Zobrazeno 1 - 10
of 918
pro vyhledávání: '"R. Lemoine"'
Autor:
Guozhong Jiang, Zhizhong Wang, Zhenguo Cheng, Weiwei Wang, Shuangshuang Lu, Zifang Zhang, Chinedu A. Anene, Faraz Khan, Yue Chen, Emma Bailey, Huisha Xu, Yunshu Dong, Peinan Chen, Zhongxian Zhang, Dongling Gao, Zhimin Wang, Jinxin Miao, Xia Xue, Pengju Wang, Lirong Zhang, Rathi Gangeswaran, Peng Liu, Louisa S. Chard Dunmall, Junkuo Li, Yongjun Guo, Jianzeng Dong, Nicholas R. Lemoine, Wencai Li, Jun Wang, Yaohe Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Esophageal squamous cell carcinoma (ESCC) is highly heterogeneous. Our understanding of full molecular and immune landscape of ESCC remains limited, hindering the development of personalised therapeutic strategies. To address this, we perfor
Externí odkaz:
https://doaj.org/article/c3c0976adb9a46179840a933958f546b
Autor:
R. Lemoine
Publikováno v:
Atmospheric Chemistry and Physics, Vol 4, Iss 4, Pp 1085-1096 (2004)
Ozone profiles from balloon soundings as well as SAGEII ozone profiles were used to detect anomalous large ozone concentrations of ozone in the lower stratosphere. These secondary ozone maxima are found to be the result of differential advection of o
Externí odkaz:
https://doaj.org/article/16aa3314e2b645a2b56419ac41d3df6b
Autor:
L. Martin, A. Granier, R. Lemoine, A. Dauba, S. Vermeersch, C. Aubert-Jacquin, C. Baron, Y. Lebranchu, C. Hoarau, F. Velge-Roussel
Publikováno v:
European Journal of Inflammation, Vol 12 (2014)
Probiotic bacteria have been shown to have health benefits in various situations (inflammation, allergy, infection). We previously showed that a bacteria-free fermentation product of Bifidobacterium breve C50 (BbC50sn) induced high IL-10 secretion by
Externí odkaz:
https://doaj.org/article/8a74fe30c7f9441782089cda8ab21373
Autor:
Wenping Zhou, Jinxin Miao, Zhenguo Cheng, Zhimin Wang, Jianyao Wang, Haoran Guo, Pengju Wang, Shuangshuang Lu, Lingling Si, Zhongxian Zhang, Louisa Chard Dunmall, Yanyan Liu, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 216-226 (2023)
CD19-targeted chimeric antigen receptor-modified T (CD19 CAR-T) cell therapy has been demonstrated as one of the most promising therapeutic strategies for treating B cell malignancies. However, it has shown limited treatment efficacy for diffuse larg
Externí odkaz:
https://doaj.org/article/9d62516814ab4d5fb98012e3b88a0c17
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Oncolytic virotherapy (OVT) is a promising form of cancer treatment that uses genetically engineered viruses to replicate within cancer cells and trigger anti-tumor immune response. In addition to killing cancer cells, oncolytic viruses can also remo
Externí odkaz:
https://doaj.org/article/485dd795262446aba8eb2eff8742f881
Autor:
Wenyi Yan, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang, Yafeng Wang, Pengju Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
γδ T cells, a specialized subset of T lymphocytes, have garnered significant attention within the realm of cancer immunotherapy. Operating at the nexus between adaptive and innate immunological paradigms, these cells showcase a profound tumor disce
Externí odkaz:
https://doaj.org/article/e0911c4bb9db48e9ad80c49c2fe0fdb4
Autor:
Yangyang Jia, Yanru Wang, Louisa S Chard Dunmall, Nicholas R. Lemoine, Pengju Wang, Yaohe Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancer immunotherapy (CIT) has emerged as an exciting new pillar of cancer treatment. Although benefits have been achieved in individual patients, the overall response rate is still not satisfactory. To address this, an ideal preclinical animal model
Externí odkaz:
https://doaj.org/article/41c87dac90124c76b9c6c211a853f0dd
Autor:
Renato B. Baleeiro, Christian J. Bouwens, Peng Liu, Carmela Di Gioia, Louisa S. Chard Dunmall, Ai Nagano, Rathistevy Gangeswaran, Claude Chelala, Hemant M. Kocher, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
MHC class II expression is a hallmark of professional antigen-presenting cells and key to the induction of CD4+ T helper cells. We found that these molecules are ectopically expressed on tumor cells in a large proportion of patients with pancreatic d
Externí odkaz:
https://doaj.org/article/aa1693edb0764d5493563bed35308e13
Autor:
Renato B. Baleeiro, Louisa S. Chard Dunmall, Peng Liu, Shuangshuang Lu, Yuchun Lone, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
RAS mutations occur in approximately 20% of all cancers and given their clonality, key role as driver mutation, association with poor prognosis and undruggability, they represent attractive targets for immunotherapy. We have identified immunogenic pe
Externí odkaz:
https://doaj.org/article/07bffd94031348cb88fac1cc6d222fd5
Autor:
Daniel E Foxler, Katherine S Bridge, John G Foster, Paul Grevitt, Sean Curry, Kunal M Shah, Kathryn M Davidson, Ai Nagano, Emanuela Gadaleta, Hefin I Rhys, Paul T Kennedy, Miguel A Hermida, Ting‐Yu Chang, Peter E Shaw, Louise E Reynolds, Tristan R McKay, Hsei‐Wei Wang, Paulo S Ribeiro, Michael J Plevin, Dimitris Lagos, Nicholas R Lemoine, Prabhakar Rajan, Trevor A Graham, Claude Chelala, Kairbaan M Hodivala‐Dilke, Ian Spendlove, Tyson V Sharp
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-18 (2018)
Abstract The adaptive cellular response to low oxygen tensions is mediated by the hypoxia‐inducible factors (HIFs), a family of heterodimeric transcription factors composed of HIF‐α and HIF‐β subunits. Prolonged HIF expression is a key contri
Externí odkaz:
https://doaj.org/article/9b04680e29334b599d9575042b42aeeb