Zobrazeno 1 - 10
of 17
pro vyhledávání: '"R. L. Shone"'
Autor:
B.S. Tsai, Stuart Levin, S. W. Djuric, J. M. Zemaitis, D. L. Widomski, Timothy S. Gaginella, R. E. Walsh, D. J. Fretland, R. L. Shone
Publikováno v:
Inflammation. 14:727-739
Neutrophil (PMNL) infiltration is a prominent feature of human psoriasis. Psoriatic skin lesions contain abnormally high amounts of leukotriene B4 (LTB4), itself a potent PMNL chemoattractant both in vivo and in vitro. SC-41930 (7-[3-(4-acetyl-3-meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126c942ddb80468af6a4899e688b971c
https://doi.org/10.1007/bf00916375
https://doi.org/10.1007/bf00916375
Publikováno v:
Agents and Actions. 34:172-174
The accepted model for the human demyelinating disease, multiple sclerosis (MS), is experimental allergic encephalomyelitis (EAE). We assessed the ability of SC-41930(7-[3(4-acetyl-3-methoxy-2-propyl-phenoxy)-propoxy]- 3,4-dihydro-8-propyl-2H-1-benzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fa85232b1e6c1f2dc4b8a766f687bb
https://doi.org/10.1007/bf01993269
https://doi.org/10.1007/bf01993269
Autor:
D J, Fretland, D, Widomski, B S, Tsai, J M, Zemaitis, S, Levin, S W, Djuric, R L, Shone, T S, Gaginella
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 255(2)
Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract that includes ulcerative colitis and Crohn's disease. Leukotriene B4 is thought to be a prominent proinflammatory mediator in these diseases, in that leukotri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4532a71a31995d3b9b64d46092597c87
https://pubmed.ncbi.nlm.nih.gov/2173749
https://pubmed.ncbi.nlm.nih.gov/2173749
Publikováno v:
Inflammation. 13:601-605
Leukotriene B4 (LTB4) is a proinflammatory product of arachidonic acid metabolism that has been implicated as a mediator in a number of inflammatory diseases. When injected intradermally into the cavine. LTB4 elicits a dose-dependent immigration (che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb9d777b60148b587030b0563259132
https://doi.org/10.1007/bf00916766
https://doi.org/10.1007/bf00916766
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 38:169-172
Psoriasis is a disease state characterized by epidermal proliferation, neutrophil infiltration, along with release of the proinflammatory mediators leukotriene-B 4 (LTB 4 ) and 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE]. LTB 4 and 12(R)-HETE are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29580c63461bed8fc0e806c265fd952
https://doi.org/10.1016/0952-3278(89)90067-7
https://doi.org/10.1016/0952-3278(89)90067-7
Publikováno v:
Tetrahedron Letters. 12:219-222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8c07275800c87cb3ea68bda3274fcf
https://doi.org/10.1016/s0040-4039(01)96402-0
https://doi.org/10.1016/s0040-4039(01)96402-0
Autor:
S. W. Djuric, D. L. Widomski, J. M. Zemaitis, B.S. Tsai, Stuart Levin, R. L. Shone, D. J. Fretland, R.F. Bauer
Publikováno v:
Agents and Actions. 27:395-397
SC-41930, 7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)-propoxy]-3,4-dihydro-8-p ropyl- 2H-1-benzopyran-2-carboxylic acid, is a potent in vitro leukotriene-B4 (LTB4) receptor antagonist. LTB4 levels are elevated in colonic tissue of inflammatory bowel di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6518d06f5c187219fe5d0ca68fea6237
https://doi.org/10.1007/bf01972832
https://doi.org/10.1007/bf01972832
Autor:
R. L. SHONE
Publikováno v:
Chemischer Informationsdienst. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3cd0728325fed69ea9012da77c541ee
https://doi.org/10.1002/chin.197939172
https://doi.org/10.1002/chin.197939172
Autor:
D Villani-Price, B.S. Tsai, J. M. Zemaitis, Butchko Gm, D. J. Fretland, P. W. Collins, R. L. Shone, Jones Ph, S. W. Djuric, R H Keith
Publikováno v:
Journal of medicinal chemistry. 32(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fdf20deac5fe1376a403c449fd65d3
https://pubmed.ncbi.nlm.nih.gov/2542550
https://pubmed.ncbi.nlm.nih.gov/2542550
Autor:
R. L. SHONE
Publikováno v:
Chemischer Informationsdienst. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893ad543f69671299bf40383f521fb56
https://doi.org/10.1002/chin.197805336
https://doi.org/10.1002/chin.197805336