Zobrazeno 1 - 10
of 214
pro vyhledávání: '"R. Manservigi"'
Autor:
Lara Stevanato, Abdel Naser Zaid, Romeo Romagnoli, Pier Giovanni Baraldi, Stefano Manfredini, R. Manservigi
Publikováno v:
Scopus-Elsevier
a new series of 6-substituted N1- and N2 -β-D-ribofuranosyl-pyrazolo[3,4-d]pyridazin-7(6H)-one derivatives (8a-g, 9b-d and 9f-g) has been prepared in the aim to explore the structure-activity relationships and improve the antiviral activity of a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10113df28ee30b5c025042d2a512b09
https://doi.org/10.1080/07328319808004307
https://doi.org/10.1080/07328319808004307
Autor:
Giovanni Ciarrocchi, Federico Focher, R. Manservigi, Antonio Carcuro, Silvio Spadari, Anna Garbesi, Stefano Iotti, Giovanni Maga, Federico Arcamone, Massimo L. Capobianco, Francesco Paolo Colonna
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652742876ddd24b2c5b1283c7eb2a78c
https://doi.org/10.1002/chin.199321252
https://doi.org/10.1002/chin.199321252
Autor:
Romeo Romagnoli, Stefano Manfredini, Lara Stevanato, Abdel Naser Zaid, R. Manservigi, Pier Giovanni Baraldi
Publikováno v:
ChemInform. 30
a new series of 6-substituted N1- and N2 -β-D-ribofuranosyl-pyrazolo[3,4-d]pyridazin-7(6H)-one derivatives (8a-g, 9b-d and 9f-g) has been prepared in the aim to explore the structure-activity relationships and improve the antiviral activity of a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7084f5c8b9993267cacf564022145c0f
https://doi.org/10.1002/chin.199916219
https://doi.org/10.1002/chin.199916219
Autor:
S, Spadari, G, Maga, F, Focher, G, Ciarrocchi, R, Manservigi, F, Arcamone, M, Capobianco, A, Carcuro, F, Colonna, S, Iotti
Publikováno v:
Journal of Medicinal Chemistry. 35:4214-4220
We have demonstrated that herpes simplex 1 (HSV1) thymidine kinase (TK) shows no stereospecificity for D- and L-beta-nucleosides. In vitro, L enantiomers are not recognized by human TK, but function as specific substrates for the viral enzyme in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d37ec540b06cf05270c73a56ec20bbd
https://doi.org/10.1021/jm00100a029
https://doi.org/10.1021/jm00100a029
Publikováno v:
Intervirology. 44(4)
The heterocomplex of glycoproteins H (gH) and L (gL) of herpes simplex virus type 1 (HSV-1) is essential for viral infectivity and is involved in viral penetration, cell-to-cell spread, and syncytium formation. We constructed an HSV-1 mutant expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672f26b2c5ca543963333c71df2e246e
https://pubmed.ncbi.nlm.nih.gov/11509886
https://pubmed.ncbi.nlm.nih.gov/11509886
Publikováno v:
Brain research. 835(1)
One goal of neuroscience is to define the molecular and cellular basis for behavior and neurological diseases. A novel approach to this problem is based on the use of viral vectors to transfect specific genes into specific brain cell populations. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cbd9cb46f7ce47ce881176e0c3e5952
https://pubmed.ncbi.nlm.nih.gov/10448194
https://pubmed.ncbi.nlm.nih.gov/10448194
Publikováno v:
The new microbiologica. 18(4)
Herpes simplex virus 1 (HSV-1) mutants selected in Vero cells either for resistance to plaque development inhibition (PDI) (P1, P2 and P3) or for resistance to neutralization (N1, N2, and N3) against an anti-glycoprotein D (gD) monoclonal antibody (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47bc7659913e4bbc3ceb9e8a7984542a
https://pubmed.ncbi.nlm.nih.gov/8590387
https://pubmed.ncbi.nlm.nih.gov/8590387
Publikováno v:
Intervirology. 38(6)
The type 1 and type 2 glycoprotein G (gG1 and gG2) of herpes simplex virus (HSV) were expressed in Escherichia coli as fusion proteins with the maltose binding protein (MBP) using the pMAL-c2 expression vector. The MBP-gG1 fusion protein contains all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83d208a9e1435b16ad9e679815c26d60
https://pubmed.ncbi.nlm.nih.gov/8880385
https://pubmed.ncbi.nlm.nih.gov/8880385
We have purified Herpes simplex type 1 (HSV1) uracil-DNA glycosylase from the nuclei of HSV1-infected HeLa cells harvested 8 h post-infection, at which time the induction of the enzyme is a maximum. The enzyme has been shown to be distinct from the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a41e7d655ec31e2f7a5e1072d52727
https://europepmc.org/articles/PMC1134197/
https://europepmc.org/articles/PMC1134197/
Autor:
M P, Grossi, A, Caputo, S, Zucchini, R, Bozzini, P C, Marconi, R, Manservigi, G, Barbanti-Brodano, P G, Balboni
Publikováno v:
The Year in immunology. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec05e2576f2640466f97edac6acda5b5
https://pubmed.ncbi.nlm.nih.gov/8396820
https://pubmed.ncbi.nlm.nih.gov/8396820