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Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients

Autor: A. Deodhar, Wayne Tsuji, Charles Peterfy, L. Zhou, P Ory, R. Trapp, W. Shergy, J. Schechtman, Richard Newmark, H. Wang, D. Mandel, R. K. Dore, T. Fuerst

Publikováno v: Arthritis Care & Research. 62:569-574

Objective Periarticular osteoporosis is one of the earliest radiographic signs of bone damage in rheumatoid arthritis (RA). Denosumab, an investigational fully human monoclonal antibody that binds to RANKL, inhibits bone erosion and systemic bone los

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fb998dedcc5b4ce57df08e10e6242f
https://doi.org/10.1002/acr.20004

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The immunogenicity, safety, and efficacy of etanercept liquid administered once weekly in patients with rheumatoid arthritis

Autor: R K, Dore, S, Mathews, J, Schechtman, W, Surbeck, D, Mandel, A, Patel, L, Zhou, P, Peloso

Publikováno v: Clinical and experimental rheumatology. 25(1)

To evaluate the immunogenicity, safety, and efficacy of 50 mg/mL liquid etanercept.In a multicenter, open-label study, adults with active rheumatoid arthritis (RA) received 50 mg/mL liquid etanercept subcutaneously once weekly for 24 weeks. Immunogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0e27a9fe04a9c71e06c176353c3b78f
https://pubmed.ncbi.nlm.nih.gov/17417989

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