Zobrazeno 1 - 10
of 19
pro vyhledávání: '"R. M. Lyons"'
Autor:
D. J. Kuter, J. B. Bussel, A. Newland, R. I. Baker, R. M. Lyons, J. Wasser, J.-F. Viallard, G. Macik, M. Rummel, K. Nie, S. Jun
Publikováno v:
Онкогематология, Vol 9, Iss 3, Pp 47-62 (2015)
Romiplostim was effective, safe, and well-tolerated over 6–12 months of continuous treatment in Phase 3 trials in patients with immune thrombocytopenia (ITP). This report describes up to 5 years of weekly treatment with romiplostim in 292 adult ITP
Externí odkaz:
https://doaj.org/article/661feac80d794582bcdbb8c8690857d3
Autor:
H I, Bussey, R M, Lyons
Publikováno v:
Pharmacotherapy. 18(3)
Current anticoagulation guidelines for patients with mechanical heart valves are based on studies that are seriously flawed in that they used prothrombin time ratios rather than the international normalized ratio (INR) and failed to consider the leve
Autor:
R M, Lyons, S, Forry-Schaudies, E, Otto, C, Wey, V, Patil-Koota, M, Kaloss, G J, McGarrity, Y L, Chiang
Publikováno v:
Cancer gene therapy. 2(4)
Brain tumors have been treated clinically by intratumoral injection of cells that produce retroviral vectors encoding the herpes simplex virus thymidine kinase (HSV-TK) gene followed by systemic administration of the antiviral drug ganciclovir. In vi
Autor:
T E, Spiro, G J, Johnson, M J, Christie, R M, Lyons, D E, MacFarlane, R B, Blasier, M D, Tremaine
Publikováno v:
Annals of internal medicine. 121(2)
To determine the most effective and safe dose of enoxaparin to prevent deep venous thrombosis in high-risk surgical patients.A double-blind, randomized, multicenter clinical trial.Private, university, and government hospitals in the United States.572
Autor:
R. D. Beauchamp, R. M. Lyons, Hong-Miao Sheng, H. L. Moses, G. Torre-Amione, D. A. Miller, C. C. Bascom
Publikováno v:
Endocrinology. 130(5)
Mouse embryo-derived AKR-2B fibroblasts and murine fibrosarcoma cells (the 1591 cell line) were transfected with a murine transforming growth factor-beta 1 (TGF beta 1) cDNA under the transcriptional control of either the simian virus-40 early promot
Publikováno v:
Cancer research. 51(19)
A serotonin-secreting human pancreatic carcinoid cell line (BON) is demonstrated to express transcripts for all three mammalian types of transforming growth factor beta (TGF beta 1, 2, and 3). Similarly, freshly excised carcinoid tumors from six pati
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 1(8)
Exogenous TGF beta inhibits the proliferation of human breast cancer cells in vitro. These cells synthesize and secrete TGF beta into their medium predominantly in a latent form. With neutralizing antibodies against native, biologically active TGF be
Autor:
H. L. Moses, Nancy J. Sipes, R. W. Pelton, R. D. Beauchamp, J. A. Pietenpol, C. C. Bascom, J. A. Barnard, R. M. Lyons, D. A. Miller, Edmund Y. Yang
Publikováno v:
New Concepts in Cancer ISBN: 9781349106738
The transforming growth factors (TGF) were originally described as autocrine factors thought to be involved in neoplastic transformation, and were defined by their biologic effects on fibroblastic cells. These effects include stimulation of colony fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4499b716933f06b3f9518a0e70dbdc
https://doi.org/10.1007/978-1-349-10671-4_16
https://doi.org/10.1007/978-1-349-10671-4_16
Publikováno v:
Journal of Thrombosis and Haemostasis. 1:OC194-OC194
Publikováno v:
Journal of Clinical Investigation. 80:750-757
Transforming growth factor beta (TGF beta), a recently discovered polypeptide, modulates growth of normal and neoplastic cells. Since little is known concerning in vivo disposition of TGF beta, we performed studies to examine the hepatic processing o