Výsledky vyhledávání - "R. M. Meloche"

Effect of cholinergic agonists on gastrin release from primary cultures of human antral G cells

Autor: I. Koop, Paul E. Squires, R. M. Meloche, Alison M.J. Buchan

Publikováno v: Gastroenterology. 112:357-363

BACKGROUND & AIMS: There is conflicting evidence concerning whether muscarinic regulation of gastrin release in humans is a direct or indirect effect on antral G cells. The present experiments were designed to resolve this question using an isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a948aa0d31d66b329bcf5876ed3d931
https://doi.org/10.1053/gast.1997.v112.pm9024289

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Signal transduction events involved in bombesin-stimulated gastrin release from human G cells in culture

Autor: Alison M.J. Buchan, R. M. Meloche

Publikováno v: Canadian Journal of Physiology and Pharmacology. 72:1060-1065

The mechanism of action of bombesin on human antral gastrin cells in culture was evaluated by modulating internal and external calcium levels and intracellular enzyme activities. Increasing extracellular calcium increased basal gastrin release and ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba01c67b74f4164ef2a9b6de33867a63
https://doi.org/10.1139/y94-148

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Release of somatostatin immunoreactivity from human antral D cells in culture

Autor: R. M. Meloche, Susan B. Curtis, Alison M.J. Buchan

Publikováno v: Gastroenterology. 99:690-696

A primary culture of human antral somatostatin cells has been developed and used in release studies. The phorbol ester, phorbol 12 myristate 13-acetate, caused a concentration-dependent increase in immunoreactive somatostatin secretion with a 1-mumol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e9a2ab83db1b8a38fc3fe7550da7af
https://doi.org/10.1016/0016-5085(90)90956-2

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Bombesin-evoked gastrin release and calcium signaling in human antral G cells in culture

Autor: Alison M.J. Buchan, Paul E. Squires, R. M. Meloche

Publikováno v: The American journal of physiology. 276(1)

Amplification of mRNA from a human antral cell culture preparation demonstrated the presence of two receptors of the bombesin and gastrin-releasing peptide family, GRPR-1 and BRS-3. Single cell microfluorometry demonstrated that most cells that exhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5407e8915817e77882dc2a7f37ea52a3
https://pubmed.ncbi.nlm.nih.gov/9887000

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L-type calcium channels regulate gastrin release from human antral G cells

Autor: R. M. Meloche, D. W. Nelson, J. M. Ray, T. P. Snutch, Paul E. Squires, Alison M.J. Buchan

Publikováno v: Scopus-Elsevier

In mRNA samples isolated from a gastrin (G) cell-enriched human antral cell preparation, reverse transcription-polymerase chain reaction identified products encoding part of the alpha 1-subunit of class C and D L-type voltage-dependent Ca2+ channels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611c7c5ef6057bd046ab5585b857e67f
https://pubmed.ncbi.nlm.nih.gov/9277405

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Cadaver kidney transplantation with minimal delayed function: experience with perioperative strategies to enhance initial renal allograft function

Autor: C R, Shackleton, P A, Keown, M G, McLoughlin, M K, Nigro, R M, Meloche, C H, Schudamore, A D, Manson, L M, Kane, J, Smart, E C, Cameron

Publikováno v: Transplantation proceedings. 27(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69a46269fe8f29b31ddaf8db0e010446
https://pubmed.ncbi.nlm.nih.gov/7878811

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Development of Helicobacter pylori-infected human antral primary cell cultures

Autor: R. M. Meloche, B. Brett Finlay, Agneta Richter-Dahlfors, Alison M.J. Buchan

Publikováno v: Gastroenterology. 114:A268

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4a9bdaf0d7c05a1b78ab16cdf088191
https://doi.org/10.1016/s0016-5085(98)81090-1

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Allotransplantation of culture-isolated neonatal rat islet tissue. Absence of MHC class II positive antigen-presenting cells in nonimmunogenic islets

Autor: C. R. Eide, J. R. Serie, R. J. Ketchum, R. M. Meloche, W. V. Moore, H. Popiela, Orion D. Hegre

Publikováno v: Diabetes. 38:146-151

When highly purified neonatal rat islet tissue, derived after 10 days in vitro, was allografted, it was found to be nonimmunogenic or weakly immunogenic. In contrast, nonislet pancreatic components, derived from the same culture system, transplanted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17af3e62a6e2ee8cb94572c2d6e387e7
https://doi.org/10.2337/diabetes.38.2.146

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Comparison of two canine pancreatic islet isolation techniques

Autor: J A, van der Vliet, D B, Kaufman, R M, Meloche, D E, Sutherland

Publikováno v: Transplantation proceedings. 21(1 Pt 3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42edf885e7dc37b7d97896f74c4ee50f
https://pubmed.ncbi.nlm.nih.gov/2495651

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Weight-corrected islet counts are predictive of outcome in the canine intrahepatic islet autograft model

Autor: S R, Munn, D B, Kaufman, R M, Meloche, M J, Field, D E, Sutherland

Publikováno v: Diabetes research (Edinburgh, Scotland). 9(3)

A combination of high-concentration collagenase digestion and density-gradient purification of canine pancreatic tissue made it possible to obtain relatively pure islets which could be quantified and the outcome of intrahepatic autotransplantation co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b21820734811f45f3e5fbdb2e9c60386
https://pubmed.ncbi.nlm.nih.gov/2854030

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