Zobrazeno 1 - 10
of 46
pro vyhledávání: '"R. L. Polak"'
Publikováno v:
The Journal of Physiology. 309:199-214
1. Frog sartorius muscles were treated with an irreversible cholinesterase inhibitor and then incubated in Ringer with 2 mM-LaCl3. The amounts of ACh in the tissue and medium were assayed by mass fragmentography, miniature end-plate potentials (min.
Publikováno v:
Journal of Physiology, 349, 663-686
Enzymatic hydrolysis of acetylcholine (ACh) was determined in intact frog sartorius muscles or their homogenates. The Vmax was 29 nmol min-1 in intact muscles and 46 nmol min-1 per muscle in homogenates, and the Km was 6 and 0.2 mM, respectively. The
Publikováno v:
Proceedings of the Royal Society of London. Series B. Biological Sciences. 197:285-297
Extracts of frog sartorius muscles were assayed for their acetylcholine (ACh) content by means of pyrolysis-gas chromatography/mass spectrometry. Freshly dissected whole muscles contained 43 ± 3.1 (22) pmol ACh, and apart from ACh, no other related
Publikováno v:
Acta Physiologica Scandinavica. 115:201-207
In experiments on the isolated extensor digitorum longus muscle of the rat it was shown that 4-aminoquinoline (125-250 micro M) altered the amplitude distribution of spontaneous miniature endplate potentials to include a large portion of giant miniat
Autor:
J. J. Beckorinqh, C. Korstanje, P. A. van Zwieten, H. W. G. M. Boddeke, F. A. M. Jonkman, M. Daemen, H. van Essen, J. Smits, H. Thljssen, E. A. de Bruijn, O. Driessen, J. Hermans, P. A. de Graeff, J. H. Kingma, W. H. van Gilst, K. Bel, C. D. J. de Langen, H. Wesselinq, H. N. Doods, D. Davidesko, M. -J. Mathy, H. D. Batink, A. de Jonge, B. Ellenbroek, T. Klockgether, L. Turskit, M. Schwarz, A. Cools, N. A. P. Franken, J. L. van Delft, A. van Langevelde, T. M. A. R. Dubbelman, J. A. Oosterhuis, W. M. Star, J. P. A. Marljnissen, J. G. Journée-de Korver, E. K. J. Pauwels, G. R. M. M. Haenen, A. Bast, J. de Vries, N. P. E. Vcrmeulen, H. Timmerman, J. G. Hugtenburg, J. J. Beckeringh, B. J. A. Janssen, H. A. J. Struyker-Boudier, J. F. N. Smits, P. A. M. Jonkman, P. W. Man, J. T. A. Knape, C. B. Lambalk, H. van Kessel, G. P. van Rees, J. Schoemaker, J. H. C. M. Lammers, W. Meelis, M. R. Kruk, A. M. van der Poel, F. J. P. Lippens, C. F. M. van Valkenburg, J. A. van der Krogt, E. W. C. Krick, R. D. M. Belfroid, E. L. Noach, C. Loesberg, F. M. A. Woutersen-v. Nijnanten, F. P. Nijkamp, P. C. Molenaar, B. S. Pen, R. L. Polak, H. N. M. W. Nievelstein, C. M. Tijssen, J. F. M. Smits, J. F. Plant jé, J. C. Stoof, Kaghoebar Maikel, A. Jan, M. Huisman, Cees A. M. van Ginneken, F. D. Rahusen, G. T. Robillard, Ch. R. N. Wildevuur, F. C. M. Russel, P. E. M. van der Linden, W. G. Vermeulen, C. A. M. van Ginneken, R. P. J. H. Smits, H. U. M. Steinhusch, A. H. Mulder, E. M. J. ten Brink, J. van der Plas, P. L. M. van Giersbergen, V. M. Wlegant, W. de Jong, C. J. van Koppen, M. W. Hermanussen, C. N. Verrijp, J. F. Rodrigues de Miranda, A. J. Beld, J. W. J. Lammers, A. J. M. van Oosterhout, Arnold G. Vulto, Trevor Sharp, Urban Ungerstedt, G. Wolterink, J. M. van Ree
Publikováno v:
Pharmaceutisch Weekblad. 7:228-236
Publikováno v:
The Journal of Physiology. 334:245-254
1. Mass fragmentography was used to measure the tissue content and release of acetylcholine (ACh) by frog sartorius muscles, which had been previously treated with an irreversible cholinesterase inhibitor. The frequency of miniature end-plate current
Autor:
G. T. H. Van Kempen, B S Oen, B Ceccarelli, F Torri-Tarelli, Peter C. M. Molenaar, R. L. Polak
Publikováno v:
The Journal of Physiology. 408:233-249
1. Frog sartorius muscles were treated with an irreversible cholinesterase inhibitor and then incubated in isotonic potassium propionate solution (isotonic KPr). Total and bound, presumably vesicular, acetylcholine (ACh) in the tissue and ACh in the
Publikováno v:
The Journal of Physiology. 181:308-316
Autor:
R. L. Polak, Peter C. M. Molenaar
Publikováno v:
British Journal of Pharmacology. 40:406-417
1. Cortical slices from rat brain were incubated in media containing the irreversible cholinesterase inhibitor soman and a high KCl concentration, and the release and synthesis of acetylcholine (ACh) were determined.2. Atropine enhanced the release a