Zobrazeno 1 - 10
of 300
pro vyhledávání: '"R. Lesyk"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 95, Iss 1, Pp 31-43 (2023)
Cannabinoid ligands are known to possess neuroprotective actions and may have utility in the treatment of neurodegeneration. The major targets for cannabinoids include the classical CB1 cannabinoid receptor, as well as the novel cannabinoid receptor
Externí odkaz:
https://doaj.org/article/bdb3db9398744c3fb8c066fadd314083
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 6, Pp 93-100 (2021)
We assume that the violation of homocysteine (Hcy) metabolism and vitamin D level in mothers’ utero causes various abnormalities in offspring, including hard-woven teeth and periodontium impairments. The aim of this study was to evaluate the bioche
Externí odkaz:
https://doaj.org/article/2199a7c62d0c4d3cb50f2e4d849e0bbd
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 2, Pp 7-22 (2021)
Synthetic 4-thiazolidinone derivatives have a broad range of pharmacologic activities. Thus, 4-thiazolidinones are being investigated to create new molecules and develop active pharmaceutical substances for anticancer treatment. In our previous study
Externí odkaz:
https://doaj.org/article/13b7af7cfc354aaa90d609b3699f0a32
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 108-119 (2020)
A series of novel 2-(5-ylidene-4-oxo-2-thioxo-thiazolidin-3-yl)-succinimides and 5-ylidene-3-(1-arylpyrrolidine-2,5-dione)-thiazolidine-2,4-diones were synthesized. An efficient simple protocol for rhodanine-pyrrolidinedione hybrids synthesis which a
Externí odkaz:
https://doaj.org/article/40ca3598b9a341ab83a0562df3cf214b
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 2, Pp 7-17 (2019)
Oxidative stress is one of the main mechanisms by which anticancer chemotherapeutics damage normal tissues and organs. At the same time, it is an important biochemical mechanism of the neoplastic action of such medicines. The aim of the present study
Externí odkaz:
https://doaj.org/article/58e33db688cc444fb83359397767132f
Autor:
L. Kobylinska, I. Ivasechko, N. Skorokhyd, R. Panchuk, A. Riabtseva, N. Mitina, A. Zaichenko, R. Lesyk, B. Zimenkovsky, R. Stoika, S. G. Vari
Publikováno v:
Nanoscale Research Letters, Vol 14, Iss 1, Pp 1-16 (2019)
Abstract Aim To study whether water formulation of the complex of 4-thiazolidinone derivatives with a PEG-containing polymeric nanocarrier enhances their pro-apoptotic action towards rat glioma C6 cells. Methods Mechanisms of antineoplastic effects o
Externí odkaz:
https://doaj.org/article/4c8c9022051a407eac147877eceaa898
Publikováno v:
Праці Наукового товариства імені Шевченка. Медичні науки, Vol 49, Iss 1, Pp 26-26 (2017)
Small intestinal injury is one of the most commonly appeared pathologies resulting in use of medications such as: nonsteroidal anti-inflammatory drugs (NSAIDs), anti-tumor drugs and inhibitors of angiotensin-converting enzyme (ACE). Taking into consi
Externí odkaz:
https://doaj.org/article/5de988ef833b429096938f95de2c70e3
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 9, Pp o2721-o2722 (2012)
The title compound, C17H15Br2NO6S2·C2H5OH, is the esterification reaction product of 2-(8,10-dibromo-2,6-dioxo-3,5,5a,11b-tetrahydro-2H,6H-chromeno[4′,3′:4,5]thiopyrano[2,3-d]thiazol-5a-yl)acetic acid. Cleavage of the lactone ring and formation
Externí odkaz:
https://doaj.org/article/8606ba98438d4ba291acdc990ac4e2ec
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Akademický článek
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