Zobrazeno 1 - 10
of 96
pro vyhledávání: '"R. Mark L Buller"'
Publikováno v:
BioTechniques, Vol 32, Iss 1, Pp 160-171 (2002)
Cytokines are pivotal to a balanced innate or cell-mediated immune response, can be indicative of disease progression and/or resolution, and are being evaluated as therapeutics. There is a need to purify and/or to measure key cytokines rapidly with a
Externí odkaz:
https://doaj.org/article/438ebfef0fcf47a69af1fb06fa34b29f
Autor:
Allan Jensen, R. Mark L. Buller, Mark N. Prichard, June Ann D'Angelo, Sarah L. George, Henriette Schjønning Nielsen, Johan Lantto, Scott Parker, Donald F. Smee
Publikováno v:
Antiviral research. 195
Orthopoxviruses such as variola and monkeypox viruses continue to threaten the human population. Monkeypox virus is endemic in central and western Africa and outbreaks have reached as far as the U.S. Although variola virus, the etiologic agent of sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44d7ffad40773b9a47db4f0c26c8f9a
https://pubmed.ncbi.nlm.nih.gov/34530009
https://pubmed.ncbi.nlm.nih.gov/34530009
Autor:
Wieke Freudenburg, Madhav Gautam, Pradipta Chakraborty, Jared James, Jennifer Richards, Alison S Salvatori, Aaron Baldwin, Jill Schriewer, R Mark L Buller, John A Corbett, Dorota Skowyra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e52408 (2013)
Autoimmune destruction of insulin producing pancreatic β-cells is the hallmark of type I diabetes. One of the key molecules implicated in the disease onset is the immunoproteasome, a protease with multiple proteolytic sites that collaborates with th
Externí odkaz:
https://doaj.org/article/ce511bb44e184cc4a11634b4d99f5488
Publikováno v:
Advances in Virology, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/a4021c2ae274408183a3e5977d0520dd
Publikováno v:
PLoS Pathogens, Vol 4, Iss 12, p e1000249 (2008)
Poxviruses subvert the host immune response by producing immunomodulatory proteins, including a complement regulatory protein. Ectromelia virus provides a mouse model for smallpox where the virus and the host's immune response have co-evolved. Using
Externí odkaz:
https://doaj.org/article/2503160090c6487e97ac92a673524df2
Autor:
Daniel Van Aartsen, Christopher S. Eickhoff, Anne S. De Groot, Isaac G. Sakala, Krystal A. Meza, Leonard Moise, William D. Martin, Linda Peng, Daniel F. Hoft, R. Mark L. Buller, Jill Schriewer, Frances Terry
Publikováno v:
Vaccine
Influenza world-wide causes significant morbidity and mortality annually, and more severe pandemics when novel strains evolve to which humans are immunologically naïve. Because of the high viral mutation rate, new vaccines must be generated based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b26f3a7285dde6f725dc8d5f8402583
https://pubmed.ncbi.nlm.nih.gov/31331771
https://pubmed.ncbi.nlm.nih.gov/31331771
Autor:
Benjamin S. Christmann, Jason M. Moran, Joshua D. Stafford, John A. Corbett, Zachary R. Shaheen, R. Mark L. Buller
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Double-stranded (ds) RNA, both synthetic and produced during virus replication, rapidly stimulates MAPK and NF-κB signaling that results in expression of the inflammatory genes inducible nitric oxide synthase, cyclooxygenase 2, and IL-1β by macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8744f783f10fd768ef204b9472ff85cd
https://pubmed.ncbi.nlm.nih.gov/30811246
https://pubmed.ncbi.nlm.nih.gov/30811246
Autor:
Larry Sallans, Victoria A. Olson, Tessa Moir-Savitz, Nadia F. Gallardo-Romero, R. Mark L. Buller, Erin Touchette, Inger K. Damon, Gopi Patel, Johanna S. Salzer, Catherine M.T. Sherwin, Scott Parker, Pankaj B. Desai, Hari Krishna Ananthula, Daniel Kalman, Milton H. Werner
Publikováno v:
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Pharmacology & Toxicology
BMC Pharmacology & Toxicology
Background Several tyrosine kinase inhibitors (TKIs) developed as anti-cancer drugs, also have anti-viral activity due to their ability to disrupt productive replication and dissemination in infected cells. Consequently, such drugs are attractive can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3eb62b1f5ab3cf94074758fa3aad464
https://doi.org/10.1186/s40360-018-0270-x
https://doi.org/10.1186/s40360-018-0270-x
Autor:
Bethany D. Harris, R. Mark L. Buller, Jeffrey A. Speir, Jill Schriewer, Shane Miersch, Sachdev S. Sidhu, Mark R. Walter, Ashlesha Deshpande, Srilalitha Kuruganti
Publikováno v:
Journal of Biological Chemistry. 291:447-461
Exogenous cytokine therapy can induce systemic toxicity, which might be prevented by activating endogenously produced cytokines in local cell niches. Here we developed antibody-based activators of cytokine signaling (AcCS), which recognize cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eafec645956533e80e0f40782576ad9
https://doi.org/10.1074/jbc.m115.665943
https://doi.org/10.1074/jbc.m115.665943
Autor:
Wayne M. Yokoyama, Marco Colonna, Ryan W. Crump, Jill Schriewer, Ed Hembrador, Aaron S. Rapaport, Hanspeter Pircher, Jian Gao, Gaelle Le Friec, Béatrice Plougastel, R. Mark L. Buller, Yaming Wang, Susan Gilfillan, Marina Cella
Publikováno v:
Immunity. 43(6):1112-1124
CD8(+) T cells and NK cells protect from viral infections by killing virally infected cells and secreting interferon-γ. Several inhibitory receptors limit the magnitude and duration of these anti-viral responses. NKG2A, which is encoded by Klrc1, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e665e1ceb739af2ccf45c5aecddc2f