Zobrazeno 1 - 10
of 16
pro vyhledávání: '"R. M. Haigh"'
Publikováno v:
Journal of Molecular Endocrinology. 5:185-188
Glucocorticoids are known to influence cardiovascular sensitivity to catecholamines but the molecular mechanisms are undefined. We recently showed that glucocorticoids control the coupling of adrenergic receptors to G protein. Alterations in the amou
Publikováno v:
Arzneimittel-Forschung. 46(8)
The effects after oral administration of the angiotensin II antagonist telmisartan (CAS 144701-48-4, BIBR 227) on arterial blood pressure and heart rate of conscious chronically-instrumented TGR (mREN2)27 transgenic rats were studied. Each dose of te
Publikováno v:
Arzneimittel-Forschung. 45(2)
The effects of the cardiotonic agent pimobendan (CAS 118428-36-7, UD-CG 115 BS) and its main metabolite UD-CG 212 on dog cardiac myofibrillar calcium responsiveness and ATPase activity were studied at nominal free inorganic phosphate (Pi) and at 5 mm
Autor:
R. M. Haigh, C. T. Jones
Publikováno v:
Journal of molecular endocrinology. 5(1)
Glucocorticoids are known to have marked effects on blood pressure regulation, predominantly through altering cardiovascular sensitivity to noradrenaline. However, the molecular mechanisms underlying this action remain unclear. As part of our studies
Autor:
T. H. Corn, J. R. M. Haigh
Publikováno v:
Early Phase Drug Evaluation in Man ISBN: 9781349107070
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac4e00d06315dd2b24a2b2c22ee1e92
https://doi.org/10.1007/978-1-349-10705-6_35
https://doi.org/10.1007/978-1-349-10705-6_35
Autor:
D. N. Joanes, J. R. M. Haigh, G. M. Tate, M. P. Feely, S. Kumar, M. Boothby, J. A. Davies, B. E. Roberts
Publikováno v:
British journal of haematology. 74(1)
There is a discrepancy in the results of reported studies of levels of vitamin K dependent coagulation factors in patients on warfarin therapy. This may have arisen partly because of the problem of assuring compliance with therapy in outpatients. The
Publikováno v:
Journal of Endocrinology. 133:405-NP
Glucocorticoids are known to regulate the contractility of vascular smooth muscle by increasing its response to noradrenaline. The molecular mechanisms for achieving this remain unclear. Recent results in our laboratory have demonstrated that glucoco
Autor:
L. Micklewright, H. Gregory, M. Holltngsworth, S. J. Butler, Stephen W D'Souza, P. Donnai, R.D.H. Boyd, R. M. Haigh
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 96:171-178
Summary. Urogastrone was measured by radioimmunoassay in amniotic fluid obtained from 186 complicated pregnancies at 22 to 40 weeks gestation. Amniocentesis was performed for a variety of indications to obtain information about fetal lung maturity or
Publikováno v:
Psychopharmacology. 98:487-494
The muscarinic antagonist scopolamine and the benzodiazepine lorazepam both produce transient impairments in memory and attention in normal volunteers. These impairments can be reversed by appropriate agents such as the cholinesterase inhibitor physo
Publikováno v:
British Journal of Clinical Pharmacology. 25:755-757
The effect of 5 days treatment with allopurinol (300 mg) on the pharmacokinetics of indomethacin at steady-state was investigated in eight patients. Allopurinol produced no significant effect on the indomethacin serum concentration-time curve. Allopu