Zobrazeno 1 - 10 of 11 pro vyhledávání: '"R. L. Saylors"'
1
Phase I study of topotecan in combination with cyclophosphamide in pediatric patients with malignant solid tumors: a Pediatric Oncology Group Study
Autor: B Bell, C F Stewart, W C Zamboni, R L Saylors rd, Kimo C. Stine, T J Vietti, D A Wall
Publikováno v: Journal of Clinical Oncology. 16:945-952
PURPOSE To determine the maximum-tolerated dose (MTD) and dose-limiting toxicity of topotecan when combined with cyclophosphamide in pediatric patients with recurrent or refractory malignant solid tumors. PATIENTS AND METHODS A total of 33 patients r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5656ee3ed9a306d57b91e84db32e3ad
https://doi.org/10.1200/jco.1998.16.3.945
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3
Secondary acute myelogenous leukemia following safe exposure to etoposide
Autor: Kimo C. Stine, David L. Becton, R L Saylors, J R Sawyer
Publikováno v: Journal of Clinical Oncology. 15:1583-1586
PURPOSE To present two patients as illustrations of the risk of developing secondary acute myelogenous leukemia (sAML) when theoretically safe doses of etoposide (VP-16) are used. PATIENTS AND METHODS Patient no. 1 was a 15-year-old white girl diagno
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bf1748fd6de04499b49a03430e859f9
https://doi.org/10.1200/jco.1997.15.4.1583
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4
Liver-directed gene therapy: quantitative evaluationof promoter elements by using in vivo retroviral transduction
Autor: S. C. Kennedy, S. D. Rettinger, Xiaoyun Wu, Katherine P. Ponder, R. L. Saylors, M. W. Flye, D. G. Hafenrichter
Publikováno v: Proceedings of the National Academy of Sciences. 91:1460-1464
Liver-directed gene therapy will be applicable to many inherited diseases. Although various protocols have been devised for in vivo delivery of retrovirus, comparison of hepatocyte transduction frequencies has been difficult due to variations in retr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2e50191fddd43616ed22788f326963
https://doi.org/10.1073/pnas.91.4.1460
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5
Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group phase II study
Autor: Kimo C. Stine, Robert J. Hayashi, James L. Kepner, Teresa J. Vietti, R L Saylors rd, James P. Sullivan, Michael E. Harris, Mark L. Bernstein, Donna A. Wall
Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 19(15)
PURPOSE: To determine the response rate of the combination of cyclophosphamide and topotecan in pediatric patients with recurrent or refractory malignant solid tumors. PATIENTS AND METHODS: A total of 91 pediatric patients, 83 of whom were fully asse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdeb7d2b3fe917086087f520f8bab26
https://pubmed.ncbi.nlm.nih.gov/11481351
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7
2-Chlorodeoxyadenosine (2-CDA) for the treatment of refractory or recurrent Langerhans cell histiocytosis (LCH) in pediatric patients
Autor: K C, Stine, R L, Saylors, L L, Williams, D L, Becton
Publikováno v: Medical and pediatric oncology. 29(4)
Pediatric patients with Langerhans cell histiocytosis (LCH) may become refractory to conventional therapy or present with repeated recurrences over several years. Current therapeutic options such as prednisone, vinblastine, etoposide, and cyclosporin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b15747bdc4884973b6286e5f8339a5f
https://pubmed.ncbi.nlm.nih.gov/9251735
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8
Prenatal detection of neuroblastoma by fetal ultrasonography
Autor: R L, Saylors, S L, Cohn, E R, Morgan, G M, Brodeur
Publikováno v: The American journal of pediatric hematology/oncology. 16(4)
We report three cases of neuroblastoma diagnosed by prenatal ultrasound examination and examine the biologic features of tumors diagnosed prenatally.Neuroblastoma is the most common tumor detected in the newborn period. Thus, some of these tumors dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0caa25215f3f293f68d8e0f240103dc
https://pubmed.ncbi.nlm.nih.gov/7978056
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9
Infrequent p53 gene mutations in medulloblastomas
Autor: R L, Saylors, D, Sidransky, H S, Friedman, S H, Bigner, D D, Bigner, B, Vogelstein, G M, Brodeur
Publikováno v: Cancer research. 51(17)
Cytogenetic and molecular studies of medulloblastomas have demonstrated frequent loss of sequences from the short arm of chromosome 17, possibly implicating loss or inactivation of the p53 tumor suppressor gene. We amplified exons 5 through 8 of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f36ae6a965d48648942f81c3e9cbf44c
https://pubmed.ncbi.nlm.nih.gov/1873817
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10
Neuroblastoma, retinoblastoma, and brain tumors in children
Autor: Garrett M. Brodeur, R L Saylors rd
Publikováno v: Current opinion in oncology. 3(3)
Considerable progress has been made recently in the biologic understanding and the clinical management of pediatric tumors of the peripheral and central nervous system. Here we review important representative studies published primarily in the past 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a7c155dd9f03a974389c8c0f5ee3ac
https://pubmed.ncbi.nlm.nih.gov/1892917
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