Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R. Matthew Strother"'
Autor:
Naftali Busakhala, Gabriel Kigen, Paul Waako, R. Matthew Strother, Fredrick Chite, Patrick Loehrer
Publikováno v:
Infectious Agents and Cancer, Vol 14, Iss 1, Pp 1-8 (2019)
Abstract Background AIDS-related Kaposi sarcoma (AIDS-KS), a common malignancy in Kenya is associated with high morbidity and mortality. AIDS-KS is treated using bleomycin and vincristine (BV) plus or minus doxorubicin in most low resource settings,
Externí odkaz:
https://doaj.org/article/e25fccc794aa4a3eb7879f746d777204
Autor:
Kirtika Patel, R. Matthew Strother, Francis Ndiangui, David Chumba, William Jacobson, Cecelia Dodson, Murray B. Resnic, Randall W. Strate, James W. Smith
Publikováno v:
African Journal of Laboratory Medicine, Vol 5, Iss 1, Pp e1-e7 (2016)
Background: Cancer is becoming a major cause of mortality in low- and middle-income countries. Unlike infectious disease, malignancy and other chronic conditions require significant supportive infrastructure for diagnostics, staging and treatment. In
Externí odkaz:
https://doaj.org/article/f465742ee86b4566acd902945540a387
Autor:
Soo Hee Jeong, Nuala A. Helsby, R. Matthew Strother, Michael Findlay, Kathryn E Burns, John A. Duley, Ottiniel Chavani, David Porter
Publikováno v:
Cancer Chemotherapy and Pharmacology. 87:711-716
Standard dosages of fluoropyrimidine chemotherapy result in severe toxicity in a substantial proportion of patients, however, routine pre-therapeutic toxicity prediction remains uncommon. A thymine (THY) challenge test can discriminate risk of severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a391c47782accc49405dfec269fe3c6
https://doi.org/10.1007/s00280-021-04240-2
https://doi.org/10.1007/s00280-021-04240-2
Autor:
Kumar Sandrasegaran, Todd C. Skaar, E. Gabriela Chiorean, Susan M. Perkins, David R. Jones, Anne Younger, Christopher Sweeney, Safi Shahda, Jennifer M. Funke, R. Matthew Strother, Noah M. Hahn, Daniela Matei, Bryan P. Schneider
Publikováno v:
Mol Cancer Ther
VEGF blockade does not uniformly result in clinical benefit. We evaluated safety, dose-limiting toxicities (DLT), recommended phase II dose (RP2D), antitumor efficacy, and exploratory biomarkers including pharmacogenomics and pharmacokinetics with so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b51ef2d78f5ab172d9cdce4dcbc7e9
https://europepmc.org/articles/PMC7541675/
https://europepmc.org/articles/PMC7541675/
Autor:
Kathryn E, Burns, Ottiniel, Chavani, Soo Hee, Jeong, John A, Duley, David, Porter, Michael, Findlay, R Matthew, Strother, Nuala A, Helsby
Publikováno v:
Cancer chemotherapy and pharmacology. 87(5)
Standard dosages of fluoropyrimidine chemotherapy result in severe toxicity in a substantial proportion of patients, however, routine pre-therapeutic toxicity prediction remains uncommon. A thymine (THY) challenge test can discriminate risk of severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8209ccf10709fa595982fa391ade7992
https://pubmed.ncbi.nlm.nih.gov/33687515
https://pubmed.ncbi.nlm.nih.gov/33687515
Autor:
Jon D Duke, Xu Han, Zhiping Wang, Abhinita Subhadarshini, Shreyas D Karnik, Xiaochun Li, Stephen D Hall, Yan Jin, J Thomas Callaghan, Marcus J Overhage, David A Flockhart, R Matthew Strother, Sara K Quinney, Lang Li
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 8, p e1002614 (2012)
Drug-drug interactions (DDIs) are a common cause of adverse drug events. In this paper, we combined a literature discovery approach with analysis of a large electronic medical record database method to predict and evaluate novel DDIs. We predicted an
Externí odkaz:
https://doaj.org/article/30d50f9a936c431ab6d2c59646a5fe17
Autor:
Christopher M. Florkowski, Peter M. George, Ottiniel Chavani, Berit Packert Jensen, R. Matthew Strother
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 142:125-135
The plasma 5,6-dihydrouracil/uracil (UH2/U) ratio is a possible phenotypic marker of dihydropyrimidine dehydrogenase (DPD) activity, hence an index of 5-fluorouracil (5-FU) response and toxicity. Studies have re-affirmed the value of 5-FU and 5,6-dih
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb6f8b1d9b27fdcb63dd940c74e68c6
https://doi.org/10.1016/j.jpba.2017.04.055
https://doi.org/10.1016/j.jpba.2017.04.055
Autor:
Fredrick Chite, Patrick J. Loehrer, Naftali Busakhala, Paul Waako, R. Matthew Strother, Gabriel Kigen
Publikováno v:
Infectious Agents and Cancer
Infectious Agents and Cancer, Vol 14, Iss 1, Pp 1-8 (2019)
Infectious Agents and Cancer, Vol 14, Iss 1, Pp 1-8 (2019)
Background AIDS-related Kaposi sarcoma (AIDS-KS), a common malignancy in Kenya is associated with high morbidity and mortality. AIDS-KS is treated using bleomycin and vincristine (BV) plus or minus doxorubicin in most low resource settings, with resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d4a65d095ebd8c68d1786aaac91aab
http://europepmc.org/articles/PMC6734447
http://europepmc.org/articles/PMC6734447
Publikováno v:
Seminars in Oncology. 45:318-319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8ec1bf52b973f723811aa78690752a
https://doi.org/10.1053/j.seminoncol.2018.08.003
https://doi.org/10.1053/j.seminoncol.2018.08.003
Autor:
Angie Secrest, Rafat Abonour, Michael J. Robertson, Kenneth Cornetta, R. Matthew Strother, Steven Messina-Graham, Jennifer E. Schwartz, David R. Jones, Lisa L. Wood, Shivani Srivastava, Hal E. Broxmeyer, Sherif S. Farag
Publikováno v:
Stem Cells and Development. 22:1007-1015
Delayed engraftment is a significant limitation of umbilical cord blood (UCB) transplantation due to low stem cell numbers. Inhibition of dipeptidyl peptidase (DPP)-4 enhanced engraftment in murine transplants. We evaluated the feasibility of systemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982ef8bb2fc865d4875ad5f8cdfbe9fb
https://doi.org/10.1089/scd.2012.0636
https://doi.org/10.1089/scd.2012.0636