Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R. Keaney Rathbun"'
Autor:
Qing-Shuo Zhang, Eric Benedetti, Matthew Deater, Kathryn Schubert, Angela Major, Carl Pelz, Soren Impey, Laura Marquez-Loza, R. Keaney Rathbun, Shigeaki Kato, Grover C. Bagby, Markus Grompe
Publikováno v:
Stem Cell Reports, Vol 4, Iss 1, Pp 90-102 (2015)
Summary: Androgens are widely used for treating Fanconi anemia (FA) and other human bone marrow failure syndromes, but their mode of action remains incompletely understood. Aged Fancd2−/− mice were used to assess the therapeutic efficacy of oxyme
Externí odkaz:
https://doaj.org/article/8a6306b4c4804260b2652a1314bac711
Autor:
Grover C. Bagby, Joanna M. Cain, Susan B. Olson, Fabio Cappuccini, Philippe Thuillier, Abdellatif Errami, C. Michael Zwaan, Najim Ameziane, Allen E. Bale, William H. Rodgers, R. Keaney Rathbun, Winifred Keeble, Yumi Torimaru, Yassmine Akkari, Laura E. Hays, Hong Y. Liu, Jane E. Yates, Tanja Pejovic
Supplementary Figure Legends and Tables 1-2 from Cytogenetic Instability in Ovarian Epithelial Cells from Women at Risk of Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996c6a08b85feb03e564f7fbcab5db14
https://doi.org/10.1158/0008-5472.22364933.v1
https://doi.org/10.1158/0008-5472.22364933.v1
Autor:
Grover C. Bagby, Joanna M. Cain, Susan B. Olson, Fabio Cappuccini, Philippe Thuillier, Abdellatif Errami, C. Michael Zwaan, Najim Ameziane, Allen E. Bale, William H. Rodgers, R. Keaney Rathbun, Winifred Keeble, Yumi Torimaru, Yassmine Akkari, Laura E. Hays, Hong Y. Liu, Jane E. Yates, Tanja Pejovic
Supplementary Figure 1 from Cytogenetic Instability in Ovarian Epithelial Cells from Women at Risk of Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b8d90bed09535feaf8db8f2f52ad85
https://doi.org/10.1158/0008-5472.22364942.v1
https://doi.org/10.1158/0008-5472.22364942.v1
Autor:
Grover C. Bagby, Joanna M. Cain, Susan B. Olson, Fabio Cappuccini, Philippe Thuillier, Abdellatif Errami, C. Michael Zwaan, Najim Ameziane, Allen E. Bale, William H. Rodgers, R. Keaney Rathbun, Winifred Keeble, Yumi Torimaru, Yassmine Akkari, Laura E. Hays, Hong Y. Liu, Jane E. Yates, Tanja Pejovic
Fanconi anemia is an inherited cancer predisposition disease characterized by cytogenetic and cellular hypersensitivity to cross-linking agents. Seeking evidence of Fanconi anemia protein dysfunction in women at risk of ovarian cancer, we screened ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abe60f2e94007d5741792bcdda69158
https://doi.org/10.1158/0008-5472.c.6494441
https://doi.org/10.1158/0008-5472.c.6494441
Autor:
Grover C. Bagby, Joanna M. Cain, Susan B. Olson, Fabio Cappuccini, Philippe Thuillier, Abdellatif Errami, C. Michael Zwaan, Najim Ameziane, Allen E. Bale, William H. Rodgers, R. Keaney Rathbun, Winifred Keeble, Yumi Torimaru, Yassmine Akkari, Laura E. Hays, Hong Y. Liu, Jane E. Yates, Tanja Pejovic
Supplementary Figure 2 from Cytogenetic Instability in Ovarian Epithelial Cells from Women at Risk of Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc0d19ab5d625b32c699f073a4fdd54
https://doi.org/10.1158/0008-5472.22364936
https://doi.org/10.1158/0008-5472.22364936
Autor:
Laura E. Hays, Jane E. Yates, Grover C. Bagby, R. Keaney Rathbun, Michael R. Garbati, Winifred Keeble
Publikováno v:
Blood. 122:3197-3205
Hematopoietic stem and progenitor cells with inactivated Fanconi anemia (FA) genes, FANCA and FANCC, are hypersensitive to inflammatory cytokines. One of these, tumor necrosis factor α (TNF-α), is also overproduced by FA mononuclear phagocytes in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3aeaf0b6f635c596b493380c5f3d8e
https://doi.org/10.1182/blood-2013-02-484816
https://doi.org/10.1182/blood-2013-02-484816
Autor:
Jane E. Yates, David C. Anderson, Grover C. Bagby, Scott M. Vanderwerf, Daniela Pilonetto, Christina A. Harrington, Noemi F. Pereira, Winifred Keeble, R. Keaney Rathbun, Ricardo Pasquini, Johanna Svahn, Susan B. Olson, Praveen Anur
Publikováno v:
Blood. 114:5290-5298
Tumor necrosis factor alpha (TNF-α) production is abnormally high in Fanconi anemia (FA) cells and contributes to the hematopoietic defects seen in FA complementation group C–deficient (Fancc−/−) mice. Applying gene expression microarray and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46fbd45ea9758af5c34d0c8fadbd31c
https://doi.org/10.1182/blood-2009-05-222414
https://doi.org/10.1182/blood-2009-05-222414
Autor:
Nathaniel Jillette, Kathy Chin, R. Keaney Rathbun, Muhsen Al-Dhalimy, Anupriya Agarwal, Laura E. Hays, Michael R. Garbati, Grover C. Bagby, Amy E. Hanlon Newell, Susan B. Olson
The Fanconi anemia proteins participate in a canonical pathway that repairs cross-linking agent-induced DNA damage. Cells with inactivated Fanconi anemia genes are universally hypersensitive to such agents. Fanconi anemia-deficient hematopoietic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf6d5b8ff88b3afe1ef9118a91b0fcd
https://europepmc.org/articles/PMC6608044/
https://europepmc.org/articles/PMC6608044/
Autor:
Anuj Mankad, Susan B. Olson, Yassmine Akkari, Markus Grompe, Grover C. Bagby, Barbara Cox, Alan D. D'Andrea, R. Keaney Rathbun, Toshiyasu Taniguchi, Lora Lucas
Publikováno v:
Blood. 107:3084-3090
Monozygotic twin sisters, with nonhematologic symptoms of Fanconi anemia (FA), were discovered to be somatic mosaics for mutations in the FANCA gene. Skin fibroblasts, but not lymphocytes or committed hematopoietic progenitors, were sensitive to DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbfcb572b295099d46ec68b4cd9a8ad
https://doi.org/10.1182/blood-2005-07-2638
https://doi.org/10.1182/blood-2005-07-2638
Autor:
Tracy A. Christianson, R. Keaney Rathbun, Michael O'Dwyer, Winifred Keeble, Gregory R. Faulkner, Grover C. Bagby, Gary Jones
Publikováno v:
Blood. 96:4204-4211
Hematopoietic progenitor cells (HPC) from mice nullizygous at the Fanconi anemia (FA) group C locus and children with Fanconi anemia group C (FA-C) are hypersensitive to interferon-gamma (IFN-γ) and tumor necrosis factor-α. This hypersensitivity re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107fa514d1fc4010820d905a793dff08
https://doi.org/10.1182/blood.v96.13.4204.h8004204_4204_4211
https://doi.org/10.1182/blood.v96.13.4204.h8004204_4204_4211