Zobrazeno 1 - 10 of 44 pro vyhledávání: '"R. M. Denton"'
1
Philip John Randle - Bibliography from Philip John Randle. 16 July 1926—26 September 2006
Autor: S. J. H. Ashcroft, R. M. Denton
Sir Philip Randle, who died aged 80 on 26 September 2006 after a brief illness, was one of the world's foremost researchers into mammalian metabolism. In a career spanning some five decades, he provided a series of brilliant insights into the fundame
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6761399af3f6e0ba64fca0940ac0336c
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2
Baculovirus-directed expression of the human insulin receptor and an insulin-binding ectodomain
Autor: R M Denton, J. M. Tavare, J I Paul, Donald F. Steiner
Publikováno v: Journal of Biological Chemistry. 265:13074-13083
In this report we describe the use of the baculovirus expression system to overproduce the human insulin holoreceptor (HIR) and a truncated, secretory version of the HIR cDNA (HIRsec) consisting of the alpha subunit and the extracellular portion of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52ff2ffa796404b8a015e4ef9a7d58a7
https://doi.org/10.1016/s0021-9258(19)38269-9
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3
Mitochondrial Ca2+ transport and the role of intramitochondrial Ca2+ in the regulation of energy metabolism
Autor: J G, McCormack, R M, Denton
Publikováno v: Developmental neuroscience. 15(3-5)
The mitochondrial inner membrane of all mammalian tissues, including brain tissues, has specific active transport systems for the uptake and egress of Ca2+. The primary role of this transport system is to relay changes in cytosolic [Ca2+], which stim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b58a3a41b65f64d0bc6b55140cbb05fe
https://pubmed.ncbi.nlm.nih.gov/7805568
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5
Baculovirus-directed expression of the human insulin receptor and an insulin-binding ectodomain
Autor: J I, Paul, J, Tavaré, R M, Denton, D F, Steiner
Publikováno v: The Journal of biological chemistry. 265(22)
In this report we describe the use of the baculovirus expression system to overproduce the human insulin holoreceptor (HIR) and a truncated, secretory version of the HIR cDNA (HIRsec) consisting of the alpha subunit and the extracellular portion of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46ff0ab74f0ddef71a24fd1198b8feb3
https://pubmed.ncbi.nlm.nih.gov/2198283
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6
The effects of glucagon, phenylephrine and insulin on the phosphorylation of cytoplasmic, mitochondrial and membrane-bound proteins of intact liver cells from starved rats
Autor: A M Vargas, R M Denton, A P Halestrap
Publikováno v: Biochemical Journal. 208:221-229
1. The effects of glucagon, insulin and phenylephrine on the phosphorylation of cytoplasmic, mitochondrial and membrane proteins were studied in intact hepatocytes from 24 h-starved rats incubated with [32P]Pi. A rapid cell-fractionation technique wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839395cadc47b37c3304af56e6e8142e
https://doi.org/10.1042/bj2080221
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7
Properties of N-maleoylmethionine sulphone, a novel impermeant maleimide, and its use in the selective labelling of the erythrocyte glucose-transport system
Autor: R M Denton, M J A Tanner, S J Roberts
Publikováno v: Biochemical Journal. 205:139-145
1. The synthesis of N-maleoylmethionine sulphone (MMS), a membrane-impermeant protein-labelling reagent, is described. Radioactively labelled MMS can be readily prepared at high specific radioactivity from [35S]methionine. 2. The permeability of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a645d1134dce79f1f98d109bed149034
https://doi.org/10.1042/bj2050139
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8
Evidence that fatty acid synthesis in the interscapular brown adipose tissue of cold-adapted rats is increased in vivo by insulin by mechanisms involving parallel activation of pyruvate dehydrogenase and acetyl-coenzyme A carboxylase
Autor: R M Denton, J G McCormack
Publikováno v: Biochemical Journal. 166:627-630
Plasma insulin concentrations in cold-adapted rats were altered acutely by administration of glucose or anti-insulin serum. Rates of fatty acid synthesis in interscapular brown adipose tissue were determined from the incorporation of 3H from 3H2O int
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe80dc044c67ce627831015d16ac0e4f
https://doi.org/10.1042/bj1660627
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9
Persistence of the effect of insulin on pyruvate dehydrogenase activity in rat white and brown adipose tissue during the preparation and subsequent incubation of mitochondria
Autor: J G McCormack, R M Denton, S E Marshall
Publikováno v: Biochemical Journal. 217:441-452
Increases in the amount of the active non-phosphorylated form of pyruvate dehydrogenase in rat epididymal adipose tissue, as a result of incubation with insulin, persist not only during the preparation of mitochondria but also during subsequent incub
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f3b6f0f93053359a50c2c0fccab5c7
https://doi.org/10.1042/bj2170441
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