Zobrazeno 1 - 10
of 36
pro vyhledávání: '"R. K. Sachs"'
Publikováno v:
The British Journal of Radiology. 85:e1166-e1173
Diagnostic medical radiation has been the most rapidly increasing component of population background radiation exposure in Western countries over the past decade. This trend is set to increase as CT scanning is readily available with burgeoning use i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b1618e556e07d454e70870e20f5ef7
https://doi.org/10.1259/bjr/25026140
https://doi.org/10.1259/bjr/25026140
Publikováno v:
Physics in Medicine & Biology. 63:235018
To propose new schemas for radiation boosting of primary tumors, in locally advanced non-small cell lung cancers (NSCLC), in conjunction with standard chemoradiotherapy. To investigate the effect of temporal distributions of the boost fractions on tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438ff86cfbe358f79e41056e993f68c4
https://doi.org/10.1088/1361-6560/aaee24
https://doi.org/10.1088/1361-6560/aaee24
Autor:
B, Liu, R K, Sachs
Publikováno v:
Bulletin of Mathematical Biology. 59:325-337
A polymer model for the overall geometric structure of a human chromosome during the G0/G1 portion of cell-cycle interphase is constructed, based on fluorescence in situ hybridization data on distances between defined genomic sequences. The model con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eff07be6ecdffa822f34c6047e0bd43
https://doi.org/10.1007/bf02462006
https://doi.org/10.1007/bf02462006
Excess acentric fragments, consisting of acentric rings and acentric linear fragments, are among the most frequent kinds of chromosome-type aberrations produced by radiation. The frequency of acentric rings cannot be obtained directly by experiment b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d94b0e8d619f22ad0b14b20d804866
http://hdl.handle.net/11588/504860
http://hdl.handle.net/11588/504860
Publikováno v:
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 17
DSBs (double-strand breaks) produced by densely ionizing space radiation are not located randomly in the genome: recent data indicate DSB clustering along chromosomes. DSB clustering at large scales, from100 Mbp down to approximately 2 kbp, is modele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50e737d4c48e2b296b260f703353e3c8
https://pubmed.ncbi.nlm.nih.gov/11771543
https://pubmed.ncbi.nlm.nih.gov/11771543
Autor:
D J, Brenner, R K, Sachs
Publikováno v:
Radiation research. 154(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e516c73ed0d71490878c5036f7fc98f
https://pubmed.ncbi.nlm.nih.gov/11187023
https://pubmed.ncbi.nlm.nih.gov/11187023
Publikováno v:
Radiation research. 150(1)
One of the fundamental tools in radiation biology is a formalism describing time-dose relationships. For example, there is a need for reliable predictions of radiotherapeutic isoeffect doses when the temporal exposure pattern is changed. The most com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80e30ef60975253624220c2e1864c424
https://pubmed.ncbi.nlm.nih.gov/9650605
https://pubmed.ncbi.nlm.nih.gov/9650605
Autor:
A M, Chen, J N, Lucas, P J, Simpson, C S, Griffin, J R, Savage, D J, Brenner, L R, Hlatky, R K, Sachs
Publikováno v:
Radiation research. 148
With fluorescence in situ hybridization (FISH), many different categories of chromosome aberrations can be recognized-dicentrics, translocations, rings and various complex aberrations such as insertions or three-way interchanges. Relative frequencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ef46aec7700215141e3db0ce4733e1b
https://pubmed.ncbi.nlm.nih.gov/9355862
https://pubmed.ncbi.nlm.nih.gov/9355862
Publikováno v:
Radiation research. 148(4)
Many chromosome-type, exchange-type chromosomal aberrations produced by radiation are intrachanges, i.e. involve only one chromosome. It is assumed such intrachanges are formed by illegitimate reunion of two double-strand breaks (DSBs) on the chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::332e55e781dabaf6dcbe1d9e6848c128
https://pubmed.ncbi.nlm.nih.gov/9339949
https://pubmed.ncbi.nlm.nih.gov/9339949
Publikováno v:
Radiation research. 141(2)
Most chromosome aberrations produced by ionizing radiation develop from DNA double-strand breaks (DSBs). Published data on the yield and variance of excess acentric fragments after in vitro irradiation of human lymphocytes were compared with correspo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38786f1005e464239553d2f909eca671
https://pubmed.ncbi.nlm.nih.gov/7838952
https://pubmed.ncbi.nlm.nih.gov/7838952