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Publikováno v:
Theoretical and Applied Fracture Mechanics. 101:141-151
Steady-state crack propagation is the advance of a self-similar crack tip with a constant driving force. Though steady-state growth is often described with analytical models, it is rarely experimentally observed or characterized under quasi-static lo
Publikováno v:
Fatigue & Fracture of Engineering Materials & Structures. 40:1809-1824
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purp
Autor:
Benjamin D. Horning, Sandip Chatterjee, Bruno E. Correia, Arthur J. Olson, Gonzalo E. González-Páez, Bryan R. Lanning, Dennis W. Wolan, John R. Teijaro, Stefano Forli, Benjamin F. Cravatt, Kenneth M. Lum, Keriann M. Backus
Publikováno v:
Nature
Small molecules are powerful tools for investigating protein function and can serve as leads for new therapeutics. Most human proteins, however, lack small-molecule ligands, and entire protein classes are considered “undruggable” 1,2. Fragment-ba
Autor:
James G. Collins, E. C. Strauch, Gregory P. Dillon, Wade R. Lanning, Christopher L. Muhlstein
Publikováno v:
Fatigue & Fracture of Engineering Materials & Structures. 39:1124-1137
In this work we present a strain field mining methodology where the intensities and spatial distributions of strains in double lap strap epoxy (EA 9394) bonded joints are measured, analysed and correlated with bond strength. While the global behaviou
Autor:
Irina Novikova, Nikunjkumar Prajapati, Nathan Super, Nicholas R. Lanning, Jonathan P. Dowling
We investigate the spatial and quantum intensity correlations between the probe and Stokes optical fields produced via four-wave mixing in a double-{\Lambda} configuration, when both incoming probe and control fields carry non-zero optical orbital an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b732a1425043107c59a80f4e2fad8cc
Autor:
W. L. Maranville, David A. Smith, Christopher J. Stolz, Tayyab I. Suratwala, D. R. Bopp, T. Silva, P. E. Miller, Joseph A. Menapace, J. Stanley, Paul J. Wegner, K. Kasl, Davorin Peceli, J D Nissen, D. Mason, J. M. Di Nicola, T. Spinka, Jakub Novák, Shawn Betts, A. Naylon, S. Telford, J. Horner, Emily Sistrunk, Doseok Kim, R. Lanning, Paul Rosso, R. Demaret, K. Charron, R. Steele, Bedřich Rus, J. Jarboe, C. Gates, Josef Cupal, Andy J. Bayramian, Christopher D. Marshall, L. Koubíková, Alvin C. Erlandson, Kathleen I. Schaffers, Robert J. Deri, Constantin Haefner, Jakub Horáček, Salmaan H. Baxamusa, S. Buck, Petr Mazurek, J. Lusk, J. Weiss, D. VanBlarcom, J. P. Armstrong, J. Thoma, E. S. Fulkerson, E. Koh
Publikováno v:
Scopus-Elsevier
We have demonstrated the world's highest average power, fully diode-pumped, petawatt-class peak power laser, the High-repetition-rate Advanced Petawatt Laser System (HAPLS) [1-3]. These first commissioning results at 16J (stretched) at 3%Hz fully val
Autor:
R. Steele, E. Koh, J. Horner, A. Naylon, Doseok Kim, K. Charron, P. E. Miller, David A. Smith, Davorin Peceli, Paul Rosso, T. Spinka, Shawn Betts, Paul J. Wegner, J. Jarboe, S. Buck, Christopher D. Marshall, L. Koubíková, Kathleen I. Schaffers, R. Bopp, E. S. Fulkerson, Constantin Haefner, K. Kasl, Jakub Horáček, Jakub Novák, J. Weiss, D. Mason, M. A. Drouin, J. Thoma, R. Lanning, Petr Mazurek, Bedřich Rus, Emily Sistrunk, W. Maranville, D. VanBlarcom, S. Telford, Robert J. Deri, Joseph A. Menapace, Andy J. Bayramian, Alvin C. Erlandson, J. Stanley, Josef Cupal
Publikováno v:
Conference on Lasers and Electro-Optics.
The HAPLS laser system has been commissioned to its first integrated performance milestone, delivering laser pulses with 16J sub-30fs duration at a 3⅓Hz repetition rate. This first all-diode-pumped petawatt-class laser offers the average powers req
Autor:
John Charles Kath, Theodore O. Johnson, Landon R. Whitby, Benjamin F. Cravatt, Baoxian Wei, Chu Wang, Mark E. Schnute, Melissa M. Dix, Lee R. Roberts, Laurence O. Whiteley, Adam M. Gilbert, Jonathan J. Hulce, Sherry Niessen, Erik C. Hett, Chris Joslyn, Matthew Merrill Hayward, Bryan R. Lanning, John Douhan
Publikováno v:
Nature chemical biology
Kinases are principal components of signal transduction pathways and the focus of intense basic and drug discovery research. Irreversible inhibitors that covalently modify non-catalytic cysteines in kinase active-sites have emerged as valuable probes
Publikováno v:
Engineering Fracture Mechanics. 218:106540
Cracks grow in millimeter-scale, ductile metal sheets when a transverse neck fracture process zone fails by microvoid coalescence. Here we showed that the crack growth mechanism changed to a different steady-state process when sheet thicknesses were