Výsledky vyhledávání

Impact of Daratumumab on Stem Cell Collection, Graft Composition and Engraftment Among Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplant

Autor: Ehsan Malek, Merle Kolk, R. M. Fox, James J. Driscoll, Paolo Caimi, Shivaprasad Manjappa, Amin Firoozamand, Marcos de Lima, Jane S. Reese, Hannah Schmikla, Savannah Nall

Publikováno v: Blood. 136:35-37

Background High dose chemotherapy followed by autologous stem cell transplantation (ASCT) plays an important role in the treatment of transplant-eligible multiple myeloma (MM) patients and yields deep responses, prolongs progression-free survival (PF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::116e6d64d31ee851aea6f6cbca6aae6d
https://doi.org/10.1182/blood-2020-142115

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Cryopreservation of hematopoietic cells using a pre-constituted, protein-free cryopreservative solution with 5% dimethyl sulfoxide

Autor: Jane Reese Koc, R. M. Fox, Marcos de Lima, Folashade Otegbeye, Tabatha Trummer

Publikováno v: Cytotherapy. 22(11)

Background aims Adequate cryopreservation techniques are critical to ensure optimal recovery of functional progenitor cells in hematopoietic cell (HC) transplantation, minimize risk of contamination and prevent infusion-related adverse events (irAEs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403c8fbfd4978cf317282d91a03a9f9f
https://pubmed.ncbi.nlm.nih.gov/32600975

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Whole-Exome Sequencing Identifies a Somatic Cell Mutation Signature That Predicts Relapse Risk and Survival Probability in Multiple Myeloma

Autor: Marcos de Lima, Jane S. Reese, Byung-Gyu Kim, Paolo Caimi, James J. Driscoll, Ehsan Malek, R. M. Fox, Daniel Qu, E. Ricky Chan

Publikováno v: Blood. 136:5-5

Introduction: Multiple myeloma (MM) is a plasma cell neoplasm associated with heterogeneous somatic alterations. Despite the development of novel anti-myeloma agents that have significantly prolonged patient survival, disease relapse remains a daunti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84bc1d07f74aa9f7ed96782df77e6c68
https://doi.org/10.1182/blood-2020-142791

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Manufacturing A Donor Lymphocyte Product Depleted Of TCR-αβ T Cells And CD19+ B Cells For Prophylactic Infusion Following Allogeneic Stem Cell Transplantation

Autor: T.L. Turney, M. Garcia, C. Ramsey, Folashade Otegbeye, Jane Reese-Koc, R. M. Fox, M. de Lima, Howard J. Meyerson

Publikováno v: Cytotherapy. 22:S134

Background & Aim Background In allogeneic stem cell transplantation (HSCT), relapse of hematologic malignancies is a leading cause of post-transplant morbidity. In the early post-transplant period, when immune reconstitution is pending, residual leuk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28059ba68553921d09558ac46d8676e6
https://doi.org/10.1016/j.jcyt.2020.03.262

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Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis

Autor: Brittney M Hooper, Kylie M Drake, Peter B. Imrey, Basabi Maitra, Micheala A. Aldred, Jane Reese Koç, Sarah M. Planchon, Karen Lingas, Hillard M. Lazarus, R. M. Fox, Jeffrey A. Cohen

Publikováno v: Multiple Sclerosis Journal-Experimental, Translational and Clinical

Background Multiple sclerosis is an inflammatory, neurodegenerative disease of the central nervous system for which therapeutic mesenchymal stem cell transplantation is under study. Published experience of culture-expanding multiple sclerosis patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dad7a0490622e38a2ee3c8c15cc36fe
https://pubmed.ncbi.nlm.nih.gov/29623216

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Presence of Chip-Mutated Autologous Hematopoietic Cells in Mobilized Peripheral Blood Products Is Associated with Shorter Progression-Free Survival after Autologous Transplants for Multiple Myeloma

Autor: R. M. Fox, Ehsan Malek, Sowjanya Vuyyala, Hannah Schmikla, James J. Driscoll, Petra Martin, Marcos de Lima, Navid Sadri, Paolo Caimi, Benjamin Tomlinson, Michael D. Caldwell, Gayathri Ravi

Publikováno v: Blood. 134:515-515

Multiple Myeloma (MM) remains a cancer of terminally-differentiated plasma cells that reside predominantly within the bone marrow. Malignant plasma cells are nurtured by a permissive microenvironment that favors tumor progression, drug resistance and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3169d4b24f6bc1f822063554b9e727c
https://doi.org/10.1182/blood-2019-127335

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Microbial contamination of hematopoietic progenitor and other regenerative cells used in transplantation and regenerative medicine

Autor: Hillard M. Lazarus, R. M. Fox, Katharine P. Roman, Michael R. Jacobs, Caryn E. Good

Publikováno v: Transfusion. 53:2690-2696

Background Microbial contamination of hematopoietic progenitor cells (HPCs) and other regenerative cells used in transplantation and regenerative medicine can occur during collection and after in vitro manipulation, including purging, cryopreservatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c4508279a216667f12063f3d0578462
https://doi.org/10.1111/trf.12150

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Investigation of Occult Hip Fractures: The Use of CT and MRI

Autor: R M Fox, T. J. S. Chesser, J. Smith, S. K. Gill

Publikováno v: The Scientific World Journal, Vol 2013 (2013)
The Scientific World Journal

Aim. At present there is no data looking at modern multislice computerised tomography (CT) in the investigation of occult hip fracture. The aim of this study was to retrospectively compare the reports of patients sent for magnetic resonance imaging (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5713bd328e4949fe3df7b8732b2dfe5
https://doi.org/10.1155/2013/830319

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Influence of human leucocyte antigen disparity and graft lymphocytes on allogeneic engraftment and survival after umbilical cord blood transplant in adults

Autor: Hillard M. Lazarus, Marcie R. Finney, Willem J. van Heeckeren, Jennifer Jaroscak, R. M. Fox, Pingfu Fu, Tamila L. Kindwall-Keller, Richard J. Creger, Luis A. Solchaga, L.R. Fanning, William Tse, Mary J. Laughlin, Brenda W. Cooper, Howard J. Meyerson, Margaret Forster

Publikováno v: British Journal of Haematology. 139:464-474

The dose of graft-nucleated cells and CD34(+) haematopoietic progenitor cells are predictors of allogeneic engraftment and survival in umbilical cord blood (UCB) recipients. In this single institution prospective phase II trial, flow cytometric analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::794d17b0474eb87a43def699f35347b8
https://doi.org/10.1111/j.1365-2141.2007.06824.x

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Comparison of 2 Carmustine-Containing Regimens in the Rituximab Era: Excellent Outcomes Even in Poor-Risk Patients

Autor: Carlos H. Silva Rondon, Brenda W. Cooper, Hillard M. Lazarus, Erica L. Campagnaro, Marcos de Lima, Jane Reese-Koc, Basem M. William, Paolo Caimi, Richard J. Creger, Pingfu Fu, R. M. Fox, Stanton L. Gerson

Publikováno v: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(11)

High-dose chemotherapy followed by autologous hematopoietic cell transplantation (HCT) improves outcomes in relapsed lymphoma, but the relative efficacy of different preparative regimens is not well defined. We included patients undergoing autologous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c4be1a4bb1530e98b5841cf2d81a7e
https://pubmed.ncbi.nlm.nih.gov/26087475

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