Zobrazeno 1 - 10
of 88
pro vyhledávání: '"R. Kopparapu"'
Autor:
Bach D. Nguyen, Brenna L. Stevens, Daniel J. Elson, Darren Finlay, John T. Gamble, Prasad R. Kopparapu, Robyn L. Tanguay, Andrew B. Buermeyer, Nancy I. Kerkvliet, Siva K. Kolluri
Publikováno v:
The FEBS Journal. 290:2064-2084
Autor:
Wade T. Iams, MD, Prasad R. Kopparapu, PhD, Yingjun Yan, MS, Anel Muterspaugh, MPH, Zhiguo Zhao, MS, Heidi Chen, PhD, Christopher Cann, MD, Sally York, MD, PhD, Leora Horn, MD, MS, Kristin Ancell, MD, Kenneth Wyman, MD, Caterina Bertucci, MPA, Tristan Shaffer, MS, Lauren A. Hodsdon, MPH, Kavita Garg, PhD, Seyed Ali Hosseini, MD, PhD, Lee P. Lim, PhD, Christine M. Lovly, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 1, Iss 2, Pp 100024- (2020)
Introduction: Most patients (70%) with limited-stage SCLC (LS-SCLC) who are treated with curative-intent therapy suffer disease relapse and cancer-related death. We evaluated circulating tumor DNA (ctDNA) as a predictor of disease relapse and death a
Externí odkaz:
https://doaj.org/article/4458f029679347a28119d2847325d282
Autor:
D. Kossakowski, M. Kürster, T. Trifonov, Th. Henning, J. Kemmer, J. A. Caballero, R. Burn, S. Sabotta, J. S. Crouse, T. J. Fauchez, E. Nagel, A. Kaminski, E. Herrero, E. Rodríguez, E. González-Álvarez, A. Quirrenbach, P. J. Amado, I. Ribas, A. Reiners, J. Aceituno, V. J. S. Béjar, D. Baroch, S. T. Bastelberger, P. Chaturvedi, C. Cifuentes, S. Dreizler, S. V. Jeffers, R. Kopparapu, M. Lafarga, M. J. López-González, S. Martín-Ruiz, D. Montes, J. C. Morales, E. Pallé, A. Pavlov, S. Pedraz, V. Perdelwitz, M. Pérez-Torres, M. Perger, S. Reffert, C. Rodríguez López, M. Schlecker, P. Schöfer, A. Schweitzer, Y. Shan, A. Shields, S. Stock, E. Wolf, M. R. Zapatero Osorio, M. Zechmeister
Publikováno v:
Astronomy and Astrophysics
We present the discovery of an Earth-mass planet ($M_b\sin i = 1.26\pm0.21M_\oplus$) on a 15.6d orbit of a relatively nearby ($d\sim$9.6pc) and low-mass ($0.167\pm0.011 M_\odot$) M5.0V star, Wolf 1069. Sitting at a separation of $0.0672\pm0.0014$au a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0f6c669db9fb87600abf790cc0e855
https://hdl.handle.net/21.11116/0000-000C-AB8F-3
https://hdl.handle.net/21.11116/0000-000C-AB8F-3
Akademický článek
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Autor:
Prasad R. Kopparapu, Melinda Duplessis, Edward Lo, Yingjun Yan, Wade T. Iams, Josh Nordberg, Arturo Ramirez, Tad George, Christine Lovly
Publikováno v:
Cancer Research. 82:3375-3375
Background: Recently, a new molecular classification of small cell lung cancer (SCLC), defined by expression of four key transcription regulators - ASCL1, NEUROD1, YAP1 and POU2F3 - has been proposed. These molecular subtypes may confer differential
Autor:
Cindy Lowe, Darren R. Tyson, Portia L. Thomas, Yun Kai Zhang, Shamilene Sivagnanam, Sarah M. Groves, Qi Liu, Kelli L. Boyd, Wade T. Iams, Hua Chang Chen, Jia Li, Lisa M. Coussens, Vito Quaranta, Yingjun Yan, Prasad R. Kopparapu, Paula Gonzalez-Ericsson, Courtney Betts, Christine M. Lovly, Heidi Chen
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 16(7)
The programmed death-ligand 1 (PD-L1) immune checkpoint inhibitors, atezolizumab and durvalumab, have received regulatory approval for the first-line treatment of patients with extensive-stage SCLC. Nevertheless, when used in combination with platinu
Autor:
Prasad R. Kopparapu, Tristan Shaffer, Anel Muterspaugh, Christopher G. Cann, Kenneth Wyman, Lauren Hodsdon, Heidi Chen, Wade T. Iams, Zhiguo Zhao, Yingjun Yan, Sally York, Leora Horn, Lee P. Lim, Kavita Garg, Christine M. Lovly, Kristin K. Ancell, Seyed Ali Hosseini, Caterina Bertucci
Publikováno v:
JTO Clinical and Research Reports, Vol 1, Iss 2, Pp 100024-(2020)
JTO Clinical and Research Reports
JTO Clinical and Research Reports
Introduction Most patients (70%) with limited-stage SCLC (LS-SCLC) who are treated with curative-intent therapy suffer disease relapse and cancer-related death. We evaluated circulating tumor DNA (ctDNA) as a predictor of disease relapse and death af
Autor:
Dhairya A. Lakhani, Wade T. Iams, Karinna Almodovar, Christien Kluwe, Aneri B. Balar, Evan C. Osmundson, Leora Horn, S. Antic, Prasad R. Kopparapu, Anel Muterspaugh, Jarrod T. Smith, Zhiguo Zhao, Seyed Ali Hosseini, Lauren Hodsdon, Lee Lim, Christine M. Lovly, Caterina Bertucci, Pierre P. Massion, Kavita Garg, Yingjun Yan, Sally York, Tristan Shaffer
Publikováno v:
JTO Clinical and Research Reports
JTO Clinical and Research Reports, Vol 2, Iss 3, Pp 100110-(2021)
JTO Clinical and Research Reports, Vol 2, Iss 3, Pp 100110-(2021)
Introduction: Blood-based next-generation sequencing assays of circulating tumor DNA (ctDNA) have the ability to detect tumor-associated mutations in patients with SCLC. We sought to characterize the relationship between ctDNA mean variant allele fre
Autor:
Robert D. Hoffman, Suman R. Das, Melissa A. Warren, Cindy Lowe, Madan Jagasia, Kelli L. Boyd, Justin M. Balko, Paula I. Gonzalez-Ericsson, Hunter M. Brown, Meghan E. Kapp, Michael J. Noto, Brent Sterling, Wade T. Iams, Prasad R. Kopparapu, Brian I. Rini, Christine M. Lovly, Douglas B. Johnson
Publikováno v:
medRxiv
Immune checkpoint inhibitors (ICIs) are used for the treatment of numerous cancers, but risks associated with ICI-therapy during the COVID-19 pandemic are poorly understood. We report a case of acute lung injury in a lung cancer patient initially tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0444d6fcdf305d6a7a334d57d1ef336
https://doi.org/10.1101/2020.04.29.20085738
https://doi.org/10.1101/2020.04.29.20085738
Autor:
Edmond F O'Donnell, Katerine S Saili, Daniel C Koch, Prasad R Kopparapu, David Farrer, William H Bisson, Lijoy K Mathew, Sumitra Sengupta, Nancy I Kerkvliet, Robert L Tanguay, Siva Kumar Kolluri
Publikováno v:
PLoS ONE, Vol 5, Iss 10 (2010)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiat
Externí odkaz:
https://doaj.org/article/ff6d993d8c44450790b18bd377768fa9