Zobrazeno 1 - 10
of 786
pro vyhledávání: '"R. Johnstone"'
Autor:
Laura Beth Payne, Hanaa Abdelazim, Maruf Hoque, Audra Barnes, Zuzana Mironovova, Caroline E. Willi, Jordan Darden, Clifton Houk, Meghan W. Sedovy, Scott R. Johnstone, John C. Chappell
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 711 (2023)
The platelet-derived growth factor-BB (PDGF-BB) pathway provides critical regulation of cerebrovascular pericytes, orchestrating their investment and retention within the brain microcirculation. Dysregulated PDGF Receptor-beta (PDGFRβ) signaling can
Externí odkaz:
https://doaj.org/article/18492473d12f44579b92286ed0d3b899
Autor:
D. Ryan King, Meghan W. Sedovy, Xinyan Leng, Jianxiang Xue, Samy Lamouille, Michael Koval, Brant E. Isakson, Scott R. Johnstone
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10186 (2021)
Gap junctions (GJ) and connexins play integral roles in cellular physiology and have been found to be involved in multiple pathophysiological states from cancer to cardiovascular disease. Studies over the last 60 years have demonstrated the utility o
Externí odkaz:
https://doaj.org/article/9ab401de873e408cbf54567e7eac8c4b
Autor:
D. Ryan King, Meghan W. Sedovy, Xinyan Eaton, Luke S. Dunaway, Miranda E. Good, Brant E. Isakson, Scott R. Johnstone
Publikováno v:
Comprehensive Physiology. :3833-3867
The arterial vasculature can be divided into large conduit arteries, intermediate contractile arteries, resistance arteries, arterioles, and capillaries. Resistance arteries and arterioles primarily function to control systemic blood pressure. The re
Autor:
Harry Scott, Li Dong, Andrew Stevenson, Alasdair I. MacDonald, Sharmila Srinivasan, Paola Massimi, Lawrence Banks, Patricia E. Martin, Scott R. Johnstone, Sheila V. Graham
Publikováno v:
Journal of Cell Science.
Gap junction channels, composed of connexins, allow direct cell-to-cell communication. Connexin 43 (Cx43) is widely expressed in tissues, including the epidermis. In a previous study of human papillomavirus-positive cervical epithelial tumour cells,
Autor:
Matthew Norris, Paul R. Johnstone, Steve R. Green, Stephen N. Trolove, Jian Liu, Nathan Arnold, Isabelle Sorensen, Carlo van den Dijssel, Steven Dellow, Gina van der Klei, Peter Wright, Glenn Clark, Mike Cummins, Sarah Bromley, Dirk Wallace
Publikováno v:
New Zealand Journal of Crop and Horticultural Science. 51:274-296
Autor:
Laura Beth Payne, Hanaa Abdelazim, Maruf Hoque, Audra Barnes, Zuzana Mironovova, Caroline E. Willi, Jordan Darden, Clifton Jenkins-Houk, Meghan W. Sedovy, Scott R. Johnstone, John C. Chappell
Publikováno v:
bioRxiv
/SUMMARYThe platelet-derived growth factor-BB (PDGF-BB) pathway provides critical regulation of cerebrovascular pericytes, orchestrating their investment and retention within the brain microcirculation. Dysregulated PDGF Receptor-beta (PDGFRβ) signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4f73a3794dae2dd5dc545551add634
https://europepmc.org/articles/PMC9915746/
https://europepmc.org/articles/PMC9915746/
Autor:
Prathamesh D Tamhane, Brian R McNamara, Helen R Russell, Francoise Combes, Yu Qiu, Alastair C Edge, Roberto Maiolino, Andrew C Fabian, Paul E J Nulsen, R Johnstone, Stefano Carniani
We present XSHOOTER observations with previous ALMA, MUSE and $HST$ observations to study the nature of radio-jet triggered star formation and the interaction of radio jets with the interstellar medium in the brightest cluster galaxy (BCG) in the Abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c550e93e634f623165f84357abc5dda0
https://www.repository.cam.ac.uk/handle/1810/349458
https://www.repository.cam.ac.uk/handle/1810/349458
Autor:
Peng Sun, Li Dong, Alasdair I. MacDonald, Shahrzad Akbari, Michael Edward, Malcolm B. Hodgins, Scott R. Johnstone, Sheila V. Graham
Publikováno v:
Viruses, Vol 7, Iss 10, Pp 5243-5256 (2015)
Human papillomavirus type 16 (HPV16) causes a range of cancers including cervical and head and neck cancers. HPV E6 oncoprotein binds the cell polarity regulator hDlg (human homologue of Drosophila Discs Large). Previously we showed in vitro, and now
Externí odkaz:
https://doaj.org/article/6bbe3dad8df74e00b54f025852508abe
Autor:
Meghan W. Sedovy, Xinyan Leng, Melissa R. Leaf, Farwah Iqbal, Laura Beth Payne, John C. Chappell, Scott R. Johnstone
Connexin 43 (Cx43) is essential to the function of the vasculature. Cx43 proteins form gap junctions that allow for the exchange of ions and molecules between vascular cells to facilitate cell-to-cell signaling and coordinate vasomotor activity. Cx43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdf8f94185cc22c4e493b4a3b3c3150
https://hdl.handle.net/10919/112060
https://hdl.handle.net/10919/112060
Autor:
Xiaobo Wu, David King, Gregory Hoeker, Scott R Johnstone, Robert G Gourdie, Seth Weinberg, Steven Poelzing
Publikováno v:
Circulation Research. 131
Background: The Long-QT Syndrome Type 3 (LQT3) is characterized by action potential duration (APD) prolongation due to cardiac voltage-gated sodium channel (Nav1.5) gain of function. Arrhythmia risk increases with age in LQT3 patients, but it is unkn