, Nucleotides and Nucleic Acids, vol. 23, pp. 1471-1474 . https://doi.org/10.1081/NCN-200027689
Nucleosides, Nucleotides and Nucleic Acids, 23, 1471-1474. Taylor and Francis Ltd.
Nucleosides, Nucleotides and Nucleic Acids, 23, 1471-1474. Taylor and Francis Ltd.
Two methods for measurement of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) mRNA expression were compared. Although the relative mRNA levels compared to beta-actin measured with competitive template RT-PCR were different from t
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Autor:
M, Beier, M, Baum, H, Rebscher, R, Mauritz, A, Wixmerten, C F, Stähler, M, Müller, P F, Stähler
Publikováno v:
Biochemical Society transactions. 30(2)
Concepts and results are described for the use of a single, but extremely flexible, probing tool to address a wide variety of genomic questions. This is achieved by transforming genomic questions into a software file that is used as the design scheme
Autor:
Jan H. Schornagel, Herbert M. Pinedo, Ietje Kathmann, Marlene A. Bunni, R. Mauritz, Andre Rosowsky, Gerrit Jansen, Yehuda G. Assaraf, David G. Priest, Godefridus J. Peters, Paul Noordhuis, Stavit Drori
Publikováno v:
Biochemical Pharmacology, 63(2), 105-15. Elsevier Inc.
Mauritz, R, Peters, G J, Priest, D G, Assaraf, Y G, Drori, S, Kathmann, I, Noordhuis, P, Bunni, M A, Rosowsky, A, Schornagel, J H, Pinedo, H M & Jansen, G 2002, ' Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis ', Biochemical Pharmacology, vol. 63, no. 2, pp. 105-15 .
Mauritz, R, Peters, G J, Priest, D G, Assaraf, Y G, Drori, S, Kathmann, I, Noordhuis, P, Bunni, M A, Rosowsky, A, Schornagel, J H, Pinedo, H M & Jansen, G 2002, ' Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis ', Biochemical Pharmacology, vol. 63, no. 2, pp. 105-15 .
We determined the mechanisms of resistance of human CCRF-CEM leukemia cells to methotrexate (MTX) vs. those to six novel antifolates: the polyglutamatable thymidylate synthase (TS) inhibitors ZD1694, multitargeted antifolate, pemetrexed, ALIMTA (MTA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfa501982fd5d2ad60fb4c1ede15d06
https://research.vumc.nl/en/publications/7399632f-e8f8-47aa-9aeb-f5d4933be7b0
https://research.vumc.nl/en/publications/7399632f-e8f8-47aa-9aeb-f5d4933be7b0