Zobrazeno 1 - 10
of 140
pro vyhledávání: '"R. M. Gogal"'
Publikováno v:
Journal of Small Animal Practice.
Autor:
R. M. Gogal, Steven D. Holladay
Publikováno v:
Journal of Immunotoxicology. 5:413-418
Modulation of the developing immune system can occur following perinatal exposure to a number of immunotoxic compounds, including polyhalogenated hydrocarbons like 2,3,7,8-tetra-chlorodibenzo-p-dioxin (TCDD; dioxin), the most toxic of the congeners.
Publikováno v:
Immunological Investigations. 34:71-89
Publikováno v:
Critical Reviews in Toxicology. 35:299-302
Autor:
L. J. Hart R. M. Gogal
Publikováno v:
Toxic Substance Mechanisms. 18:21-38
Tilapia (Oreochromis niloticus) were subacutely exposed to the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) by intraperitoneal injection of 1 or 5 mug/kg/day for five consecutive days. Cellularity and morphology of the spleen
Publikováno v:
Immunological investigations. 34(1)
The magnitude of an immune response to many foreign and/or self-antigens is known to be gender-dependent and influenced by sex hormones. While the immune consequences of long-term exposure (3 to 5 months) to natural 17-beta estradiol in an inbred mou
Publikováno v:
Teratology. 62(6)
Maternal immune stimulation has reported, but unconfirmed, efficacy for reducing chemical-induced morphologic defects in mice.Teratogenic chemicals (2,3,7, 8-tetrachlorodibenzo-p-dioxin [TCDD], ethyl carbamate [urethane], methylnitrosourea [MNU], or
Publikováno v:
Teratology. 62(6)
Maternal immune stimulation reduces malformations caused by chemical teratogens. Mechanisms for this effect are not known. Altered expression of regulatory molecules (e.g., transforming growth factor [TGF-beta], tumor necrosis factor-alpha [TNF-alpha
Publikováno v:
Cytometry. 39(4)
Chemical induction of apoptosis in cells is believed to contribute to toxicity. Techniques for measuring apoptosis have increased in both sensitivity and number and in many cases can be readily extended to nontraditional research species. A compariso
Publikováno v:
Avian diseases. 41(3)
An assessment of T-cell-mediated immune functions (i.e., lymphocyte proliferation assay) in the chicken, unlike the determination of antibody levels, is not routinely performed. This is primarily because of difficulties in the isolation of relatively