Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R. M. E. Chalmers-Redman"'
Autor:
S. L. Shankar, A.C. Cuello, R. M. E. Chalmers-Redman, Moshe Szyf, Susan M. Grant, W. G. Tatton
Publikováno v:
NeuroReport. 10:41-46
Metabolic hypofunction is a common finding in a number of neurodegenerative diseases, including Alzheimer's disease (AD). The strong linkage between the amyloid precursor protein (APP) and AD led us to examine whether over-expression of this protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b51ffbc6fee037d1bddcaf9def0c69
https://doi.org/10.1097/00001756-199901180-00008
https://doi.org/10.1097/00001756-199901180-00008
Autor:
Jehangir Wadia, Graeme W. Carlile, R. M. E. Chalmers-Redman, William G. Tatton, A. D. Fraser, W. J. H. Ju, J. L. Phillips
Publikováno v:
The Journal of Neuroscience. 18:932-947
Studies in non-neural cells have suggested that a fall in mitochondrial membrane potential (ΔΨM) is one of the earliest events in apoptosis. It is not known whether neural apoptosis caused by nerve growth factor (NGF) and serum withdrawal involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39632ed9c6d50d12aa1f7ed301be0b60
https://doi.org/10.1523/jneurosci.18-03-00932.1998
https://doi.org/10.1523/jneurosci.18-03-00932.1998
Autor:
A. W. Pong, William G. Tatton, N. A. Tatton, Graeme W. Carlile, M. Mammen, R. M. E. Chalmers-Redman, W. J. H. Ju
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 301(2)
(-)-Deprenyl and structurally related propargylamines increase neuronal survival independently of monoamine oxidase B (MAO-B) inhibition, in part by decreasing apoptosis. We found that deprenyl and two other propargylamines, one of which does not inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236830558f883da3e33aca0e30ce0a54
https://pubmed.ncbi.nlm.nih.gov/11961082
https://pubmed.ncbi.nlm.nih.gov/11961082
Publikováno v:
Advances in Research on Neurodegeneration ISBN: 9783211829349
Apoptotic, rather than necrotic, nerve cell death now appears as likely to underlie a number of common neurological conditions including stroke, Alzheimer’s disease, Parkinson’s disease, hereditary retinal dystrophies and Amyotrophic Lateral Scle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beee512461fa66d24d3bec7871f571a1
https://doi.org/10.1007/978-3-7091-6844-8_25
https://doi.org/10.1007/978-3-7091-6844-8_25
Publikováno v:
Deprenyl — Past and Future ISBN: 9783211828915
(−)-Deprenyl stereospecifically reduces neuronal death even after neurons have sustained seemingly lethal damage at concentrations too small to cause monoamine oxidase-B (MAO-B) inhibition. (−)-Deprenyl can also influence the process growth of so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ca28e23baaf09714afc331bfe28d29e
https://doi.org/10.1007/978-3-7091-7494-4_5
https://doi.org/10.1007/978-3-7091-7494-4_5
Autor:
R. M. E. Chalmers-Redman, William G. Tatton, W. Y. H. Ju, A. D. Fraser, Jehangir Wadia, N. A. Tatton
Publisher Summary Nerve cell death in human stroke was believed to be necrotic. In the 1970s and early 1980s, evidence of a different form of cell death termed “apoptosis” was found. Apoptosis seemed particularly important as a counterbalance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec70c8300fcf7e0bf0efce879bf534c
https://doi.org/10.1016/s0074-7742(08)60713-8
https://doi.org/10.1016/s0074-7742(08)60713-8