Zobrazeno 1 - 10
of 16
pro vyhledávání: '"R. M. Medford"'
Autor:
Robert Alexander, C P Hammes, R M Medford, C L Sundell, David G. Harrison, Jørn Bech Laursen, Pradyumna E. Tummala, Xi-Lin Chen
Publikováno v:
Circulation. 100:1223-1229
Background —Cardiovascular ischemic events may occur more frequently in hypertensive patients with activated renin-angiotensin systems. We tested the hypothesis that angiotensin II (Ang II) may contribute to atherosclerosis by increasing expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee363796c1998a1b8608d1602eb07e64
https://doi.org/10.1161/01.cir.100.11.1223
https://doi.org/10.1161/01.cir.100.11.1223
Publikováno v:
American Journal of Physiology-Renal Physiology. 266:F536-F542
We have found abnormalities in Na-K-adenosine-triphosphatase (Na-K-ATPase) function in different tissues of rats with chronic renal failure (CRF). A potential mechanism for these findings is a change in Na-K-ATPase alpha- and/or beta-gene expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f76e7f4994d2c75573ec5ce569ed664
https://doi.org/10.1152/ajprenal.1994.266.4.f536
https://doi.org/10.1152/ajprenal.1994.266.4.f536
Publikováno v:
Journal of Biological Chemistry. 268:15958-15964
Na/K-ATPase in renal epithelium is expressed at the basolateral surface and thus is critical for vectorial solute transport. One potential mode of regulation of Na/K-ATPase involves the intracellular effector protein kinase C (PKC). In kidney cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8133d095d037f646829affd896fd42c
https://doi.org/10.1016/s0021-9258(18)82345-6
https://doi.org/10.1016/s0021-9258(18)82345-6
Publikováno v:
Circulation Research. 69:39-44
Total RNA isolated from canine saphenous vein smooth muscle cells was examined for Na+ pump alpha- and beta-mRNA content by three increasingly sensitive methods: Northern analysis, RNase protection assay, and polymerase chain reaction. Northern analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a14758a1bb4999ded38fda445931bb4
https://doi.org/10.1161/01.res.69.1.39
https://doi.org/10.1161/01.res.69.1.39
Publikováno v:
Diabetes. 48(4)
The transcriptional nuclear factor (NF)-kappaB can be activated by diverse stimuli such as cytokines, mitogens, oxidative stress, and lipids, leading to the transactivation of several genes that play important roles in the development of atherosclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea203e9eeaead6db47fa3f492fbeb98
https://pubmed.ncbi.nlm.nih.gov/10102704
https://pubmed.ncbi.nlm.nih.gov/10102704
Publikováno v:
Annals of the New York Academy of Sciences. 834
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44ce20048efe284f36941d9cd08ff2e8
https://pubmed.ncbi.nlm.nih.gov/9405844
https://pubmed.ncbi.nlm.nih.gov/9405844
Publikováno v:
The American journal of physiology. 266(2 Pt 2)
Na-K-ATPase is a heterodimeric complex composed of an alpha-catalytic and a glycosylated beta-subunit. Previous studies using in situ hybridization and Northern blot analysis to determine alpha- and beta-subunit mRNA isoform expression in the rat kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b190154e1c1deef0ade63336bce8f96a
https://pubmed.ncbi.nlm.nih.gov/8141325
https://pubmed.ncbi.nlm.nih.gov/8141325
Autor:
M K, Offermann, R M, Medford
Publikováno v:
Heart disease and stroke : a journal for primary care physicians. 3(1)
Current models of atherogenesis link abnormalities in the oxidative state of the vascular wall with interactions with the immune system, leading to a cycle of localized inflammatory and growth responses that result in the characteristics of the matur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::978d35e711b3ed0e4eb5799d5f6f7b40
https://pubmed.ncbi.nlm.nih.gov/7511030
https://pubmed.ncbi.nlm.nih.gov/7511030
Autor:
Keiji Yamamoto, Yoshio Tsuruya, Kiyoshi Kawakami, Kazuyuki Shimada, Toshiko Kanbe, Uichi Ikeda, R. M. Medford, A. Oguchi
Publikováno v:
The American journal of physiology. 265(4 Pt 2)
Na-K-adenosinetriphosphatase (ATPase) activity profoundly influences vascular cell excitability, contractility, and volume regulation. The recent finding of mineralocorticoid hormone receptors in vascular tissue suggests the possibility that Na-K-ATP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7e8554693502eff3c2b3cea2d9786a
https://pubmed.ncbi.nlm.nih.gov/8238401
https://pubmed.ncbi.nlm.nih.gov/8238401
Publikováno v:
The Journal of biological chemistry. 268(21)
Na/K-ATPase in renal epithelium is expressed at the basolateral surface and thus is critical for vectorial solute transport. One potential mode of regulation of Na/K-ATPase involves the intracellular effector protein kinase C (PKC). In kidney cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c023296358b5b761976f457ec30029cd
https://pubmed.ncbi.nlm.nih.gov/8393456
https://pubmed.ncbi.nlm.nih.gov/8393456