Zobrazeno 1 - 10
of 58
pro vyhledávání: '"R. Lemmer"'
Autor:
Jonathan Almer, S. R. Lemmer, Jinesh Dahal, Aaron P. Stebner, G. M. Hommer, Jun-Sang Park, Bjørn Clausen, J. Vignes, Donald W. Brown, Peter Kenesei, A. Mashayekhi, Z. D. Brunson
Publikováno v:
Experimental Mechanics. 59:749-774
An experimental platform for multiscale studies of materials subjected to plane stress loads is presented. Coupling with far-field high-energy diffraction microscopy for grain-by-grain measurements of elastic strains and rotations provides an additio
Autor:
H. R. Lemmer
Publikováno v:
HTS Teologiese Studies/Theological Studies, Vol 46, Iss 1/2, Pp 102-119 (1990)
Although an almost forgotten debate, the issue of eschatology in Ephesians remains unresolved and possibly insoluble. However, presuppositions inevitably determine the final outcome of investigations. This latter datum is characterized, indicating th
Externí odkaz:
https://doaj.org/article/e52024a5c3134768bca84c8e7f19d8ec
Autor:
Wilma J. Breytenbach, Marique Aucamp, Chrisna Gouws, Trizel du Toit, Hendrik J. R. Lemmer, Maides M. Malan, Josias H. Hamman
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 41:575-586
Currently, macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract. This study investigated binary combinations of chemi
Publikováno v:
Die Pharmazie. 71(6)
Molecular weight and log P remain the most frequently used physicochemical properties in models that predict skin permeability. However, several reports over the past two decades have suggested that predictions made by these models may not be suffici
Publikováno v:
Digestive Diseases and Sciences. 52:2463-2471
Drug-induced liver injury (DILI) is a term that describes abnormalities in liver function tests (LFTs) related to medication intake. DILI, a subtype of hepatotoxicity, does not include hepatic injuries related to nonmedicinal compounds, including her
Publikováno v:
Seminars in Liver Disease. 26:373-384
Gene expression profile analysis through DNA microarrays and other high-throughput technologies permit simultaneous investigation of all genes within a biologic sample, providing a snapshot of the transcriptional state of healthy or diseased tissue.
Autor:
Jonas Larsson, Shoshiro Oe, Elizabeth A. Conner, Snorri S. Thorgeirsson, Eric R. Lemmer, Valentina M. Factor, Per Levéen, Stefan Karlsson
Publikováno v:
Hepatology. 40:1098-1105
Transforming growth factor beta (TGF-beta) is a potent inhibitor of hepatocyte proliferation in vitro and is suggested to be a key negative regulator of liver growth. To directly address the role of TGF-beta signaling in liver regeneration in vivo, t
Publikováno v:
Journal of Chromatographic Science. 41:57-62
A rapid liquid chromatographic method is validated for the quantitative analysis of phentolamine. Phentolamine exists in three forms for this investigation: as a mesylate salt, hydrochloride salt, and free base. In solution, phentolamine dissociates
Autor:
Masako Omori, Eric R Lemmer, Valentina M. Factor, Snorri S. Thorgeirsson, Elizabeth A. Conner, Peter J. Wirth
Publikováno v:
Oncogene. 19:5054-5062
Deregulation of E2F transcriptional control has been implicated in oncogenic transformation. Consistent with this idea, we recently demonstrated that during hepatocarcinogenesis in c-myc/TGFalpha double transgenic mice, there is increased expression
Autor:
Eric R. Lemmer, Walter F. O. Marasas, Enid G. Shephard, J. Peter Cruse, Ralph E. Kirsch, Stefan Abel, Wentzel C. A. Gelderblom, Beverley L Seymour, Pauline de la M. Hall
Publikováno v:
Cancer Letters. 146:207-215
The present study was performed to determine whether excess hepatic iron modulates the cancer-initiating and promoting properties of FB1. Thirty-eight male F344 rats were divided into four dietary treatment groups: (i) control diet (AIN, n = 8); (ii)