Zobrazeno 1 - 10 of 115 pro vyhledávání: '"R. K. Salyaev"'
1
Akademický článek
The effect of 'early' proteins E2, E6 and E7 of papillomavirus of high-risk cancerogenous type HPV16 on cancer HeLa cells, inducing tumour growths in mice lungs
Autor: R. K. Salyaev, N. I. Rekoslavskaya
Publikováno v: Acta Biomedica Scientifica, Vol 7, Iss 3, Pp 260-276 (2022)
The goal of investigation was the development of oral therapeutic vaccine against cancer on basis of antigenic regulatory protein HPV16 E2 encoded by the “early” hpv16 E2 gene.The aim. To study tumour growths in mice lungs inoculated with cancer
Externí odkaz: https://doaj.org/article/3836bee2eaee4f07b039ea9ec7ac20a5
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2
Akademický článek
A bioinformatics approach for identifying the probable cause of the cross-interaction of antibodies to the antigenic protein HPV16 L1 with the HPV6 L1 protein
Autor: A. S. Stolbikov, R. K. Salyaev, N. I. Rekoslavskaya
Publikováno v: Вавиловский журнал генетики и селекции, Vol 25, Iss 7, Pp 787-792 (2021)
This paper describes an attempt to analyze, with the aid of bioinformatics resources (programs and databases), the probable cause of the cross-interaction of antibodies against HPV16 L1 with antigenic protein HPV6 L1, which has been revealed in the i
Externí odkaz: https://doaj.org/article/5435fc9dfec842f094559cfb6d622207
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3
Akademický článek
Bioinformatics analysis of putative causes for сross-reactive antibodies interacting with antigens derived from various pathogenic human papillomaviruses
Autor: A. S. Stolbikov, R. K. Salyaev, N. I. Rekoslavskaya
Publikováno v: Инфекция и иммунитет, Vol 10, Iss 4, Pp 695-706 (2020)
Human papillomaviruses (HPVs) belong to highly abundant resulting in sexually transmitted virus infections, and cause cervical cancer holding place 4 among most common cancer types in women. In 2012, there were registered 266,000 death cases and 528,
Externí odkaz: https://doaj.org/article/ba997a15060c45b3aaf3c99fb6b18cb8
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5
Development and testing of procedures for detecting HPV 6 and HPV 16 DNA in water samples
Autor: A. S. Stolbikov, R. K. Salyaev, N. I. Rekoslavskaya
Publikováno v: Proceedings of Universities. Applied Chemistry and Biotechnology. 11:540-548
The present study aims to develop and test procedures for detecting the DNA of dangerous human papillomaviruses (HPV) types 6 and 16 in water samples. The conserved segments of HPV 6 L1 and HPV 16 L1 nucleic acid sequences were studied using bioinfor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8cf591796a605eb16ba67d8111204a4
https://doi.org/10.21285/2227-2925-2021-11-4-540-548
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6
The Use of the Antigenic Protein HPV6 L1 to Induce the Synthesis of Interferon, CD4 and CD8 T Lymphocytes, and Granzyme B in Blood and Splenocytes of Mice in Order to Develop a Broad Vaccine against Anogenital Papillomatoses
Autor: N. I. Rekoslavskaya, R. K. Salyaev
Publikováno v: Doklady Biochemistry and Biophysics. 500:335-340
The antigenic protein HPV6 L1 was synthesized in the plant expression system based on transgenic tomato fruit during the development of an oral vaccine against anogenital papillomaviruses. In experiments on mice immunization, new data on the inductio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::742b8783e9b0e1c03043e7980ac7192b
https://doi.org/10.1134/s160767292105015x
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7
The Synthesis of Main Capsid Protein of Anogenital Type HPV6 L1 in Plant Expression System on the Basis of Tomato Fruits
Autor: R. K. Salyaev, N. I. Rekoslavskaya, A. S. Stolbikov
Publikováno v: Doklady Biochemistry and Biophysics. 498:193-198
The anogenital type HPV6 L1 major capsid protein was synthesized in a plant expression system on the basis of tomato fruits. The content of HPV6 L1 reached 380 μg per 1 mg of total soluble protein of raw fruit mass, which was represented as a single
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3304a186c5073229c205212693f85315
https://doi.org/10.1134/s160767292103008x
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8
Comparative Study on Redox State of Ascorbic Acid and Ascorbate Oxidase Activity in Vacuoles and Leucoplasts of Red Beet Taproots during Physiological Dormancy
Autor: E. V. Pradedova, O. D. Nimaeva, R. K. Salyaev, N. V. Semenova
Publikováno v: Russian Journal of Plant Physiology. 68:74-84
Vacuoles and leucoplasts were isolated from red beet (Beta vulgaris L.) taproots and compared in terms of ascorbic acid concentration and ascorbate oxidase (AO) activity. The total amount of ascorbic acid (AAtot) was greater in vacuoles than in the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79a75f3297fc8e55cdfb50b574eccdb5
https://doi.org/10.1134/s1021443721010143
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9
New Data on the Influence of the HPV16 E2 Early Protein Obtained in Plant Expression Nanosystems on Tumor Tissues of Female Mice Induced by Injection of HeLa Cancer Cells in Hip Muscle
Autor: N. I. Rekoslavskaya, R. K. Salyaev, A. S. Stolbikov
Publikováno v: Nanotechnologies in Russia. 15:516-522
The prospects of creating a therapeutic anti-cancer vaccine using the HPV16 E2 regulatory gene have been investigated. An expression system for the synthesis of early antigenic proteins HPV16 E2, of high-risk papillomavirus based on transgenic tomato
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1a2972cfeb9e557e2eaa2f4a18a0b96
https://doi.org/10.1134/s1995078020040138
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