Zobrazeno 1 - 10
of 35
pro vyhledávání: '"R. Keith Duncan"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Cyclodextrins are a family of cyclic oligosaccharides with widespread usage in medicine, industry and basic sciences owing to their ability to solubilize and stabilize guest compounds. In medicine, cyclodextrins primarily act as a complexing vehicle
Externí odkaz:
https://doaj.org/article/c8d92bc296614ef1806a5d190d782e78
Autor:
Ellen K. W. Brennan, R. Keith Duncan
Publikováno v:
Teaching Science Students to Communicate: A Practical Guide ISBN: 9783030916275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0781fab22d789def1384b6a4a641e35
https://doi.org/10.1007/978-3-030-91628-2_51
https://doi.org/10.1007/978-3-030-91628-2_51
Autor:
R. Keith Duncan, Lisa L. Kabara, Donald L. Swiderski, Young Ho Kim, Yehoash Raphael, Min Young Lee
Publikováno v:
Journal of Audiology & Otology
Background and objectives The antioxidant ebselen will be able to limit or prevent the ototoxicity arising from 2-hydroxypropyl-β-cyclodextrin (HPβCD). Niemann-Pick Type C (NPC) disease is a disorder of lysosomal storage manifested in sphingolipido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8259174d55835623f27e0c4dbfcc13c7
http://europepmc.org/articles/PMC6468279
http://europepmc.org/articles/PMC6468279
Autor:
Ciria C. Hernandez, Rahilla A. Tarfa, Jose M. I. Limcaoco, Ruiting Liu, Pravat Mondal, Clare Hill, R. Keith Duncan, Thanos Tzounopoulos, Corey R. J. Stephenson, Matthew J. O’Meara, Peter Wipf
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 71:128841
To identify pore domain ligands on Kv7.2 potassium ion channels, we compared wild-type (WT) and W236L mutant Kv7.2 channels in a series of assays with previously validated and novel agonist chemotypes. Positive controls were retigabine, flupirtine, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5dc09deaa734e0a650ae27d1f2d1d5e
https://doi.org/10.1016/j.bmcl.2022.128841
https://doi.org/10.1016/j.bmcl.2022.128841
Autor:
Can Wang, Maohua Zheng, Adam J. Iliff, Xia Li, Jianfeng Liu, Alison Hake, Yuling Guo, Xinxing Zhang, X.Z. Shawn Xu, Karl Grosh, Elizabeth A. Ronan, R. Keith Duncan
Publikováno v:
Neuron
SUMMARY Unlike olfaction, taste, touch, vision, and proprioception, which are widespread across animal phyla, hearing is found only in vertebrates and some arthropods. The vast majority of invertebrate species are thus considered insensitive to sound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd48f22f515883c2a0708e44ee66fe7
http://europepmc.org/articles/PMC8602785
http://europepmc.org/articles/PMC8602785
Publikováno v:
Journal of the Association for Research in Otolaryngology. 16:599-611
Cyclodextrins are simple yet powerful molecules widely used in medicinal formulations and industry for their ability to stabilize and solubilize guest compounds. However, recent evidence shows that 2-hydroxypropyl-β-cyclodextrin (HPβCD) causes seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e70595fd64d8c37505c720e1c56e9bd
https://doi.org/10.1007/s10162-015-0528-6
https://doi.org/10.1007/s10162-015-0528-6
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Cyclodextrins are a family of cyclic oligosaccharides with widespread usage in medicine, industry and basic sciences owing to their ability to solubilize and stabilize guest compounds. In medicine, cyclodextrins primarily act as a complexing vehicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213bbb2c694b6d23adb09545ba21080d
https://doi.org/10.3389/fncel.2017.00355
https://doi.org/10.3389/fncel.2017.00355
Autor:
Nadia M. Atallah, Ankita Thawani, Kristen N. Fantetti, Donna M. Fekete, R. Keith Duncan, Deborah J. Biesemeier, Kirsten Luethy, Ulrike J. Sienknecht, M. Katie Scott, Vidhya Munnamalai, Eric S Traub, Kuhn H. Song
Vertebrate hearing organs manifest cellular asymmetries across the radial axis that underlie afferent versus efferent circuits between the inner ear and the brain. Therefore, understanding the molecular control of patterning across this axis has impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f2a374cc0d9d6e81f0d1a4184605f4
https://europepmc.org/articles/PMC5597980/
https://europepmc.org/articles/PMC5597980/
Autor:
Che Chan, Sandra Hackelberg, Christina M. White, Ryan J. Miller, Long He, Benjamin R. Loomis, Liqian Liu, Josef M. Miller, Samuel J. Tuck, Arjun Rastogi, R. Keith Duncan, Joseph M. Corey, Diane M. Prieskorn
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180427 (2017)
PLoS ONE
PLoS ONE
Impairment of spiral ganglion neurons (SGNs) of the auditory nerve is a major cause for hearing loss occurring independently or in addition to sensory hair cell damage. Unfortunately, mammalian SGNs lack the potential for autonomous regeneration. Ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fa9f3dba62a8d3a38a8a00a1fb48e1
http://europepmc.org/articles/PMC5495534?pdf=render
http://europepmc.org/articles/PMC5495534?pdf=render
Autor:
Chintan Patel, Paul V. Thomas, Candice C. Colby, R. Keith Duncan, Andrew L. Cheng, Lydia Josephs, Liqian Liu
Publikováno v:
Journal of Proteomics. 103:178-193
Biological membranes organize and compartmentalize cell signaling into discrete microdomains, a process that often involves stable, cholesterol-rich platforms that facilitate protein–protein interactions. Polarized cells with distinct apical and ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d49ef48c6c0c3a8614a4168db87304d
https://doi.org/10.1016/j.jprot.2014.03.037
https://doi.org/10.1016/j.jprot.2014.03.037