Zobrazeno 1 - 10
of 195
pro vyhledávání: '"R. M. Zinkernagel"'
Autor:
Karl S. Lang, Aleksandra A. Pandyra, Hans Hengartner, Namir Shaabani, Haifeng C. Xu, Nadine Honke, Isaac S. Harris, Vitaly I. Pozdeev, Dieter Häussinger, S Kumar Maney, Melanie Grusdat, R M Zinkernagel, David R. McIlwain, Elisabeth Lang, Bernhard Odermatt, Pamela S. Ohashi, Mike Recher, Philipp A. Lang, Tak W. Mak, Dirk Brenner
Publikováno v:
Cell Death and Differentiation
Cluster of differentiation (CD)8(+) T cells are like a double edged sword during chronic viral infections because they not only promote virus elimination but also induce virus-mediated immunopathology. Elevated levels of reactive oxygen species (ROS)
The CD4 and CD8 molecules are involved in T cell differentiation and activation. Nevertheless, efficient thymic maturation of helper T cells has been shown in the absence of the CD4 molecule. These CD4-deficient helper T cells expressed alpha beta-TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1935b561c28117ce40ca97418c4e4c
https://ora.ox.ac.uk/objects/uuid:c61230a0-6472-4f78-b787-9e43c630f6fe
https://ora.ox.ac.uk/objects/uuid:c61230a0-6472-4f78-b787-9e43c630f6fe
The size of the Ab repertoire has been estimated to comprise theoretically somewhere between > 10(10) and approximately 10(4) specificities, dependent on the criteria used. In an attempt to estimate the anti-viral protective Ab repertoire of the mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29efd57bf990576b97715641ad797854
https://ora.ox.ac.uk/objects/uuid:7d61ff2f-c9a4-4c5f-9ea6-c9f1065a498e
https://ora.ox.ac.uk/objects/uuid:7d61ff2f-c9a4-4c5f-9ea6-c9f1065a498e
Induction of immunity to a viral protein that had been transfected into a tumor cell line was studied. The nucleoprotein (NP) of vesicular stomatitis virus (VSV) was used as a model tumor-associated Ag after transfection into EL-4, and H-2b thymoma o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a30f5620cb7fc211ef94ae4f2bd4098
https://ora.ox.ac.uk/objects/uuid:16f612f1-7753-470d-8739-1b12c090cacb
https://ora.ox.ac.uk/objects/uuid:16f612f1-7753-470d-8739-1b12c090cacb
Autor:
K A Campbell, Tadamitsu Kishimoto, H Kikutani, Hans Hengartner, R M Zinkernagel, Annette Oxenius, C R Maliszewski, Martin F. Bachmann
Publikováno v:
The Journal of Experimental Medicine
CD40-CD40 ligand (CD40L) interaction is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. The role of the CD40-CD40L interaction in the induction of antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71985f1b1feba7916de25407dab889a
https://doi.org/10.1084/jem.183.5.2209
https://doi.org/10.1084/jem.183.5.2209
MHC class II presentation of antigenic peptides derived from soluble proteins is usually preceded by antigenic uptake via (nonreceptor-mediated) endocytosis by professional APCs, followed by processing in endosomal compartments. Although in vitro alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cb091091757f9e20ddb44504d05744
https://ora.ox.ac.uk/objects/uuid:5392f221-8cca-48df-a0fe-333f48cded54
https://ora.ox.ac.uk/objects/uuid:5392f221-8cca-48df-a0fe-333f48cded54
Autor:
R. M. Welsh, H. Momtaz, A. R. Thomsen, Y. Watanabe, V. Combes, X. Kong, W. T. Rothwell, M. Kanno, B. Kazemi, A. Shirani, D. Khachapuridze, M. Odenthal, R. Yanagisawa, Z. Ling, P. S. Ohashi, M. L. Freeman, Y. Lee, M Hernández, J. Miles, G. N. Milligan, Z. Liang, Paul G. Thomas, J. Tanaka, Ralph A. Tripp, E. Aguirre, S. Workman, A. Aguilar-Setien, T. Laurinolli, S. Lin, D. Kłosowska, S. Wang, O. Ikeda, K. Ostrow, K. Bogunia-Kubik, U. Kalinke, K. Lee, T. M. Ha, Katherine Kedzierska, G. K. Vikulov, M. Khodabandeh, R. J. Betts, Lisbeth Berrueta, M. Pasparakis, E. Kekäläinen, M. Hoshi, Z. Zeng, T. Toma, G. E. Kaiko, K. Huang, K. S. Lang, T. Ito, R. Hancock, L. Pham Van, U. B. Hellstrom, A. Lange, A. Meyers, R. Petraityte, E. Rizopulu, F. Xu, R. M. Zinkernagel, Y. Girerd-Chambaz, Katayoun Samimi-Rad, Seyed Moayed Alavian, T. Hsu, M. Schaller, D. S. Bowden, M. S. Rolph, H. Fujii, P. A. Lang, M. Akihiro, T. Furuta, S. P. Sylvan, Florian Kern, H. Shibata, Y. Ogawa, X. Zhang, F. Lai, H. Kida, U. Kumaraguru, J. Cardosa, Peter C. Doherty, Mark M. Davis, J. Pätzold, M. Matloubian, Y. Sakoda, P. Chaux, S. Lai, N. Nakajima, Y. Chen, K. Markiewicz, T. Tran, P. Chong, I. Lagereva, B. Sierra, E. Nazarov, M. Kikuchi, H. Ishida, C. Ferrari, David L. Woodland, A. G. Bean, M. H. Nelson, Z. J. Chen, D. M. Estes, M. R. Azar Pajoh, K. Vogt, M. A. Blackman, R. Todaka, S. Ma, W. Li, J. Sun, P. Lukianov, K. Gärtner, A. Vaheri, P. Wark, A. W. S. Yeung, A. Matsumura, L. Cao, I. Beĭkin, M. Recher, K. Eriksson, V. Wang, D. Webster, H. Yoshizawa, K. Hosiawa-Meagher, P. Sun, K. Katayama, H. Bisceglia, J. Du, M. Matsumoto, Z. Qu, P. J. Gaddi, M. R. Edwards, J. R. Carlyle, T. U. Aripova, A. G. Telcian, J. S. Yi, V. I. Afanasyeva, R. Kumar, B. Shaffaedin, S. Schoenberger, A. S. Khodjaeva, S. C. Weaver, D. Verthelyi, R. Sugamata, F. Ershov, R. Jafari Shakib, G. N. Feketea, A. Brook, H. Lei, Z. Qin, F. Vahedi, M. G. Guzmán, J. Huang, C. Ventura, A. Izquierdo, W. Siew Cheng, T. Kawamura, H. Keyvani, C. Ørskov, C. Tami, T. T. Tran, J. H. Fine, H. Kato, Z. J. Rakhmankulova, Y. A. Chen, J. C. Huang, K. Kobayashi, K. Kitamura, W. F. Carson, Azam Bolhassani, R. Rochford, J. Li, M. A. Bolkov, H. Liu, T. Ospelnikova, P. Storm, S. T. Smiley, L. A. Stanciu, F. Sánchez-García, M. Nakayama, M. B. Moreno-Altamrano, T. Wada, J. Deng, A. Perez, M. Puig, N. W. Lukacs, G. Liang, S. Jeon, L. C. Bonifaz-Alfonzo, S. Shimada, G. García, H. Marshall, A. Górski, S. Phipps, H. Tran, H. Kanegane, G. Korczak-Kowalska, C. Boni, J. Kyd, L. Rocha-Zavaleta, F. Garib, H. T. Q. Vu, M. Simadu, J. P. Twohig, B. G. Oliver, Shine Thomas, D. Chu, S. M. Cuff, Y. Lin, Z. Tian, S. Mäkelä, N. Mosaffa, M. Gołebiowska Wawrzyniak, R. Anderson, M. Brückel, T. P. Salazar-Mather, G. E. Grau, H. G. Durkin, I. R. Humphreys, W. Xi, H. Lin, Y. Sakakibara, A. Toga, P. Chen, K. Saito, Yasaman Taslimi, Leidith Berrueta-Carrillo, Y. Itoh, J. Sung, F. Liao, V. Emery, Y. Sato, S. Voigt, H. Horie, L. Simson, M. Larki, A. Hayashi, S. L. Rossi, R. Milne, R. Mirzaei, B. Evengård, Y. Liu, P. G. Mohr, B. Weiss-Steider, T. Nishimura, M. J. Crane, M. Høgh-Petersen, E. Sandalova, A. Dehghan, Z. Sharifnia, E. C. Y. Wang, H. Volk, M. L. Mora-García, C. M. Hogaboam, J. M. Clingan, A. T. Tan, N. Evstigneeva, P. Knolle, S. Hsieh, I. Kucinskaite-Kodze, M. Alvarez, Darrell L. Peterson, D. Tran, Sima Rafati, T. Seya, S. Marques, Tania Cukalac, F. Goshima, L. Perea-Martìnez, N. La Gruta, S. Kawachi, I. Hirono, M. Raeiszadeh, M. Koura, P. Holst, P. Kourilsky, R. Ganjali, J. P. Christensen, N. Hirankarn, L. Yao, A. Jakimiuk, J. Browne, I. V. Nesterova, M. Lu, M. Rezvani, C. Lin, B. A. Wu-Hsieh, G. P. Nolan, L. P. Bykova, B. Agrawal, K. Pérz-Saldaña, P. M. Niedzwiedzka-Rystwej, B. Pliego-Rivero, M. Farhadi, A. P. Godovalov, E. W. Newell, G. Hsu, L. T. P. Nguyen, Y. Chang, F. Rashidi, J. Tanguy, P. Kaiser, H. Lauterbach, F. Saito, R. Chua, P. W. Mason, I. A. Pashnina, H. Neekdan, Jamie Rossjohn, M. Toporkova, Luisa Barboza, H. Mitsui, M. C. Zaragoza-Ortega, E. L. Istomina, L. T. Dang, S. N. Boyarsky, A. Mesci, S. Vázquez, O. A. Aguilar, K. Shinoda, C. G. Silva, Stacie Woolard, M. Sadeghi, M. Jones, Farnaz Zahedifard, L. Wyatt, H. Dobashi, J. Simas, Henry Montes, N. Levchik, P. Kokhaei, C. Bartholdy, S. L. Kunkel, K. Suzuki, E. E. Ooi, Ashish Kumar, I. P. Balmasova, J. Ettinger, T. Nakayama, A. J. Zajac, R. Eftekhari, R. Lachmann, H. Inoue, D. Häussinger, D. Zhao, S. Koyasu, Chi Ma, Y. Keynan, M. V. Chikhladze, A. Hsu, F. Khodapanahandeh, W. Sun, K. Ogasawara, L. S. Tsai, M. Asano, A. Yachie, Stephanie Gras, J. Körner, N. Gaius, R. Gholamian-Dehkordi, Y. R. Sepiashvili, Y. Lu, Xinghao Ding, N. Vasilakis, D. Laccabue, H. Wu, J. Feng, S. Liu, X. Liang, M. Nowakowski, M. Krönke, K. I. Mattaei, D. V. Tran, K. L. O. Antonsdotter, K. Wong, B. Tzang, B. Dabirmanesh, H. Hochrein, Stephen J. Turner, A. Kulawik, D. Omagari, L. Skljar, O. Kovalenko, M. Seishima, H. Dienes, E. Rubinstein, L. Cervantes-Barragan, Y. Kim, I. Moro, U. Protzer, R. Sun, T. Mironova, D. M. Kemeny, J. Tavakkol Afshari, J. Mustonen, J. W. Lowenthal, T. P. Arstila, S. Kiabi, J. L. Munoz-Jordan, Z. S. Kamalov, Z. Wawrzyniak, C. Ahlm, K. Soda, Z. Mohtasham Amiri, Y. Aratani, T. Chumachenko, Y. Teruhito, Ali Eslamifar, J. Pedras-Vasconcelos, A. P. Durbin, N. J. C. King, H. Vu, M. Suter, T. Burgess, Z. Atai, T. Vo, E. R. Jellison, F. Li, M. C. Mohanty, E. V. Vlasova, T. Ball, H. Ishigaki, I. A. Tuzankina, C. R. Stewart, A. Flavigny, L. Nguyen, T. Sata, S. Akira, V. Kalihevich, E. Jaskula, O. Takeuchi, C. Aitken, K. Mohtashami, M. Bharadwaj, A. Bertoletti, Melisa Colmenares, H. Jenssen, S. Chen, J. Ramos-Castaneda, J. S. Ahn, D. Xilei, L. Hsu, A. Verschoor, M. Bandehpour, H. D. Volk, M. H. Bluth, M. Du, M. Tadashi, S. Mahalingam, C. Tsai, M. Arikata, Sophie A. Valkenburg, A. Monroy-García, M. Okamatsu, K. Rytwinski, K. Schmolke, D. B. Lewis, Siham Salmen, H. A. Mahgoub, C. Butts, A. Krishnamurthy, S. Moneer, H. Kondo, Ali Khamesipour, P. Ghyasemi-Dehkordi, L. Valdés, R. Aoki, L. A. Sandoval-Escobar, H. Ito, Natasha G. Swan, K. Dahlman-Wright, B. J. Hanson, P. M. Hansbro, P. Foster, M. Yasunami, Q. Ge, K. Tomizawa, U. Nivarthi, W. Wu, J. McCluskey, Y. Wang, J. Lee, J. McGrath, K. Yamamoto, J. Jan, L. Kjer-Nielsen, S. L. Johnston, H. Takaki, N. Prabhu, T. J. Standiford, B. Moss, L. Sanchez, P. Sodsai, M. Guzman, P. S. Foster, E. V. Shmeleva, A. Shestakov, T. Satoh, R. S. Kuzyaev, P. Wierzbicki, K. Fink, H. Rafat Panah, H. Ohtaki, J. Nakkuntod, E. S. Malova, K. Hirayama, H. Yagita, A. Zvirbliene, S. V. Mayer, B. Jin, L. Zuo, Z. Ardemasova, N. Harris, A. Kozar, S. Vostrukhin, J. Chang, C. Zhao, S. Kurata, S. Noorbakhsh, M. Muramatsu, E. Guillemard, O. Mikhailova, T. V. Vo, C. Fuentes-Miranda, P. Chaplin, D. Stabenow, N. Burdin, S. C. D. D. Abedelmalek, Y. Kuznetsova, Mohammad Taghikhani, D. K. Hong, A. B. Pérez, S. Yuichi, J. Hernández-Montes, O. Cruz y Cruz, T. Maciejewski, G. Siritsa, Elham Mohit, K. Morita, Y. Jiang, D. K. Krishnadas, K. Sasnauskas, W. M. Deptuła, H. Nguyen, J. Borysowski, K. Komiyama, C. Chuang, E. Markelova, N. Babel, K. R. Fowke, D. Thammanichanond, R. Kassub, C. Chirathaworn, A. Rizopulu, I. Gorelova, N. Van Rooijen, F. Pak, N. Bourne, D. Townsend, C. Krings, Y. Nishiyama, B. Ludewig, E. R. Winkelmann, J. M. Deshpande, S. Tsai, P. A. MacAry, Y. Mitsuya, S. Marashi, J. Niu, N. Watanabe, J. Schrezenmeir, R. M. Locksley, J. Jang, N. D. Yushchuk, Y. Su, S. Chowdhury, J. A. Juno, F. Ghazi, M. Hellard, H. Hengartner, Y. Ohmoto, W. Yang, R. B. Tesh, A. W. Ho, P. Kupatawintu, Z. Wang, P. Brundin, S. de la Motte, S. C. Bendall, M. Oshima, P. Tangkijvanich, T. Nagao, B. M. M. Moreno-Altamirano
Publikováno v:
International Immunology. 22:ii27-ii48
Autor:
Hans Hengartner, R M Zinkernagel
Publikováno v:
Scandinavian Journal of Immunology. 62:195-201
Autor:
R M, Zinkernagel, H, Hengartner
Publikováno v:
Scandinavian Journal of Immunology. 60:9-13
Resistance of vertebrate hosts against infections comprises important natural or innate resistance combined with adaptive immune responses of T and B cells. Viruses, bacteria or classical parasites all probe the limit of immune responses and of immun
Publikováno v:
Journal of Virology. 71:1802-1807
The role of B7 binding CD28 in the regulation of T- and B-cell responses against viral antigens was assessed in transgenic mice expressing soluble CTLA4-Hgamma1 (CTLA4-Ig tg mice) that blocks B7-CD28 interactions. The results indicate that transgenic