Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R. Matthew Klein"'
Autor:
Ralf-Peter Czekay, Cynthia E. Wilkins-Port, Stephen P. Higgins, Jennifer Freytag, Jessica M. Overstreet, R. Matthew Klein, Craig E. Higgins, Rohan Samarakoon, Paul J. Higgins
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
Cellular migration, over simple surfaces or through complex stromal barriers, requires coordination between detachment/re-adhesion cycles, involving structural components of the extracellular matrix and their surface-binding elements (integrins), and
Externí odkaz:
https://doaj.org/article/dd56c16186b74e539fd175654b06a175
Autor:
Andrew E. Aplin, R. Matthew Klein
Supplementary Figures 1-6 from Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f91cf3c783f5d517db0ff535044f27
https://doi.org/10.1158/0008-5472.22380045.v1
https://doi.org/10.1158/0008-5472.22380045.v1
Autor:
Andrew E. Aplin, R. Matthew Klein
The depth of cell invasion into the dermis is a clinical determinant for poor prognosis in cutaneous melanoma. The signaling events that promote the switch from a noninvasive to invasive tumor phenotype remain obscure. Activating mutations in the ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b29264424995e89896264b743201748
https://doi.org/10.1158/0008-5472.c.6499431
https://doi.org/10.1158/0008-5472.c.6499431
Autor:
Andrew E. Aplin, R. Matthew Klein
Supplementary Figure Legends 1-6 from Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72506b148fe4ade5c20e2c77ed90a7b0
https://doi.org/10.1158/0008-5472.22380048.v1
https://doi.org/10.1158/0008-5472.22380048.v1
Autor:
R. Matthew Klein, Andrew E. Aplin
Publikováno v:
Cancer Research. 69:2224-2233
The depth of cell invasion into the dermis is a clinical determinant for poor prognosis in cutaneous melanoma. The signaling events that promote the switch from a noninvasive to invasive tumor phenotype remain obscure. Activating mutations in the ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f0bfdd2bd52c23e845dd332488a4a60
https://doi.org/10.1158/0008-5472.can-08-3201
https://doi.org/10.1158/0008-5472.can-08-3201
Publikováno v:
Cancer Research. 65:148-156
The formation of a microvascular endothelium plays a critical role in the growth and metastasis of established tumors. The ability of a fragment from the first type III repeat of fibronectin (III1C), anastellin, to suppress tumor growth and metastasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce21e75479e1134fed0ea4b9be28b60
https://doi.org/10.1158/0008-5472.148.65.1
https://doi.org/10.1158/0008-5472.148.65.1
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 28(2)
Anastellin is an angiogenesis inhibitor derived from the first type III repeat of fibronectin (FN). Anastellin binds to fibronectin and promotes the polymerization of soluble fibronectin into a highly polymerized form termed superfibronectin. In addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29866538ee001a3bef06b2e43a3fb2a
https://pubmed.ncbi.nlm.nih.gov/19379667
https://pubmed.ncbi.nlm.nih.gov/19379667
Publikováno v:
Molecular biology of the cell. 19(2)
The actin cytoskeleton controls multiple cellular functions, including cell morphology, movement, and growth. Accumulating evidence indicates that oncogenic activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c6a3b37d5d066edc064e4a1fd53dac
https://pubmed.ncbi.nlm.nih.gov/18045987
https://pubmed.ncbi.nlm.nih.gov/18045987
Autor:
Paul J. Higgins, R. Matthew Klein
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 10, Iss 1, p 114 (2011)
Molecular Cancer, Vol 10, Iss 1, p 114 (2011)
Background The initial use of BRAF targeted therapeutics in clinical trials has demonstrated encouraging responses in melanoma patients, although a rise in drug-resistant cells capable of advancing malignant disease has been described. The current st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f4de213511248f3bca37e9c8082fb6
http://europepmc.org/articles/PMC3180434
http://europepmc.org/articles/PMC3180434
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