Zobrazeno 1 - 10
of 51
pro vyhledávání: '"R. K. Khar"'
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 7, Iss 3, Pp 195-200 (2015)
Objective: Due to the structure and physiological barrier of eye, only 1% of instilled dose is available for action on the corneal surface. In this work, we developed and evaluated chitosan (pH sensitive) and gellan gum (ion sensitive) in situ gel of
Externí odkaz:
https://doaj.org/article/8296a8c9b6794b8688aae6bcf9c9196a
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 7, Iss 1, Pp 9-14 (2015)
Introduction: Delivering drugs to ocular region is a challenging task. Eye physiological barriers lead to relatively less therapeutic and bioavailability effect by the conventional eye drops. This may be overcome by the use of in situ gel delivery sy
Externí odkaz:
https://doaj.org/article/9a5eb9c3f3a641aa94beb7e05ba96bb8
Publikováno v:
International Journal of Drug Delivery Technology. 7
The phytosome technology was developed by Indena markedly enhancing the bioavailability of selected phytomedicines, by incorporating phospholipids into standardized plant extract, which improve their absorption and utilization. Phytosome are advanced
Publikováno v:
Drug Delivery. 20:306-309
Availability of proper concentration of medicament on to the corneal surface is a challenging task. Many novel formulations, i.e. hydrogels, nanoparticles, ocuserts, etc. had been tested to improve ocular bioavailability, out of which our group found
Publikováno v:
Journal of Pharmacology and Toxicology. 7:64-77
Autor:
Sushama Talegaonkar, Mohammed Aqil, Naseem Akhtar, R. K. Khar, Manu Jaggi, Zeenat Iqbal, Farhan Jalees Ahmad, Abdul Ahad
Publikováno v:
Expert Opinion on Therapeutic Patents. 21:561-576
The ATP-binding cassette superfamily contains membrane transporter proteins that transport a wide range of diverse compounds across cellular membranes. The P-glycoprotein (P-gp) is an important member of this family and a multi-specific drug efflux t
Publikováno v:
Journal of Drug Targeting. 19:409-417
Drug delivery to ocular region is a challenging task. Only 1-2% of drug is available in eye for therapeutic action, rest of the drug is drained out through nasolachrymal drainage system and other ocular physiological barriers. To overcome these probl
Publikováno v:
Research Journal of Pharmacy and Technology. 11:5001
Autor:
Asif Ali, Sohail Akhter, Zeenat Iqbal, R. K. Khar, Farhan Jalees Ahmad, Sanjar Alam, Sushama Talegaonkar
Publikováno v:
Journal of Dispersion Science and Technology. 31:84-94
The objective of our study was to design a novel microemulsion system of broad spectrum antifungal agent Itraconazole for its sustained and prolong action without using an additional permeation enhancer. Pseudoternary phase diagrams were constructed,
Autor:
R. K. Khar, Farhan Jalees Ahmad, Mohammad Rizwan, Mohd. Aqil, Sushama Talegaonkar, Zafar Iqbal, Adnan Azeem
Publikováno v:
Acta Chromatographica. 21:283-297
Summary An accurate, sensitive, precise, rapid and isocratic reversed-phase HPLC (RPHPLC) method for analysis of buspirone in the bulk drug and in solid dosage formulations has been developed and validated. The best separation was achieved on a 250 m