Synthesis and evaluation of 1, 2, 3-triazole benzoate derivatives for inhibition of serine β-lactamases in extensively drug resistant pathogenic E. coli strains

Autor: Harshal S. Oman, Archana A. Kharat, Pramod S. Phatak, Kishan P. Haval, Jeetendra A. Kulkarni, Ganesh S. Kakde, Kiran R. Kharat, Dilip G. Kadam, Arun S. Kharat

Publikováno v: European Journal of Medicinal Chemistry Reports, Vol 9, Iss , Pp 100109- (2023)

The β-lactamase enzyme is a leading cause of drug resistance developed by bacteria. The combination of β-lactam (BL) antibiotics with an appropriate β-lactamase inhibitor (BLI) is a fundamental approach used to circumvent the problem of β-lactama

Externí odkaz: https://doaj.org/article/8d0487cc99654e3aab8b6a77d88607e3

Impacts of biomedical hashtag-based Twitter campaign: #DHPSP utilization for promotion of open innovation in digital health, patient safety, and personalized medicine

Autor: Maria Kletecka-Pulker, Himel Mondal, Dongdong Wang, R. Gonzalo Parra, Abdulkadir Yusif Maigoro, Soojin Lee, Tushar Garg, Eoghan J. Mulholland, Hari Prasad Devkota, Bikramjit Konwar, Sourav S. Patnaik, Ronan Lordan, Faisal A. Nawaz, Christos Tsagkaris, Rehab A. Rayan, Anna Maria Louka, Ronita De, Pravin Badhe, Eva Schaden, Harald Willschke, Mathias Maleczek, Hemanth Kumar Boyina, Garba M. Khalid, Md. Sahab Uddin, Sanusi, Johra Khan, Joy I. Odimegwu, Andy Wai Kan Yeung, Faizan Akram, Chandragiri Siva Sai, Sherri Bucher, Shravan Kumar Paswan, Rajeev K. Singla, Bairong Shen, Sara Di Lonardo, Anela Tosevska, Jesus Simal-Gandara, Manja Zec, Elena González-Burgos, Marija Habijan, Maurizio Battino, Francesca Giampieri, Aleksei Tikhonov, Danila Cianciosi, Tamara Y. Forbes-Hernandez, José L. Quiles, Bruno Mezzetti, Smith B. Babiaka, Mosa E.O. Ahmed, Paula Piccard, Mágali S. Urquiza, Jennifer R. Depew, Fabien Schultz, Daniel Sur, Sandeep R. Pai, Mihnea-Alexandru Găman, Merisa Cenanovic, Nikolay T. Tzvetkov, Surya Kant Tripathi, Kiran R. Kharat, Alfonso T. Garcia-Sosa, Simon Sieber, Atanas G. Atanasov

Publikováno v: Current Research in Biotechnology, Vol 3, Iss , Pp 146-153 (2021)

The open innovation hub Digital Health and Patient Safety Platform (DHPSP) was recently established with the purpose to invigorate collaborative scientific research and the development of new digital products and personalized solutions aiming to impr

Externí odkaz: https://doaj.org/article/965a7e1b50a24b18b2ad75c2b5f21ad1

The Calotropis Gigantea Methanolic Extract Induces Apoptosis in Human Breast Carcinoma Cells

Autor: Kiran R. Kharat, Arun S. Kharat

Publikováno v: Iranian Journal of Medical Sciences, Vol 44, Iss 6, Pp 483-492 (2019)

Background: Calotropis gigantea (family: Asclepiadaceae) has been known to contain cardiac glycosides. The C. gigantea extracts have been reported as cytotoxic to a few cancer cell lines. The present study was designed to examine the effect of Calotr

Externí odkaz: https://doaj.org/article/29cd938b02814331a89fcdda09cfd6e6

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Autor: Rajeev K. Singla, Ronita De, Thomas Efferth, Bruno Mezzetti, Md. Sahab Uddin, null Sanusi, Fidele Ntie-Kang, Dongdong Wang, Fabien Schultz, Kiran R. Kharat, Hari Prasad Devkota, Maurizio Battino, Daniel Sur, Ronan Lordan, Sourav S Patnaik, Christos Tsagkaris, Chandragiri Siva Sai, Surya Kant Tripathi, Mihnea-Alexandru Găman, Mosa E.O. Ahmed, Elena González-Burgos, Smith B. Babiaka, Shravan Kumar Paswan, Joy Ifunanya Odimegwu, Faizan Akram, Jesus Simal-Gandara, Mágali S. Urquiza, Aleksei Tikhonov, Himel Mondal, Shailja Singla, Sara Di Lonardo, Eoghan J Mulholland, Merisa Cenanovic, Abdulkadir Yusif Maigoro, Francesca Giampieri, Soojin Lee, Nikolay T. Tzvetkov, Anna Maria Louka, Pritt Verma, Hitesh Chopra, Scarlett Perez Olea, Johra Khan, José M. Alvarez Suarez, Xiaonan Zheng, Michał Tomczyk, Manoj Kumar Sabnani, Christhian Delfino Villanueva Medina, Garba M. Khalid, Hemanth Kumar Boyina, Milen I. Georgiev, Claudiu T. Supuran, Eduardo Sobarzo-Sánchez, Tai-Ping Fan, Valeria Pittala, Antoni Sureda, Nady Braidy, Gian Luigi Russo, Rosa Anna Vacca, Maciej Banach, Gérard Lizard, Amira Zarrouk, Sonia Hammami, Ilkay Erdogan Orhan, Bharat B. Aggarwal, George Perry, Mark JS Miller, Michael Heinrich, Anupam Bishayee, Anake Kijjoa, Nicolas Arkells, David Bredt, Michael Wink, Bernd l. Fiebich, Gangarapu Kiran, Andy Wai Kan Yeung, Girish Kumar Gupta, Antonello Santini, Massimo Lucarini, Alessandra Durazzo, Amr El-Demerdash, Albena T. Dinkova-Kostova, Alejandro Cifuentes, Eliana B. Souto, Muhammad Asim Masoom Zubair, Pravin Badhe, Javier Echeverría, Jarosław Olav Horbańczuk, Olaf K. Horbanczuk, Helen Sheridan, Sadeeq Muhammad Sheshe, Anna Maria Witkowska, Ibrahim M. Abu-Reidah, Muhammad Riaz, Hammad Ullah, Akolade R. Oladipupo, Víctor Lopez, Neeraj Kumar Sethiya, Bhupal Govinda Shrestha, Palaniyandi Ravanan, Subash Chandra Gupta, Qushmua E. Alzahrani, Preethidan Dama Sreedhar, Jianbo Xiao, Mohammad Amin Moosavi, Parasuraman Aiya Subramani, Amit Kumar Singh, Ananda Kumar Chettupalli, Jayanta Kumar Patra, Gopal Singh, Tomasz M. Karpiński, Fuad Al-Rimawi, Rambod Abiri, Atallah F. Ahmed, Davide Barreca, Sharad Vats, Said Amrani, Carmela Fimognari, Andrei Mocan, Lucian Hritcu, Prabhakar Semwal, Md. Shiblur Rahaman, Mila Emerald, Akinleye Stephen Akinrinde, Abhilasha Singh, Ashima Joshi, Tanuj Joshi, Shafaat Yar Khan, Gareeballah Osman Adam Balla, Aiping Lu, Sandeep Ramchandra Pai, Imen Ghzaiel, Niyazi Acar, Nour Eddine Es-Safi, Gokhan Zengin, Azazahemad A. Kureshi, Arvind Kumar Sharma, Bikash Baral, Neeraj Rani, Philippe Jeandet, Monica Gulati, Bhupinder Kapoor, Yugal Kishore Mohanta, Zahra Emam-Djomeh, Raphael Onuku, Jennifer R. Depew, Omar M. Atrooz, Bey Hing Goh, Jose Carlos Andrade, Bikramjit Konwar, VJ Shine, João Miguel Lousa Dias Ferreira, Jamil Ahmad, Vivek K. Chaturvedi, Krystyna Skalicka-Woźniak, Rohit Sharma, Rupesh K. Gautam, Sebastian Granica, Salvatore Parisi, Rishabh Kumar, Atanas G. Atanasov, Bairong Shen

Publikováno v: Singla, R K, De, R, Efferth, T, Mezzetti, B, Sahab Uddin, M, Sanusi, Ntie-Kang, F, Wang, D, Schultz, F, Kharat, K R, Devkota, H P, Battino, M, Sur, D, Lordan, R, Patnaik, S S, Tsagkaris, C, Sai, C S, Tripathi, S K, Găman, M-A, Ahmed, M E O, González-Burgos, E, Babiaka, S B, Paswan, S K, Odimegwu, J I, Akram, F, Simal-Gandara, J, Urquiza, M S, Tikhonov, A, Mondal, H, Singla, S, Lonardo, S D, Mulholland, E J, Cenanovic, M, Maigoro, A Y, Giampieri, F, Lee, S, Tzvetkov, N T, Louka, A M, Verma, P, Chopra, H, Olea, S P, Khan, J, Alvarez Suarez, J M, Zheng, X, Tomczyk, M, Sabnani, M K, Medina, C D V, Khalid, G M, Boyina, H K, Georgiev, M I, Supuran, C T, Sobarzo-Sánchez, E, Fan, T-P, Pittala, V, Sureda, A, Braidy, N, Russo, G L, Vacca, R A, Banach, M, Lizard, G, Zarrouk, A, Hammami, S, Orhan, I E, Aggarwal, B B, Perry, G, Miller, M J, Heinrich, M, Bishayee, A, Kijjoa, A, Arkells, N, Bredt, D, Wink, M, Fiebich, B L, Kiran, G, Yeung, A W K, Gupta, G K, Santini, A, Lucarini, M, Durazzo, A, El-Demerdash, A, Dinkova-Kostova, A T, Cifuentes, A, Souto, E B, Zubair, M A M, Badhe, P, Echeverría, J, Horbańczuk, J O, Horbanczuk, O K, Sheridan, H, Sheshe, S M, Witkowska, A M, Abu-Reidah, I M, Riaz, M, Ullah, H, Oladipupo, A R, Lopez, V, Sethiya, N K, Shrestha, B G, Ravanan, P, Gupta, S C, Alzahrani, Q E, Dama Sreedhar, P, Xiao, J, Moosavi, M A, Subramani, P A, Singh, A K, Chettupalli, A K, Patra, J K, Singh, G, Karpiński, T M, Al-Rimawi, F, Abiri, R, Ahmed, A F, Barreca, D, Vats, S, Amrani, S, Fimognari, C, Mocan, A, Hritcu, L, Semwal, P, Shiblur Rahaman, M, Emerald, M, Akinrinde, A S, Singh, A, Joshi, A, Joshi, T, Khan, S Y, Balla, G O A, Lu, A, Pai, S R, Ghzaiel, I, Acar, N, Es-Safi, N E, Zengin, G, Kureshi, A A, Sharma, A K, Baral, B, Rani, N, Jeandet, P, Gulati, M, Kapoor, B, Mohanta, Y K, Emam-Djomeh, Z, Onuku, R, Depew, J R, Atrooz, O M, Goh, B H, Andrade, J C, Konwar, B, Shine, V J, Ferreira, J M L D, Ahmad, J, Chaturvedi, V K, Skalicka-Woźniak, K, Sharma, R, Gautam, R K, Granica, S, Parisi, S, Kumar, R, Atanasov, A G & Shen, B 2023, ' The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis ', Phytomedicine : international journal of phytotherapy and phytopharmacology, vol. 108, 154520 . https://doi.org/10.1016/j.phymed.2022.154520

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platfor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021478af0b1ead3804b2a1f4e86ad29c
https://avesis.gazi.edu.tr/publication/details/e1cf0bb8-5a83-4131-83fb-892c34a23e19/oai

Current Approaches in the Management and Treatment of Polycystic Ovary Syndrome: A Comprehensive Review

Autor: Amol R. Kharat, Manisha K. Pakhare, Kiran R. Kharat

Polycystic ovarian syndrome (PCOS), is a hormonal and endocrine condition among women most frequent among teenagers and young women, affecting 5-10% of women throughout their reproductive years and characterized by an imbalance of female sex hormones

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a525b85cb27ed2090f401a4ae3045f02