Zobrazeno 1 - 10
of 1 761
pro vyhledávání: '"R. Kost"'
Autor:
Xue Yang, Zexuan Liu, Weiwei Tang, Uday P. Pratap, Alexia B. Collier, Kristin A. Altwegg, Rahul Gopalam, Xiaonan Li, Yaxia Yuan, Daohong Zhou, Zhao Lai, Yidong Chen, Gangadhara R. Sareddy, Philip T. Valente, Edward R. Kost, Suryavathi Viswanadhapalli, Ratna K. Vadlamudi
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2136-2156 (2024)
Endometrial carcinoma (ECa) is the fourth most common cancer among women. The oncogene PELP1 is frequently overexpressed in a variety of cancers, including ECa. We recently generated SMIP34, a small‐molecule inhibitor of PELP1 that suppresses PELP1
Externí odkaz:
https://doaj.org/article/004752a72a024ab7b87a815d9b033c3e
Autor:
Behnam Ebrahimi, Suryavathi Viswanadhapalli, Uday P. Pratap, Gopalam Rahul, Xue Yang, Prabhakar Pitta Venkata, Viktor Drel, Bindu Santhamma, Swapna Konda, Xiaonan Li, Alondra Lee Rodriguez Sanchez, Hui Yan, Gangadhara R. Sareddy, Zhenming Xu, Brij B. Singh, Philip T. Valente, Yidong Chen, Zhao Lai, Manjeet Rao, Edward R. Kost, Tyler Curiel, Rajeshwar R. Tekmal, Hareesh B. Nair, Ratna K. Vadlamudi
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract Of all gynecologic cancers, epithelial-ovarian cancer (OCa) stands out with the highest mortality rates. Despite all efforts, 90% of individuals who receive standard surgical and cytotoxic therapy experience disease recurrence. The precise m
Externí odkaz:
https://doaj.org/article/9ac36726d5db494b89c1884b726a9b5c
Autor:
Nicole M. Spencer, Lois Randolph, Alondra L. Rodriguez Sanchez, Hareesh B. Nair, Edward R. Kost, Ratna K. Vadlamudi, Suryavathi Viswanadhapalli
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp S2- (2023)
Objectives: Endometrial cancer is the most common gynecologic malignancy in women. Of the two histological subtypes of endometrial cancer described, Type II tumors are biologically more aggressive and convey a less favorable prognosis when compared t
Externí odkaz:
https://doaj.org/article/4254f7d22aeb4635966b0d8a2201d01e
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp S19- (2023)
Objectives: The purpose of this study is to describe the impact of paracrine signaling of plasminogen activator inhibitor-1 (PAI-1) and interleukin-6 (IL-6) on endometrial epithelial junctional proteins in an obese microenvironment in order to gain i
Externí odkaz:
https://doaj.org/article/323b90a4727b4989a1c6c2e27ff43747
Autor:
Logan Blankenship, Yasmin A. Lyons, Haisar Dao Campi, Philip T. Valente, Laura Barnes, Edward R. Kost
Publikováno v:
Gynecologic Oncology Reports, Vol 36, Iss , Pp 100772- (2021)
Externí odkaz:
https://doaj.org/article/41851586150a4df98b22fba09d80101a
Publikováno v:
Gynecologic Oncology Reports, Vol 17, Iss C, Pp 45-48 (2016)
Externí odkaz:
https://doaj.org/article/ed3bf07482914216aa09ac30f34ef0d4
Autor:
Lois Randolph, Alondra Rodriguez Sanchez, Logan Blankenship, Uday P. Pratap, Xue Yang, Durga Meenakshi Panneerdoss, Swapna Konda, Bindu Santhamma, Gangadhara R. Sareddy, Manjeet K. Rao, Edward R. Kost, Rajeshwar R. Tekmal, Hareesh B. Nair, Ratna K. Vadlamudi, Suryavathi Viswanadhapalli
Publikováno v:
Cancer Research. 83:3408-3408
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer (BC) that accounts for a disproportionate amount of BC mortality. The relationship(s) between obesity and the TNBC is crucial because the obesity prevalence in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f05494aff063998d191947bec922a56
https://doi.org/10.1158/1538-7445.am2023-3408
https://doi.org/10.1158/1538-7445.am2023-3408
Autor:
Alexia B. Collier, Suryavathi Viswanadhapalli, Tae-Kyung Lee, Kara Kassees, Karla Parra, Gaurav Sharma, Tanner Reese, Michael Hsieh, Xihui Liu, Xue Yang, Behnam Ebrahimi, Uday P. Pratap, Rahul Gopalam, Chia Yuan Chen, Scott Terry Elmore, Gangadhara Reddy Sareddy, Edward R. Kost, Jung-Mo Ahn, Ganesh V. Raj, Ratna K. Vadlamudi
Publikováno v:
Cancer Research. 83:3986-3986
BACKGROUND: Ovarian cancer (OCa) is the deadliest of all gynecologic cancers in the United States. Currently approved therapies have improved OCa survival for clinically localized disease, however, the majority (~90%) of patients with high-grade sero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be4a46f6e8f3153a5dc65e0047244b15
https://doi.org/10.1158/1538-7445.am2023-3986
https://doi.org/10.1158/1538-7445.am2023-3986
Autor:
Behnam Ebrahimi, Suryavathi Viswanadhapalli, Uday P. Pratap, Rahul Gopalam, Xue Yang, Bindhu Santhamma, Swapna Konda, Xiaonan Li, Hui Yan, Gangadhara R. Sareddy, Zhenming Xu, Edward R. Kost, Rajeshwar R. Tekmal, Hareesh B. Nair, Ratna K. Vadlamudi
Publikováno v:
Cancer Research. 83:4966-4966
Background: Of all gynecologic cancers, ovarian cancer (OCa) has the highest mortality rates. Nearly 90% of patients who receive standard surgical and cytotoxic treatment experience disease recurrence. Leukemia inhibitory factor (LIF) and its recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6badb0c7e16a2cd9914d450296594680
https://doi.org/10.1158/1538-7445.am2023-4966
https://doi.org/10.1158/1538-7445.am2023-4966
Autor:
Logan Blankenship, Uday P. Pratap, Xue Yang, Zexuan Liu, Kristin A. Altwegg, Bindu Santhamma, Kumaraguruparan Ramasamy, Swapna Konda, Yidong Chen, Zhao Lai, Siyuan Zheng, Gangadhara R. Sareddy, Philip T. Valente, Edward R. Kost, Hareesh B. Nair, Rajeshwar R. Tekmal, Ratna K. Vadlamudi, Suryavathi Viswanadhapalli
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5400
Endometrial cancer (EC) is the fourth most common cancer in women, and half of the endometrioid EC (EEC) cases are attributable to obesity. However, the underlying mechanism(s) of obesity-driven EEC remain(s) unclear. In this study, we examined wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28369240cb4f9b1666aa15c60b328fc3