Zobrazeno 1 - 10
of 44
pro vyhledávání: '"R. K. Orkand"'
Autor:
R K Orkand, R C Thomas
Publikováno v:
The Journal of Physiology. 489:19-28
1. We have measured cytosolic free Ca2+ concentrations ([Ca2+]i) in voltage-clamped snail neurones using fura-2. Transient increases in [Ca2+]i were induced by depolarizing voltage steps of 20-60 mV for 0.1-10 s from a holding potential of -50 or -60
Publikováno v:
Physiological research. 51(2)
The effect of suramin, an inhibitor of G protein regulated signalling, was studied on the membrane currents induced by noxious heat and by capsaicin in cultured dorsal root ganglia neurones isolated from neonatal rats. Whole-cell responses induced by
Autor:
A, Bringmann, S N, Skatchkov, T, Pannicke, B, Biedermann, H, Wolburg, R K, Orkand, A, Reichenbach
Publikováno v:
Microscopy research and technique. 50(5)
Whereas in the brain, the activity of the neurons is supported by several types of glial cells such as astrocytes, oligodendrocytes, and ependymal cells, the retina (evolving from the brain during ontogenesis) contains only one type of macroglial cel
Autor:
S N, Skatchkov, M J, Eaton, J, Krusek, R W, Veh, B, Biedermann, A, Bringmann, T, Pannicke, R K, Orkand, A, Reichenbach
Publikováno v:
Glia. 31(1)
Previous studies in retinal glial (Müller) cells have suggested that (1) the dominant membrane currents are mediated by K(+) inward-rectifier (Kir) channels (Newman and Reichenbach, Trends Neurosci 19:307-312, 1996), and (2) rectification of these K
Publikováno v:
Glia. 27(2)
Müller (radial glial) cells span the retina from the outer to the inner limiting membranes. They are the only glial cells found in the amphibian retina. The thickness of the frog (Rana pipiens) retina decreases by a factor of about four from the cen
Publikováno v:
The Journal of physiology. 517
1. Membrane currents induced by noxious heat (Iheat) were studied in cultured dorsal root ganglion (DRG) neurones from newborn rats using ramps of increasing temperature of superfusing solutions. 2. Iheat was observed in about 70 % of small (< 25 mic
Autor:
L, Rojas, R K, Orkand
Publikováno v:
Glia. 25(2)
The radial glial cells that span the retina, described by Müller in 1851, have a remarkable distribution of ion channels in adult amphibia that mediate extracellular K+ spatial buffering. 94% of the total membrane conductance of these cells resides
Publikováno v:
Glia. 17(1)
The processes that participate in clearing increases in [K+]o produced by active neurons include KCl uptake, Na pump stimulation, and spatial buffering. The latter process requires glial cells to carry: 1) inward K+ currents in regions where K+ is el
Autor:
H, Marrero, R K, Orkand
Publikováno v:
Glia. 16(3)
Coordinating the activity of neurons and their satellite glial cells requires mechanisms by which glial cells detect neuronal activity and change their properties as a result. This study monitors the intercellular diffusion of the fluorescent dye Luc
Publikováno v:
Journal of neuroscience research. 40(3)
Using the whole-cell patch-clamp technique, the effects of serotonin (5-HT) and increased acidity to produce membrane currents and to modify high threshold voltage-dependent calcium currents were studied in isolated dorsal root ganglion (DRG) cells o