Výsledky vyhledávání - "R. M. Trikin"

DNA with a 2-Pyridyldithio Group at the C2' Atom: A Promising Tool for the Crosslinking of the MutS Protein Preserving Its Functional Activity

Autor: Peter Friedhoff, Elena A. Kubareva, T. S. Oretskaya, R. M. Trikin, Elena A. Romanova, Valeri Metelev, M. V. Monakhova, E. M. Kosaretskiy, S. A. Perry

Publikováno v: Russian Journal of Bioorganic Chemistry. 47:447-460

Noncovalent interactions between DNA and proteins are vital for cells. DNA-protein crosslinking may occur due to various endogenous and exogenous factors, as well as chemotherapeutic agents, and often affects the performance of DNA-binding proteins.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44f28fdf03f25490b542dafd361c1ed0
https://doi.org/10.1134/s1068162021020205

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Functional Specifics of the MutL Protein of the DNA Mismatch Repair System in Different Organisms

Autor: Tatiana S. Oretskaya, Elena A. Kubareva, M. A. Milakina, R. M. Trikin, M. V. Monakhova

Publikováno v: Russian Journal of Bioorganic Chemistry. 46:875-890

A DNA mismatch repair (MMR) system is found in all living organisms. MMR dysfunction at any step of DNA repair leads to an accumulation of mutations in the cell, thus decreasing the viability. In most organisms, the MutL protein plays a key role in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b31c6301123c224c85020948a9c7fa76
https://doi.org/10.1134/s1068162020060217

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