Sequence Alignment between vWF and Peptides Inhibiting the vWF-collagen Interaction Does not Result in the Identification of a Collagen-binding Site in vWF

Autor: J. J. Sixma, G Vandecasteele, Eric G. Huizinga, R. M. Van Der Plas, Karen Vanhoorelbeke, Hans Deckmyn, S Vauterin

Publikováno v: Thrombosis and Haemostasis. 84:621-625

SummaryWe previously found that two peptides (N- and Q-peptide) selected by phage display for binding to an anti-vWF antibody, were able to inhibit vWF-binding to collagen (1). The sequence of those peptides could be aligned with the sequence in vWF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c1f60f53442ab0387d38a015e27f527
https://doi.org/10.1055/s-0037-1614077

Binding of von Willebrand factor to collagen type III: role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains

Autor: R M, van der Plas, L, Gomes, J A, Marquart, T, Vink, J C, Meijers, P G, de Groot, J J, Sixma, E G, Huizinga

Publikováno v: Thrombosis and haemostasis. 84(6)

Binding of von Willebrand Factor (vWF) to sites of vascular injury is the first step of hemostasis. Collagen types I and III are important binding sites for vWF. We have previously determined the three-dimensional structure of the collagen binding A3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8573631113b63f1835444beee07a64cc
https://pubmed.ncbi.nlm.nih.gov/11154106

Platelet adhesion to collagen: an update

Autor: J J, Sixma, G H, van Zanten, E G, Huizinga, R M, van der Plas, M, Verkley, Y P, Wu, P, Gros, P G, de Groot

Publikováno v: Thrombosis and haemostasis. 78(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0cba53ffb04eabec275b3e43b6d695cc
https://pubmed.ncbi.nlm.nih.gov/9198192

A predictive substrate model for rat glutathione S-transferase 4-4

Autor: R. M. Van Der Plas, G. M. Donne-Op Den Kelder, P. J. Nieuwenhuizen, M.J. de Groot, Jan N. M. Commandeur, Nico P. E. Vermeulen, E. M. Van Der Aar

Publikováno v: de Groot, M J, van der Aar, E M, Nieuwenhuizen, P J, van der Plas, R M, Donné-Op den Kelder, G M, Commandeur, J N M & Vermeulen, N P E 1995, ' A predictive substrate model for rat glutathione S-transferase 4-4. ', Chemical Research in Toxicology, vol. 8, pp. 649-658 . https://doi.org/10.1021/tx00047a004
Chemical Research in Toxicology, 8, 649-658. American Chemical Society

Molecular modeling techniques have been used to derive a substrate model for class mu rat glutathione S-transferase 4-4 (GST 4-4). Information on regio- and stereoselective product formation of 20 substrates covering three chemically and structurally

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac1ac57452bb4f63777d61ef35ef801
https://research.vu.nl/en/publications/97701245-5bdf-4e2e-964a-5ae65ae9ed09