Zobrazeno 1 - 10
of 3 455
pro vyhledávání: '"R. Lemoine"'
Autor:
Guozhong Jiang, Zhizhong Wang, Zhenguo Cheng, Weiwei Wang, Shuangshuang Lu, Zifang Zhang, Chinedu A. Anene, Faraz Khan, Yue Chen, Emma Bailey, Huisha Xu, Yunshu Dong, Peinan Chen, Zhongxian Zhang, Dongling Gao, Zhimin Wang, Jinxin Miao, Xia Xue, Pengju Wang, Lirong Zhang, Rathi Gangeswaran, Peng Liu, Louisa S. Chard Dunmall, Junkuo Li, Yongjun Guo, Jianzeng Dong, Nicholas R. Lemoine, Wencai Li, Jun Wang, Yaohe Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Esophageal squamous cell carcinoma (ESCC) is highly heterogeneous. Our understanding of full molecular and immune landscape of ESCC remains limited, hindering the development of personalised therapeutic strategies. To address this, we perfor
Externí odkaz:
https://doaj.org/article/c3c0976adb9a46179840a933958f546b
Autor:
Wenping Zhou, Jinxin Miao, Zhenguo Cheng, Zhimin Wang, Jianyao Wang, Haoran Guo, Pengju Wang, Shuangshuang Lu, Lingling Si, Zhongxian Zhang, Louisa Chard Dunmall, Yanyan Liu, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 216-226 (2023)
CD19-targeted chimeric antigen receptor-modified T (CD19 CAR-T) cell therapy has been demonstrated as one of the most promising therapeutic strategies for treating B cell malignancies. However, it has shown limited treatment efficacy for diffuse larg
Externí odkaz:
https://doaj.org/article/9d62516814ab4d5fb98012e3b88a0c17
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Oncolytic virotherapy (OVT) is a promising form of cancer treatment that uses genetically engineered viruses to replicate within cancer cells and trigger anti-tumor immune response. In addition to killing cancer cells, oncolytic viruses can also remo
Externí odkaz:
https://doaj.org/article/485dd795262446aba8eb2eff8742f881
Autor:
Weatherall, David
Publikováno v:
BMJ: British Medical Journal, 1997 Apr 01. 314(7086), 1057-1057.
Externí odkaz:
https://www.jstor.org/stable/25174229
Autor:
Wenyi Yan, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang, Yafeng Wang, Pengju Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
γδ T cells, a specialized subset of T lymphocytes, have garnered significant attention within the realm of cancer immunotherapy. Operating at the nexus between adaptive and innate immunological paradigms, these cells showcase a profound tumor disce
Externí odkaz:
https://doaj.org/article/e0911c4bb9db48e9ad80c49c2fe0fdb4
Autor:
Yijie Sun, Zhe Zhang, Chenglin Zhang, Na Zhang, Pengju Wang, Yongchao Chu, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 105-119 (2022)
Glioblastoma (GBM) is the most common primary malignant tumor in the brain, accounting for 51.4% of all primary brain tumors. GBM has a highly immunosuppressive tumor microenvironment (TME) and, as such, responses to immunotherapeutic strategies are
Externí odkaz:
https://doaj.org/article/8f09c6d055de4f21a20473329d2488c7
Autor:
Dujuan Cao, Qianqian Song, Junqi Li, Louisa S. Chard Dunmall, Yuanyuan Jiang, Bin Qin, Jianyao Wang, Haoran Guo, Zhenguo Cheng, Zhimin Wang, Nicholas R. Lemoine, Shuangshuang Lu, Yaohe Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 25, Iss , Pp 264-275 (2022)
Immunotherapies, such as immune checkpoint inhibitors (ICIs) and chimeric antigen receptor-T (CAR-T) cells, are only efficient in a small proportion of tumor patients. One of the major reasons for this is the lack of immune cell infiltration and acti
Externí odkaz:
https://doaj.org/article/6aa4fe715b2b437d9107fedce2733a9f
Autor:
Yangyang Jia, Yanru Wang, Louisa S Chard Dunmall, Nicholas R. Lemoine, Pengju Wang, Yaohe Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancer immunotherapy (CIT) has emerged as an exciting new pillar of cancer treatment. Although benefits have been achieved in individual patients, the overall response rate is still not satisfactory. To address this, an ideal preclinical animal model
Externí odkaz:
https://doaj.org/article/41c87dac90124c76b9c6c211a853f0dd
Autor:
Renato B. Baleeiro, Christian J. Bouwens, Peng Liu, Carmela Di Gioia, Louisa S. Chard Dunmall, Ai Nagano, Rathistevy Gangeswaran, Claude Chelala, Hemant M. Kocher, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
MHC class II expression is a hallmark of professional antigen-presenting cells and key to the induction of CD4+ T helper cells. We found that these molecules are ectopically expressed on tumor cells in a large proportion of patients with pancreatic d
Externí odkaz:
https://doaj.org/article/aa1693edb0764d5493563bed35308e13
Autor:
M. G. Dunlop
Publikováno v:
Genetical Research. 69:159-162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfdd2215116d70a595d2fefdd17bcdc
https://doi.org/10.1017/s0016672397239327
https://doi.org/10.1017/s0016672397239327