Zobrazeno 1 - 10
of 68
pro vyhledávání: '"R. M. Santella"'
Publikováno v:
Science. 272:1083h-1087
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(11)
Chronic hepatitis B virus (HBV) infection and aflatoxin B(1) (AFB(1)) exposure interact synergetically to induce hepatocellular carcinoma. One suggested mechanism for this interaction is the enhanced activation of AFB(1) in chronically HBV-infected i
Autor:
A, Hoque, D, Albanes, S M, Lippman, M R, Spitz, P R, Taylor, E A, Klein, I M, Thompson, P, Goodman, J L, Stanford, J J, Crowley, C A, Coltman, R M, Santella
Publikováno v:
Cancer causescontrol : CCC. 12(7)
To conduct timely epidemiologic investigations of molecular/genetic markers that may contribute to the development of prostate, lung, colorectal, or other cancers within the Selenium and Vitamin E Cancer Prevention Trial (SELECT), and to evaluate int
Autor:
G, Motykiewicz, E, Małusecka, J, Michalska, E, Kalinowska, J, Włoch, D, Butkiewicz, A, Mazurek, D, Lange, F P, Perera, R M, Santella
Publikováno v:
Cancer detection and prevention. 25(4)
Although the etiology of the majority of human breast cancers is unknown, environmental carcinogens are suspected to play a role. In this study, we investigated polycyclic aromatic hydrocarbon-DNA adducts in 78 breast cancer patients and benign breas
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(6)
Human and experimental evidence indicates that the developing fetus may be more susceptible than the adult to the effects of certain carcinogens, including some polycyclic aromatic hydrocarbons (PAHs). Factors that can modulate susceptibility include
Autor:
J S, Jacobson, M D, Begg, L W, Wang, Q, Wang, M, Agarwal, E, Norkus, V N, Singh, T L, Young, D, Yang, R M, Santella
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(12)
Because their formation is associated with tumor development in specific tissues, DNA adducts have potential usefulness as intermediate end points in chemoprevention studies. To determine the efficacy of a combination of antioxidant vitamins (vitamin
Autor:
D G, Bostwick, E E, Alexander, R, Singh, A, Shan, J, Qian, R M, Santella, L W, Oberley, T, Yan, W, Zhong, X, Jiang, T D, Oberley
Publikováno v:
Cancer. 89(1)
Oxidative stress results in damage to cellular structures and has been linked to many diseases, including cancer. The authors sought to determine whether the expression of three major antioxidant enzymes, copper-zinc superoxide dismutase (SOD1), mang
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(2)
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants; a number are carcinogenic. Metabolic polymorphisms may modulate susceptibility to PAH-induced DNA damage and carcinogenesis. This study investigates the relationship bet
Publikováno v:
Cancer research. 59(23)
Crocidolite, one of the most carcinogenic forms of asbestos, is mutagenic in cultured mammalian cells when assayed using a system that can detect multilocus deletions. In the present study, we examined the effect of buthionine sulfoximine (BSO) on mu
Publikováno v:
The Journal of investigative dermatology. 113(6)
The use of psoralens combined with exposure to ultraviolet A radiation is a major form of treatment for psoriasis and a number of other common skin diseases. Although psoralen plus ultraviolet A treatment is highly effective, careful follow-up cohort