Zobrazeno 1 - 10
of 911
pro vyhledávání: '"R. Lowy"'
Autor:
Jaimie Z. Shing, Carolina Porras, Maísa Pinheiro, Rolando Herrero, Allan Hildesheim, Danping Liu, Mitchell H. Gail, Byron Romero, John T. Schiller, Michael Zúñiga, Sambit Mishra, Laurie Burdette, Kristine Jones, John Schussler, Rebeca Ocampo, Jianwen Fang, Zhiwei Liu, Douglas R. Lowy, Sabrina H. Tsang, Ana Cecilia Rodríguez, Mark Schiffman, Cameron B. Haas, Loretto J. Carvajal, Jalen R. Brown, Aimée R. Kreimer, Lisa Mirabello, Costa Rica HPV Vaccine Trial (CVT) Group
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract The AS04-adjuvanted human papillomavirus (HPV)16/18 vaccine, an L1-based vaccine, provides strong vaccine efficacy (VE) against vaccine-targeted type infections, and partial cross-protection to phylogenetically-related types, which may be af
Externí odkaz:
https://doaj.org/article/34f39d3bc9f746019ec00687f85c2a66
Autor:
Ulrik Ringborg, Joachim vonBraun, Julio Celis, Michael Baumann, Anton Berns, Alexander Eggermont, Edith Heard, Manuel Heitor, Mammen Chandy, Chien‐Jen Chen, Alberto Costa, Francesco De Lorenzo, Edward M. De Robertis, Frederick Charles Dubee, Ingemar Ernberg, Mariya Gabriel, Åslaug Helland, Rui Henrique, Bengt Jönsson, Olli Kallioniemi, Jan Korbel, Mechthild Krause, Douglas R. Lowy, Olivier Michielin, Peter Nagy, Simon Oberst, Vincenzo Paglia, M. Iqbal Parker, Kevin Ryan, Charles L. Sawyers, Joachim Schüz, Katherine Silkaitis, Eric Solary, David Thomas, Peter Turkson, Elisabete Weiderpass, Huanming Yang
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 245-279 (2024)
Analyses of inequalities related to prevention and cancer therapeutics/care show disparities between countries with different economic standing, and within countries with high Gross Domestic Product. The development of basic technological and biologi
Externí odkaz:
https://doaj.org/article/aed58f51906b40f3875630c0b7d33c89
Autor:
Lulu Yu, Vladimir Majerciak, Alexei Lobanov, Sameer Mirza, Vimla Band, Haibin Liu, Maggie Cam, Stephen H. Hughes, Douglas R. Lowy, Zhi-Ming Zheng
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTThe integration of HPV DNA into human chromosomes plays a pivotal role in the onset of papillomavirus-related cancers. HPV DNA integration often occurs by linearizing the viral DNA in the E1/E2 region, resulting in the loss of a critical vira
Externí odkaz:
https://doaj.org/article/c388e3f748c7460a94678b0646a8cfb1
Autor:
Jimmie L. Bullock, Thomas E. Hickey, Troy J. Kemp, Jordan Metz, Sarah Loftus, Katarzyna Haynesworth, Nicholas Castro, Brian T. Luke, Douglas R. Lowy, Ligia A. Pinto
Publikováno v:
Vaccines, Vol 12, Iss 5, p 516 (2024)
SARS-CoV-2 vaccination-induced protection against infection is likely to be affected by functional antibody features. To understand the kinetics of antibody responses in healthy individuals after primary series and third vaccine doses, sera from the
Externí odkaz:
https://doaj.org/article/b574eefbdb0844ac8003e7d86aab8806
Autor:
Thomas E. Hickey, Troy J. Kemp, Jimmie Bullock, Aaron Bouk, Jordan Metz, Abigail Neish, James Cherry, Douglas R. Lowy, Ligia A. Pinto
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 2 (2023)
Certain aspects of the immunogenicity and effectiveness of the messenger ribonucleic acid (mRNA) vaccines (mRNA-1273 and BNT162b2) developed in response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are still uncharacte
Externí odkaz:
https://doaj.org/article/0a66c134f1764754ac6c6d4cd549e4a5
Autor:
Troy J. Kemp, Heidi A. Hempel, Yuanji Pan, Daisy Roy, James Cherry, Douglas R. Lowy, Ligia A. Pinto
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The Coronavirus disease 2019 (COVID-19) pandemic presented the scientific community with an immediate need for accurate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serology assays, resulting in an expansion of assay developm
Externí odkaz:
https://doaj.org/article/0409953055044e7b8f18e057f95c980f
Autor:
Sabrina H. Tsang, John T. Schiller, Carolina Porras, Troy J. Kemp, Rolando Herrero, John Schussler, Monica S. Sierra, Bernal Cortes, Allan Hildesheim, Douglas R. Lowy, Ana Cecilia Rodríguez, Byron Romero, Nicolas Çuburu, Jaimie Z. Shing, Ligia A. Pinto, Joshua N. Sampson, Aimée R. Kreimer, on behalf of the Costa Rica HPV Vaccine Trial Group
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract The HPV vaccine has shown sustained efficacy and consistent stabilization of antibody levels, even after a single dose. We defined the HPV16-VLP antibody avidity patterns over 11 years among women who received one- or three doses of the biva
Externí odkaz:
https://doaj.org/article/d8d0fcb1cc4f4e61b568dfc53679c2e8
Autor:
Brajendra K. Tripathi, Meghan F. Anderman, Disha Bhargava, Luciarita Boccuzzi, Xiaolan Qian, Dunrui Wang, Marian E. Durkin, Alex G. Papageorge, Fernando J. de Miguel, Katerina Politi, Kylie J. Walters, James H. Doroshow, Douglas R. Lowy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The tumor suppressor gene DLC1 can be downregulated in cancers through genetic and non-genetic mechanisms. Here, the authors show cytoplasmic EZH2 can directly methylate and destabilize the DLC1 protein, and EZH2 inhibition can increase the DLC1 prot
Externí odkaz:
https://doaj.org/article/7176f11d2bb2458e8f04d65843a147be
Autor:
Beatriz Sanchez-Solana, Dunrui Wang, Xiaolan Qian, Parthibane Velayoudame, Dhirendra K. Simanshu, Jairaj K. Acharya, Douglas R. Lowy
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-18 (2021)
Abstract Background DLC1, a tumor suppressor gene that is downregulated in many cancer types by genetic and nongenetic mechanisms, encodes a protein whose RhoGAP and scaffolding activities contribute to its tumor suppressor functions. The role of the
Externí odkaz:
https://doaj.org/article/a367e3987a09471bbf53fecd07797e4f
Autor:
Ligia A. Pinto, Ribhi M. Shawar, Brendan O’Leary, Troy J. Kemp, James Cherry, Natalie Thornburg, Cheryl N. Miller, Pamela S. Gallagher, Timothy Stenzel, Brittany Schuck, S. Michele Owen, Marina Kondratovich, Panayampalli S. Satheshkumar, Amy Schuh, Sandra Lester, M. Cristina Cassetti, Norman E. Sharpless, Steven Gitterman, Douglas R. Lowy
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The emergence of SARS-CoV-2 created a crucial need for serology assays to detect anti-SARS-CoV-2 antibodies, which led to many serology assays entering the market. A trans-government collaboration was created in April 2020 to independently e
Externí odkaz:
https://doaj.org/article/fd1d888a005e451da19462a26970c706