Zobrazeno 1 - 10
of 1 585
pro vyhledávání: '"R. KAST"'
Autor:
Michael I Dorrell, Heidi R Kast-Woelbern, Ryan T Botts, Stephen A Bravo, Jacob R Tremblay, Sarah Giles, Jessica F Wada, MaryAnn Alexander, Eric Garcia, Gabriel Villegas, Caylor B Booth, Kaitlyn J Purington, Haylie M Everett, Erik N Siles, Michael Wheelock, Jordan A Silva, Bridget M Fortin, Connor A Lowey, Allison L Hale, Troy L Kurz, Jack C Rusing, Dawn M Goral, Paul Thompson, Alec M Johnson, Daniel J Elson, Roujih Tadros, Charisa E Gillette, Carley Coopwood, Amy L Rausch, Jeffrey M Snowbarger
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252233 (2021)
Tumor angiogenesis is critical for the growth and progression of cancer. As such, angiostasis is a treatment modality for cancer with potential utility for multiple types of cancer and fewer side effects. However, clinical success of angiostatic mono
Externí odkaz:
https://doaj.org/article/2bcc474f3f2743d2ae3bcf6edb8e2f29
Autor:
John A. Mohan, Atleigh G. Forden, Emma R. Kast, Bess B. Ward, Jessica A. Lueders-Dumont, Benjamin D. Walther, Daniel M. Sigman
Publikováno v:
Geochimica et Cosmochimica Acta. 316:69-86
The nitrogen isotopes (δ15N) in the organic fraction of accretionary hard part structures, such as fish otoliths, may provide life histories of dietary change. We performed controlled experiments to validate the dynamics of the isotopic signal incor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398fa4f9739afd3421650b8bc913da1d
https://doi.org/10.1016/j.gca.2021.09.030
https://doi.org/10.1016/j.gca.2021.09.030
Autor:
Emma R. Kast, Michael L. Griffiths, Sora L. Kim, Zixuan C. Rao, Kenshu Shimada, Martin A. Becker, Harry M. Maisch, Robert A. Eagle, Chelesia A. Clarke, Allison N. Neumann, Molly E. Karnes, Tina Lüdecke, Jennifer N. Leichliter, Alfredo Martínez-García, Alliya A. Akhtar, Xingchen T. Wang, Gerald H. Haug, Daniel M. Sigman
Publikováno v:
Science advances, vol 8, iss 25
Science Advances
Science Advances, 8 (25)
Science Advances
Science Advances, 8 (25)
Trophic position is a fundamental characteristic of animals, yet it is unknown in many extinct species. In this study, we ground-truth the 15N/14N ratio of enameloid-bound organic matter (δ15NEB) as a trophic level proxy by comparison to dentin coll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cab586831bec8f970fb534665c2f58
https://escholarship.org/uc/item/5wt1z0z9
https://escholarship.org/uc/item/5wt1z0z9
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 1, Pp 2-12 (2002)
During the last three years there have been a plethora of publications on the liver X-activated receptors (LXRα, NR1H3, and LXRβ, NR1H2), the farnesoid X-activated receptor (FXR, NR1H4), and the pregnane X receptor (PXR, NR1I2) and the role these n
Externí odkaz:
https://doaj.org/article/a690b59beafe47ccade2c583181b895c
Autor:
Emma R. Kast, Jennifer Leichliter, Thomas Tütken, Marcus Clauss, Daniela E. Winkler, Alan D. Foreman, Nicolas N. Duprey, Hubert B. Vonhof, Alfredo Martínez-García, Tina Lüdecke, Gerald H. Haug, Daniel M. Sigman
Publikováno v:
Chemical Geology
Nitrogen isotoperatios (δ15N) are a well-established tool for investigating the dietary and trophic behavior of animals in terrestrial and marine food webs. To date, δ15N values in fossils have primarily been measured in collagen extracted from bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1b5650f7bb43cc4e02e7f625001bc5
https://doi.org/10.5167/uzh-196423
https://doi.org/10.5167/uzh-196423
Autor:
Diana M. Shih, Heidi R. Kast-Woelbern, Jack Wong, Yu-Rong Xia, Peter A. Edwards, Aldons J. Lusis
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 2, Pp 384-392 (2006)
Paraoxonase-1 (PON1), an enzyme that metabolizes organophosphate insecticides, is secreted by the liver and transported in the blood complexed to HDL. In humans and mice, low plasma levels of PON1 have also been linked to the development of atheroscl
Externí odkaz:
https://doaj.org/article/9185cf015fe94d64abdeaa15f04fb047
Autor:
Andrew M. Anisfeld, Heidi R. Kast-Woelbern, Hans Lee, Yanqiao Zhang, Florence Y. Lee, Peter A. Edwards
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 3, Pp 458-468 (2005)
Three genes, fibrinogen-α (FBGα), -β, and -γ, encode proteins that make up the mature FBG protein complex. This complex is secreted from the liver and plays a key role in coagulation in response to vascular disruption. We identified all three FBG
Externí odkaz:
https://doaj.org/article/d308df5bda65440aa920c9eb7d2440fe
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 12, Pp 2037-2041 (2002)
Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PL222222222216) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) a
Externí odkaz:
https://doaj.org/article/d284822ada134e6cab5da80089928525
Autor:
Emma R. Kast, Xingchen T. Wang, Alexandra Auderset, Alfredo Martínez-García, Haojia Ren, John A. Higgins, Daniel A. Stolper, Gerald H. Haug, Daniel M. Sigman
Publikováno v:
Science. 364:386-389
Circulation more than temperature Changes in continental configuration and sea level affected the ocean's oxygen levels and the rate of denitrification between 70 and 30 million years ago. That finding by Kast et al. shows a fundamental difference fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feee9185fed5a19690fa39242c80639d
https://doi.org/10.1126/science.aau5784
https://doi.org/10.1126/science.aau5784
Autor:
Mathis P. Hain, François Fripiat, Gerald H. Haug, Alfredo Martínez-García, Daniel M. Sigman, Anja S Studer, P. C. Kemeny, Sarah E. Fawcett, Emma R. Kast
Publikováno v:
Paleoceanography and Paleoclimatology. 33:1453-1471
In the Antarctic Zone of the Southern Ocean, the coupled observations of elevated diatom‐bound 15N/14N (δ15Ndb) and reduced export production during the ice ages indicates more complete nitrate (NO3−) consumption. This evidence points to an ice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a753127e40efcf62448ec5024fcb2b1
https://doi.org/10.1029/2018pa003478
https://doi.org/10.1029/2018pa003478