Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R. Levent Büyükuysal"'
Autor:
Zulfiye Gul, R. Levent Büyükuysal
Publikováno v:
NeuroReport. 32:157-162
Objectives Glutamate excitotoxicity contributes to neurodegeneration during cerebral ischemia. Recent studies in the protective effect of glutamate against ischemia and hypoxia have shown the need for questioning the role of glutamate in energy metab
Publikováno v:
Experimental brain research. 238(11)
Although L-DOPA revolutionized in the treatment of Parkinson's disease, most patients developed motor complications after several years of treatment. Adjunctive therapy to L-DOPA with drugs related to dopaminergic signaling may reduce its dose withou
Publikováno v:
Neurological research. 42(3)
Objective: In vitro acute adult brain slice methods are instruments in developing our knowledge of the nervous system. Optimization of this method for obtaining high-quality brain slices is extreme...
Autor:
R. Levent Büyükuysal, Sami Aydin, Sinan Cavun, M. Sertac Yilmaz, William R. Millington, Nesrin Filiz Başaran
Publikováno v:
Neuropeptides. 58:23-29
Glycyl-L-glutamine (Gly-Gln; beta-endorphin(30-31)) is an endogenous dipeptide synthesized through the post-translational processing of beta-endorphin(1-31). Central Gly-Gln administration inhibits the rewarding properties of morphine and attenuates
Autor:
R. Levent Büyükuysal, Murat Gürsoy
Publikováno v:
Neurochemical Research. 33:1838-1844
Incubation of rat striatal slices in anoxic medium caused significant alterations in dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) outputs; while DA release increased several times, 50% decline in DOPAC output was observed under this condi
Publikováno v:
Neurochemical research. 39(7)
One hour incubation of rat cortical slices in a medium without oxygen and glucose (oxygen–glucose deprivation, OGD) increased S100B release to 6.53 ± 0.3 ng/ml/mg protein from its control value of 3.61 ± 0.2 ng/ml/mg protein. When these slices we
Mechanism of S100b release from rat cortical slices determined under basal and stimulated conditions
Autor:
R. Levent Büyükuysal, Murat Gürsoy
Incubation of rat cortical slices in a medium that was not containing oxygen and glucose (oxygen-glucose deprivation, OGD) caused a 200% increase in the release of S100B. However, when slices were transferred to a medium containing oxygen and glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ce01900c1cb0a4d16f97a9169abcce
http://hdl.handle.net/11452/25400
http://hdl.handle.net/11452/25400
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 381(5)
Glycyl-glutamine (Gly-Gln) is an endogenous dipeptide that is synthesized from beta-endorphin post-translationally. Previously, we showed that Gly-Gln prevents acquisition of morphine-conditioned place preference, a behavioral test of morphine reward
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