Výsledky vyhledávání

Human T-Cell Response to Meningococcal Immunoglobulin A1 Protease Associated alpha-Proteins

Autor: Dirk R. Lorenzen, Thomas F. Meyer, Uwe Wölk, H. Wenschuh, Joachim Jose

Publikováno v: Scandinavian Journal of Immunology

A unique feature of the immunoglobulin A1 (IgA1) protease from pathogenic Neisseriae, i.e. N. meningitidis and N. gonorrhoeae, is its co-secretion with an amphipathic α-protein. Polymerase chain reaction (PCR) analysis of the respective igaα gene r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3def28b5bec80475b25a0c563a0820f8
https://doi.org/10.1046/j.1365-3083.2000.00670.x

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Immunoglobulin A1 Protease, an Exoenzyme of Pathogenic Neisseriae, Is a Potent Inducer of Proinflammatory Cytokines

Autor: Anastasios Tsirpouchtsidis, Frank Düx, Gaby Haas, Uwe Wölk, Thomas F. Meyer, Dirk R. Lorenzen

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine

A characteristic of human pathogenic Neisseriae is the production and secretion of an immunoglobulin (Ig)A1-specific serine protease (IgA1 protease) that cleaves preferentially human IgA1 and other target proteins. Here we show a novel function for n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff536f522a1c2753fc79bf1eced8f8b
https://doi.org/10.1084/jem.190.8.1049

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Specific In Vivo Labeling of Cell Surface-Exposed Protein Loops: Reactive Cysteines in the Predicted Gating Loop Mark a Ferrichrome Binding Site and a Ligand-Induced Conformational Change of the Escherichia coli FhuA Protein

Autor: Dirk R. Lorenzen, Volkmar Braun, Christoph Bös

Publikováno v: Journal of Bacteriology. 180:605-613

The FhuA protein of Escherichia coli K-12 transports ferrichrome, the antibiotic albomycin, colicin M, and microcin 25 across the outer membrane and serves as a receptor for the phages T1, T5, φ80, and UC-1. FhuA is activated by the electrochemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc358b4fdc71a5f9024930234d16e78
https://doi.org/10.1128/jb.180.3.605-613.1998

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Applications of Geophysics to the Al Shaheen Field, Qatar, for Reservoir Characterisation and Field Development

Autor: T. Ting, Michael Emang, V. Zampetti, R. Lorenzen, L. Madsen, John Henderson, C. B. Raborn, A. Uldall, H. Cromie, C. Huegen

Publikováno v: IPTC 2014: International Petroleum Technology Conference.

Abstract A comprehensive seismic interpretation programme was recently initiated with the purpose of further increasing the use of 3D seismic data for reservoir characterisation and field development in the Al Shaheen Field, offshore Qatar. Reprocess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260d8d0a11371e5ea8dc249c894e7445
https://doi.org/10.3997/2214-4609-pdb.395.iptc-17664-ms

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An in vitro-differentiated human cell line as a model system to study the interaction of Neisseria gonorrhoeae with phagocytic cells

Autor: Joachim Saas, Dirk R. Lorenzen, Thomas F. Meyer, Christof R. Hauck

Publikováno v: Infection and Immunity. 65:1863-1869

The extreme host specificity of pathogenic neisseriae limits investigations aimed at the analysis of bacterial-host interactions almost completely to the use of in vitro models. Although permanent epithelial and endothelial cell lines are already ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf89f1fa057bd223d0233ae246b5db49
https://doi.org/10.1128/iai.65.5.1863-1869.1997

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Phenotypical and functional characterization of Fey receptor I (CD64)-negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity

Autor: Hans-Dieter Flad, Martin Ernst, Rudolf Fetting, Dirk R. Lorenzen, Evelin Grage-Griebenow

Publikováno v: European Journal of Immunology. 23:3126-3135

Fc gamma receptor I-positive (CD64+) and Fc gamma receptor I-negative (CD64-) monocytes were prepared from highly purified (elutriation-derived) human monocytes by cytofluorograph cell sorting, and a phenotypical and functional dissociation of the is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d527ceecbf2b40f33a65c6dc4b9285
https://doi.org/10.1002/eji.1830231213

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Stable cationic microparticles for enhanced model antigen delivery to dendritic cells

Autor: Julian Zimmermann, Ingo Siebenbrodt, Christian Wischke, Dirk R. Lorenzen, Hans-Hubert Borchert

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society. 114(3)

The objectives of this work were (i) to prepare physically stable cationic microparticles and (ii) to study the impact of the surface properties on microparticle phagocytosis and the phenotype of dendritic cells (DC). Protein loaded biodegradable mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1529bb3b172964dceb026032665e2a2b
https://pubmed.ncbi.nlm.nih.gov/16889866

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