Výsledky vyhledávání - "R. L. Joiner"

The Effect on Sperm Production in Adult Sprague-Dawley Rats Exposed by Gavage to Bisphenol A between Postnatal Days 91-97

Autor: John Ashby, Joseph K. Haseman, R. L. Joiner, P. A. Lefevre, Helen Tinwell

Publikováno v: Toxicological Sciences. 74:129-138

M. Sakaue et al. (2001,J. Occup. Health vol. 43, pp. 185-190) have described how oral exposure of sexually mature male rats to bisphenol A (BPA) between postnatal days (PND) 91-97 led to a reduction in daily sperm production (DSP) 5 weeks later (18 w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534e3220d4bda0314f637d96e90f31b9
https://doi.org/10.1093/toxsci/kfg093

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In Vitro Percutaneous Absorption of Nonylphenol (NP) and Nonylphenol Ethoxylates (NPE-4 and NPE-9) in Isolated Perfused Skin

Autor: James D. Brooks, Nancy A. Monteiro-Riviere, Jim E. Riviere, Glenn S. Simon, John P. Van Miller, R. L. Joiner

Publikováno v: Journal of Toxicology: Cutaneous and Ocular Toxicology. 22:1-11

Skin contact with nonylphenol ethoxylates (NPE), a group of widely used surfactants, is the primary source of human exposure. Previous studies have shown that the absorption of NPE through human and animal skin in vitro is limited (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8e98add3c354c6883d598b27db2ee04
https://doi.org/10.1081/cus-120019325

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Comparison of the Developmental and Reproductive Toxicity of Diethylstilbestrol Administered to Rats in Utero, Lactationally, Preweaning, or Postweaning

Autor: J. P. Van Miller, N. Wallis, Helen Tinwell, P. A. Lefevre, R. L. Joiner, John Ashby, J. Odum, Robert E. Chapin

Publikováno v: Toxicological Sciences. 68:147-163

The objective of the study was to determine which period of exposure produces the most marked effects on the reproductive capacity and sexual development of the rat, with particular emphasis on the relative sensitivity of in utero and postnatal expos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135ab69e25ffea951786b51c896b2175
https://doi.org/10.1093/toxsci/68.1.147

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Uterotrophic Activity of Bisphenol A in the Immature Mouse

Autor: R. L. Joiner, Helen Tinwell, John Ashby, Jeff Foster, Ian Pate, A. Soames

Publikováno v: Regulatory Toxicology and Pharmacology. 32:118-126

Bisphenol A (BPA) has been evaluated in eight independent immature mouse uterotrophic assays using the subcutaneous route of administration, and in a single study employing oral gavage. The dose range covered was from 0.02 μg to 300 mg/kg BPA and so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742b085351dfe4114d97ac6be1f21ec2
https://doi.org/10.1006/rtph.2000.1412

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Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin

Autor: James D. Brooks, John P. Van Miller, Glenn S. Simon, R. L. Joiner, Nancy A. Monteiro-Riviere, Jim E. Riviere

Publikováno v: Toxicology and Industrial Health. 16:49-57

The purpose of this study was to assess the percutaneous absorption of nonylphenol (NP) and the nonylphenol ethoxylates, NPE-4 and NPE-9, in human, porcine and rat skin. In vitro studies with the NPEs were conducted for 8 h in flowthrough diffusion c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be629ce9c60fee43213263020ef0a12a
https://doi.org/10.1177/074823370001600201

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Normal Reproductive Organ Development in Wistar Rats Exposed to Bisphenol A in the Drinking Water

Autor: John H. Butala, Stuart Cagen, R. L. Joiner, Gauke Veenstra, R.N. Shiotsuka, Stephen S. Dimond, John M. Waechter, L.R. Harris, F.W. Jekat, W.J. Breslin

Publikováno v: Regulatory Toxicology and Pharmacology. 30:130-139

Bisphenol A (BPA) is a chemical used primarily as a monomer in the manufacture of numerous chemical products, such as epoxy resins and polycarbonate. The objective of this study was to evaluate potential effects of BPA on sexual development of male r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde9c83807622ded9bc50000d50c5386
https://doi.org/10.1006/rtph.1999.1340

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Effects ofp-nonylphenol (np) and diethylstilboestrol (des) on the alderley park (alpk) rat: comparison of mammary gland and uterus sensitivity following oral gavage or implanted mini-pumps

Autor: R. L. Joiner, John Ashby, Jeff Foster, Anthony R. Soames, J. Odum, J. P. Van Miller, I. T. G. Pyrah

Publikováno v: Journal of Applied Toxicology. 19:367-378

An earlier report by Colerangle and Roy indicated that administration of p-nonylphenol (NP) to Noble rats, via subcutaneously implanted mini-pumps at estimated doses of 53.2 and 0.073 mg kg(-1) day(-1) for 11 days, led to proliferation of the mammary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75e0a44f0ef441ed50bf0e72988bb969
https://doi.org/10.1002/(sici)1099-1263(199909/10)19:5<367::aid-jat593>3.0.co

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Comparative Activities ofp-Nonylphenol and Diethylstilbestrol in Noble Rat Mammary Gland and Uterotrophic Assays

Autor: J. P. Van Miller, J. Odum, R. L. Joiner, I. T. G. Pyrah, Jeff Foster, John Ashby

Publikováno v: Regulatory Toxicology and Pharmacology. 29:184-195

Colerangle and Roy (1996, Endocrine 4, 115-122) have described the apparent ability of both diethylstilbestrol (DES) and p-nonylphenol (NP) to cause extensive cell proliferation and lobular development in the mammary glands of young adult Noble rats.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0128c098ea39d38c35b7e3f54a0d5db3
https://doi.org/10.1006/rtph.1999.1286

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