Zobrazeno 1 - 10
of 438
pro vyhledávání: '"R. Kohnen"'
Autor:
Ruiyang Liu, Qingsong Gao, Steven M. Foltz, Jared S. Fowles, Lijun Yao, Julia Tianjiao Wang, Song Cao, Hua Sun, Michael C. Wendl, Sunantha Sethuraman, Amila Weerasinghe, Michael P. Rettig, Erik P. Storrs, Christopher J. Yoon, Matthew A. Wyczalkowski, Joshua F. McMichael, Daniel R. Kohnen, Justin King, Scott R. Goldsmith, Julie O’Neal, Robert S. Fulton, Catrina C. Fronick, Timothy J. Ley, Reyka G. Jayasinghe, Mark A. Fiala, Stephen T. Oh, John F. DiPersio, Ravi Vij, Li Ding
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Clonal evolution in multiple myeloma (MM) needs to be understood in both the tumor and its microenvironment. Here the authors perform single-cell multi-omics profiling of samples from MM patients at different stages, finding transitions in the immune
Externí odkaz:
https://doaj.org/article/55db7fd3140a43c78fdc7b490f24992e
Autor:
Steven M. Foltz, Qingsong Gao, Christopher J. Yoon, Hua Sun, Lijun Yao, Yize Li, Reyka G. Jayasinghe, Song Cao, Justin King, Daniel R. Kohnen, Mark A. Fiala, Li Ding, Ravi Vij
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Multiple myeloma is characterised by frequent gene fusions. Here, the authors use data from the Multiple Myeloma Research Foundation CoMMpass Study to further investigate fusion genes in this disease and their clinical relevance.
Externí odkaz:
https://doaj.org/article/2a4adbc95da54e6daefbf479c5c03fa9
Autor:
Erica K. Barnell, Zachary L. Skidmore, Kenneth F. Newcomer, Monique Chavez, Katie M. Campbell, Kelsy C. Cotto, Nicholas C. Spies, Marianna B. Ruzinova, Tianjiao Wang, Brooj Abro, Friederike Kreisel, Bijal A. Parikh, Eric J. Duncavage, John L. Frater, Yi-Shan Lee, Anjum Hassan, Justin A. King, Daniel R. Kohnen, Mark A. Fiala, John S. Welch, Geoffrey L. Uy, Kiran Vij, Ravi Vij, Malachi Griffith, Obi L. Griffith, Lukas D. Wartman
Publikováno v:
Blood advances.
Patients with multiple myeloma (MM) who are treated with lenalidomide rarely develop a secondary B-cell acute lymphoblastic leukemia (B-ALL). The clonal and biological relationship between these sequential malignancies is not yet clear. We identified
Autor:
Robert S. Fulton, Matthew A. Wyczalkowski, Christopher J. Yoon, Justin King, Steven M. Foltz, Timothy J. Ley, Julie O'Neal, Ravi Vij, Erik Storrs, Ruiyang Liu, Amila Weerasinghe, Julia Tianjiao Wang, Scott R. Goldsmith, Hua Sun, Michael C. Wendl, Michael P. Rettig, Stephen T. Oh, Song Cao, Mark A. Fiala, Catrina Fronick, Daniel R. Kohnen, Sunantha Sethuraman, Lijun Yao, John F. DiPersio, Reyka G Jayasinghe, Jared S. Fowles, Joshua F. McMichael, Li Ding, Qingsong Gao
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Multiple myeloma (MM) is characterized by the uncontrolled proliferation of plasma cells. Despite recent treatment advances, it is still incurable as disease progression is not fully understood. To investigate MM and its immune environment, we apply
Autor:
Song Cao, Lijun Yao, Daniel R. Kohnen, Ravi Vij, Mark A. Fiala, Hua Sun, Li Ding, Reyka G Jayasinghe, Steven M. Foltz, Christopher J. Yoon, Qingsong Gao, Justin King, Yize Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Multiple myeloma is a plasma cell blood cancer with frequent chromosomal translocations leading to gene fusions. To determine the clinical relevance of fusion events, we detect gene fusions from a cohort of 742 patients from the Multiple Myeloma Rese
Autor:
Daniel R. Kohnen, Barbara Muz, Feda Azab, Justin King, Jennifer Sun, Abdel Kareem Azab, Ravi Vij, Amanda Jeske, Kinan Alhallak, Katherine Wasden
Publikováno v:
Blood. 136:3-3
Introduction: Multiple myeloma (MM) is a lymphoplasmacytic malignancy localized in the bone marrow (BM) characterized by the continuous metastasis. Despite the introduction of novel therapies, MM patients relapse due to the development of drug resist
Autor:
Stephen T. Oh, Michael P. Rettig, Jared S. Fowles, Julie O'Neal, Tianjiao Wang, Daniel Cui Zhou, Hua Sun, Daniel R. Kohnen, Reyka G Jayasinghe, Ravi Vij, Lijun Yao, John F. DiPersio, Li Ding, Ruiyang Liu, Mark A. Fiala
Publikováno v:
Blood. 134:364-364
Multiple myeloma (MM) is a hematological malignancy, defined by aberrant monoclonal proliferation of plasma cells in the bone marrow, that to date remains an incurable disease despite advances in treatment. Key genetic and epigenetic alterations that
Autor:
John F. DiPersio, Julie O'Neal, Chia-Feng Tsai, Mark A. Fiala, Hua Sun, Liu Tao, Ying Zhu, Smrithi Mani, Steven M. Foltz, Yige Wu, Catrina Fronick, Daniel R. Kohnen, Ruiyang Liu, Ravi Vij, Justin King, Reyka G Jayasinghe, Tianjiao Wang, Scott R. Goldsmith, Michael P. Rettig, Lijun Yao, Li Ding
Publikováno v:
Blood. 134:5531-5531
Multiple myeloma (MM) is a disease defined by clonal proliferation of abnormal plasma cells from B-cells. Improved treatments for MM have led to improving overall lifespan, but still remains incurable due to acquired resistance to therapy and tumor h
Autor:
I. Ahmed, A. Biswas, S. Krishnamurthy, P. Julka, G. Rath, M. Back, D. Huang, C. Gzell, J. Chen, M. Kastelan, P. Gaur, H. Wheeler, S. N. Badiyan, C. G. Robinson, J. R. Simpson, D. D. Tran, K. M. Rich, J. L. Dowling, M. R. Chicoine, E. C. Leuthardt, A. H. Kim, J. Huang, S. R. Michaelsen, I. J. Christensen, K. Grunnet, M.-T. Stockhausen, H. Broholm, M. Kosteljanetz, H. S. Poulsen, M. Tieu, E. Lovblom, M. Macnamara, W. Mason, D. Rodin, E. Tai, K. Ubhi, N. Laperriere, B.-A. Millar, C. Menard, B. Perkins, C. Chung, J. Clarke, A. Molinaro, J. Phillips, N. Butowski, S. Chang, A. Perry, J. Costello, A. DeSilva, J. Rabbitt, M. Prados, A. L. Cohen, C. Anker, D. Shrieve, B. Hall, K. Salzman, R. Jensen, H. Colman, O. Farber, U. Weinberg, Y. Palti, B. Fisher, H. Chen, D. Macdonald, G. Lesser, S. Coons, D. Brachman, S. Ryu, M. Werner-Wasik, J.-P. Bahary, A. Chakravarti, M. Mehta, T. Gupta, V. Nair, S. Epari, J. Godasastri, A. Moiyadi, P. Shetty, S. Juvekar, R. Jalali, U. Herrlinger, N. Schafer, J. Steinbach, A. Weyerbrock, P. Hau, R. Goldbrunner, R. Kohnen, H. Urbach, W. Stummer, M. Glas, C. Houillier, H. Ghesquieres, C. Chabrot, C. Soussain, G. Ahle, S. Choquet, P. Faurie, J.-O. Bay, J. Vargaftig, C. Gaultier, E. Nicolas-Virelizier, K. Hoang-Xuan, O. Iskanderani, F. Izar, A. Benouaich-Amiel, T. Filleron, E. Moyal, C. Iweha, S. Jain, E. Melian, A. Sethi, K. Albain, D. Shafer, B. Emami, X.-T. Kong, S. Green, E. Filka, R. Green, W. Yong, P. Nghiemphu, T. Cloughesy, A. Lai, S. Mallick, S. Roy, S. Purkait, S. Gupta, P. K. Julka, G. K. Rath, C. Marosi, J. Thaler, C. Ay, A. Kaider, E.-M. Reitter, J. Haselbock, M. Preusser, B. Flechl, C. Zielinski, I. Pabinger, S.-I. Miyatake, M. Furuse, T. Miyata, E. Yoritsune, S. Kawabata, T. Kuroiwa, Y. Muragaki, T. Maruyama, H. Iseki, J. Akimoto, S. Ikuta, M. Nitta, K. Maebayashi, T. Saito, Y. Okada, S. Kaneko, A. Matsumura, K. Karasawa, Y. Nakazato, T. Kayama, L. B. Nabors, K. L. Fink, T. Mikkelsen, D. Grujicic, R. Tarnawski, D.-H. Nam, M. Mazurkiewicz, M. Salacz, L. Ashby, L. Thurzo, V. Zagonel, R. Depenni, J. R. Perry, J. Henslee-Downey, M. Picard, D. A. Reardon, N. Nambudiri, L. Nayak, D. LaFrankie, P. Wen, D. Ney, J. Carlson, D. Damek, P. Blatchford, L. Gaspar, B. Kavanagh, A. Waziri, K. Lillehei, K. Reddy, C. Chen, I. Rashed, K. Barton, D. Anderson, V. Prabhu, R. Rusch, M. Belongia, M. Maheshwari, S. Firat, D. Schiff, A. Desjardins, M. Glantz, M. Chamberlain, W. Shapiro, S. Gopal, K. Judy, S. Patel, A. Mahapatra, J. Shan, D. Gupta, K. Shih, J. A. Bacha, D. Brown, W. J. Garner, A. Steino, R. Schwart, S. Kanekal, M. Li, L. Lopez, H. A. Burris, C. Soderberg-Naucler, A. Rahbar, G. Stragliotto, A. J. Song, A. M. S. Kumar, E. S. Murphy, T. Tekautz, J. H. Suh, V. Recinos, S. T. Chao, J. Spoor, K. Korami, J. Kloezeman, R. Balvers, C. Dirven, M. Lamfers, S. Leenstra, A. Sumrall, D. Haggstrom, A. Crimaldi, J. Symanowski, P. Giglio, A. Asher, S. Burri, G. Sunkersett, Z. Khatib, C. M. Prajapati, E. E. Magalona, M. Mariano, I. M. Sih, R. Torcuator, W. Taal, H. Oosterkamp, A. Walenkamp, L. Beerenpoot, M. Hanse, J. Buter, A. Honkoop, D. Boerman, F. de Vos, R. Jansen, F. van der Berkmortel, D. Brandsma, R. Enting, J. Kros, J. Bromberg, I. van Heuvel, M. Smits, R. van der Holt, R. Vernhout, M. van den Bent, W. Wick, C. Suarez, J. Rodon, P. Forsyth, I. Gueorguieva, A. Cleverly, T. Burkholder, D. Desaiah, M. Lahn, L. Zach, D. Guez, D. Last, D. Daniels, O. Nissim, Y. Grober, C. Hoffmann, D. Nass, A. Talianski, R. Spiegelmann, Z. Cohen, Y. Mardor
Publikováno v:
Neuro-Oncology. 15:iii75-iii84
Autor:
Daniel R. Kohnen, Adam D. Scott, Kuan-lin Huang, Fernanda Martins Rodrigues, Qingsong Gao, Justin King, John F. DiPersio, Mark A. Fiala, Ravi Vij, Li Ding, Steven M. Foltz
Publikováno v:
Blood. 132:4499-4499
Multiple myeloma (MM) is an incurable hematological malignancy characterized by the clonal proliferation of malignant plasma cells in the bone marrow. Like other cancers, MM is a genetically complex and heterogeneous disease. One of its distinctive c