2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play

Autor: R, Infantino, S, Boccella, D, Scuteri, M, Perrone, F, Ricciardi, R M, Vitale, R, Bonsale, A, Parente, I, Allocca, A, Virtuoso, C, De Luca, C, Belardo, P, Amodeo, V, Gentile, G, Cirillo, G, Bagetta, L, Luongo, S, Maione, F, Guida

Publikováno v: Biomedicine & Pharmacotherapy. 156:113844

The 2-pentadecyl-2-oxazoline (PEA-OXA) is a natural compound with protective action in neuro-inflammation. We have previously shown that PEA-OXA behaves as an α2 adrenergic receptor (α2AR) antagonist and a putative protean agonist on histamine H3 r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b11cc7cad5897f23ce9abab4779d05a
https://doi.org/10.1016/j.biopha.2022.113844

Ac10c: A medium-ring, cycloaliphatic Cα,α-disubstituted glycine. Incorporation into model peptides and preferred conformation

Autor: A. Moretto, F. Formaggio, M. Crisma, C. Toniolo, M. Saviano, R. M. Vitale, E. Benedetti, IACOVINO, Rosa

Two complete series of N-protected oligopeptide esters to the pentamer level from 1-amino-cyclodecane-1-carboxylic acid (AC10C), an α-amino acid conformationally constrained through a medium-ring Ciα↔Ciα cyclization, and either the L-Ala or Aib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3977::c734cbb02ad4b03c65b20394be015ba4
http://hdl.handle.net/11591/185475

STRUCTURAL ANALYSIS OF THE TRANSCRIPTIONAL REGULATOR BALD16 FROM SULFOLOBUS SOLFATARICUS

Autor: A. Di Fiore, R. M. Vitale, G. Fiorentino, R. Ronca, C. Pedone, S. Bartolucci, G. De Simone

Publikováno v: XXXVI Congresso dell'AIC, Copanello di Stalettì, 2007
info:cnr-pdr/source/autori:A. Di Fiore, R. M. Vitale, G. Fiorentino, R. Ronca, C. Pedone, S. Bartolucci and G. De Simone/congresso_nome:XXXVI Congresso dell'AIC/congresso_luogo:Copanello di Stalettì/congresso_data:2007/anno:2007/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::78a056cd46f86462fea9a2587d0818e2
https://publications.cnr.it/doc/77120

Ac10c: a medium-ring, cycloaliphatic Calpha,alpha-disubstituted glycine. Incorporation into model peptides and preferred conformation

Autor: A, Moretto, F, Formaggio, M, Crisma, C, Toniolo, M, Saviano, R, Iacovino, R M, Vitale, E, Benedetti

Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 57(4)

Two complete series of N-protected oligopeptide esters to the pentamer level from 1-amino-cyclodecane-1-carboxylic acid (Ac10c), an alpha-amino acid conformationally constrained through a medium-ring Calphai--Calphai cyclization, and either the L-Ala

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae4c16e015eacddeffde45c1f543f9a2
https://pubmed.ncbi.nlm.nih.gov/11328488

Structural characterization of the functional regions in the archaeal protein Sso7d

Autor: Giovanni Renzone, Annamaria Guagliardi, Mosè Rossi, Andrea Scaloni, Pietro Amodeo, Rosa Maria Vitale

Publikováno v: Proteins
67 (2007): 189–197. doi:10.1002/prot.21220
info:cnr-pdr/source/autori:Renzone G; Vitale RM; Scaloni A; Rossi M; Amodeo P; Guagliardi A./titolo:Structural characterization of the functional regions in the archaeal protein Sso7d./doi:10.1002%2Fprot.21220/rivista:Proteins (Print)/anno:2007/pagina_da:189/pagina_a:197/intervallo_pagine:189–197/volume:67

Sso7d from the extreme thermophilic crenarchaeon Sulfolobus solfataricus is a multifunctional protein in in vitro assays, whose in vivo role is still puzzling. Crystals of Sso7d in complex with DNA elucidated the protein surface involved in the bindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca70a5a555276461823b82cda0e2bcf
https://publications.cnr.it/doc/169310