Zobrazeno 1 - 10 of 29 pro vyhledávání: '"R. L. Danner"'
1
Effects of l-NMMA and Fluid Loading on TNF-induced Cardiovascular Dysfunction in Dogs
Autor: Peter Q. Eichacker, Robert E. Cunnion, R L Danner, Waheedullah Karzai, J. P. Cobb, Zenaide M.N. Quezado, Bradley D. Freeman, Liang Yan, Charles Natanson, Steven M. Banks, Jonathan E. Sevransky, M. J. N. Quezado
Publikováno v: American Journal of Respiratory and Critical Care Medicine. 157:1397-1405
We investigated the effects of N(omega)-monomethyl-L-arginine (L-NMMA) and fluid loading on tumor necrosis factor (TNF)-induced cardiovascular dysfunction in awake dogs. L-NMMA (40 mg x kg(-1) given intravenously over a period of 10 min, and followed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c993677b79b146b68b3a5a782290eb1d
https://doi.org/10.1164/ajrccm.157.5.9706100
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2
Human polymorphonuclear leukocytes lack detectable nitric oxide synthase activity
Autor: L Yan, R W Vandivier, A F Suffredini, R L Danner
Publikováno v: The Journal of Immunology. 153:1825-1834
Nitric oxide regulates polymorphonuclear leukocyte (PMN) function, but whether or not human PMNs express nitric oxide synthase (NOS) activity is controversial. We studied NOS activity in human PMNs by using human aortic endothelial cells (HAECs) for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::440a70b9afa97aa68a2194a96336de36
https://doi.org/10.4049/jimmunol.153.4.1825
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3
Nitric oxide regulates endotoxin-induced TNF-alpha production by human neutrophils
Autor: A L Van Dervort, L Yan, P J Madara, J P Cobb, R A Wesley, C C Corriveau, M M Tropea, R L Danner
Publikováno v: The Journal of Immunology. 152:4102-4109
We studied the effect of nitric oxide on LPS-induced TNF-alpha production by human neutrophils. Human neutrophils exposed to LPS and IFN-gamma did not show measurable increases in intracellular cyclic GMP (cGMP). However, cGMP increased upto 30-fold
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfad1dd2d87ef6dcce3d923fc439ef77
https://doi.org/10.4049/jimmunol.152.8.4102
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4
Cooperative and redundant signaling of leukotriene B4 and leukotriene D4 in human monocytes
Autor: L Y, Chen, M, Eberlein, S, Alsaaty, A, Martinez-Anton, J, Barb, P J, Munson, R L, Danner, Y, Liu, C, Logun, J H, Shelhamer, G, Woszczek
Publikováno v: Allergy. 66(10)
Leukotriene B(4) (LTB(4)) and cysteinyl leukotrienes (cysLTs) are important immune mediators, often found concomitantly at sites of inflammation. Although some of the leukotriene-mediated actions are distinctive (e.g., bronchial constriction for cysL
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ea212d92ec81a9e2d8c6c4683c156f3
https://pubmed.ncbi.nlm.nih.gov/21605126
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5
Neutrophil attractant protein-1 and monocyte chemoattractant protein-1 in human serum. Effects of intravenous lipopolysaccharide on free attractants, specific IgG autoantibodies and immune complexes
Autor: I Sylvester, A F Suffredini, A J Boujoukos, G D Martich, R L Danner, T Yoshimura, E J Leonard
Publikováno v: The Journal of Immunology. 151:3292-3298
We recently found that normal human sera contain IgG antibodies against two chemoattractants, neutrophil attractant protein-1 (NAP-1/IL-8) and monocyte chemoattractant protein-1 (MCP-1), as well as immune complexes of these proteins. Intravenously ad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4db6d5777496a2cade51c04d2c9da3c1
https://doi.org/10.4049/jimmunol.151.6.3292
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6
Shock and Multiple-Organ Dysfunction after Self-Administration of Salmonella Endotoxin
Autor: F S Chuidian, R L Danner, H C Kaulbach, A F Suffredini, A M Taveira da Silva, D R Lambert
Publikováno v: New England Journal of Medicine. 328:1457-1460
Endotoxin, a lipopolysaccharide component of the outer membrane of gram-negative bacteria, is involved in the pathogenesis of septic shock, but it is unclear whether endotoxin alone is capable of causing all the manifestations of the septic shock syn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f39f018f9190de370bb54415bdbe46de
https://doi.org/10.1056/nejm199305203282005
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8
Antagonism of lipopolysaccharide-induced priming of human neutrophils by lipid A analogs
Autor: A L Van Dervort, M E Doerfler, P Stuetz, R L Danner
Publikováno v: The Journal of Immunology. 149:359-366
Lipid X, a monosaccharide precursor of the lipid A component of LPS, has been found to antagonize LPS-induced priming of human neutrophils in a manner consistent with competitive inhibition. In this investigation, the inhibition of neutrophil priming
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::091058e2ed0c1e2d96313f3148c5e0dd
https://doi.org/10.4049/jimmunol.149.1.359
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10
Down-regulation of nitric oxide production by ibuprofen in human volunteers
Autor: R W, Vandivier, A, Eidsath, S M, Banks, H L, Preas, S B, Leighton, P J, Godin, A F, Suffredini, R L, Danner
Publikováno v: The Journal of pharmacology and experimental therapeutics. 289(3)
Ibuprofen has been shown in vitro to modulate production of nitric oxide (NO), a mediator of sepsis-induced hypotension. We sought to determine whether ibuprofen alters NO production and, thereby, vascular tone, in normal and endotoxin-challenged vol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fa9db31036e768bd9b000797c3ae518
https://pubmed.ncbi.nlm.nih.gov/10336532
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