Zobrazeno 1 - 10
of 271
pro vyhledávání: '"R. Jenq"'
Autor:
Yiqian Zhang, Jonas Schluter, Lijun Zhang, Xuan Cao, Robert R. Jenq, Hao Feng, Jonathan Haines, Liangliang Zhang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 4088-4107 (2024)
Due to the development of next-generation sequencing technology and an increased appreciation of their role in modulating host immunity and their potential as therapeutic agents, the human microbiome has emerged as a key area of interest in various b
Externí odkaz:
https://doaj.org/article/a0a2d515603e4b33b2a861f4d9a0a69d
Intratumoral microbiome of adenoid cystic carcinomas and comparison with other head and neck cancers
Autor:
Tatiana V. Karpinets, Yoshitsugu Mitani, Chia-Chi Chang, Xiaogang Wu, Xingzhi Song, Ivonne I. Flores, Lauren K. McDaniel, Yasmine M. Hoballah, Fabiana J. Veguilla, Renata Ferrarotto, Lauren E. Colbert, Nadim J. Ajami, Robert R. Jenq, Jianhua Zhang, Andrew P. Futreal, Adel K. El-Naggar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Adenoid cystic carcinoma (ACC) is a rare, usually slow-growing yet aggressive head and neck malignancy. Despite its clinical significance, our understanding of the cellular evolution and microenvironment in ACC remains limited. We investigat
Externí odkaz:
https://doaj.org/article/e1c7c9a7f34347698b377e27634d3bc8
Autor:
Suet-Ying Kwan, Kristyn A. Gonzales, Mohamed A. Jamal, Heather L. Stevenson, Lin Tan, Philip L. Lorenzi, P. Andrew Futreal, Ernest T. Hawk, Joseph B. McCormick, Susan P. Fisher-Hoch, Robert R. Jenq, Laura Beretta
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The gut microbiota drives progression to liver fibrosis, the main determinant of mortality in metabolic dysfunction-associated steatohepatitis (MASH). In this study, we aimed to identify bacterial species associated with protection against liver fibr
Externí odkaz:
https://doaj.org/article/024dc3e0692f4057b109c7aedd234a0a
Autor:
Josaura Fernandez‐Sanchez, Rachel Rodgers, Arushana A. Maknojia, Nusrat Shaikh, Hannah Yan, Marlyd E. Mejia, Hope Hendricks, Robert R. Jenq, Pavan Reddy, Ritu Banerjee, Jeremy M. Schraw, Megan T. Baldridge, Katherine Y. King
Publikováno v:
HemaSphere, Vol 8, Iss 11, Pp n/a-n/a (2024)
Abstract Prolonged antibiotic exposure causes dangerous hematologic side effects, including neutropenia, in up to 34% of patients. Murine studies established a link between the intestinal microbiota and hematopoiesis. To identify factors that predisp
Externí odkaz:
https://doaj.org/article/67b596162edd4377a6058cb3451d7463
Autor:
Aqsa Mohammed, Robert R Jenq
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 593-595 (2024)
Gut microbiota composition has been reported to affect pathogen susceptibility but its specific effects, the underlying mechanisms and the potential influence of the diet remain unexplored. In their recent study, Desai and colleagues (Wolter et al, 2
Externí odkaz:
https://doaj.org/article/d604850439d84050a585317800798cb0
Autor:
Rishika Prasad, Robert R Jenq
Publikováno v:
eLife, Vol 13 (2024)
An enzyme that remodels the cell wall of Enterococcus faecium helps these gut bacteria to divide and generate peptide fragments that enhance the immune response against cancer.
Externí odkaz:
https://doaj.org/article/a94b3950b93e4f51ad06d44256346844
Autor:
Georgios Angelidakis, Roy F. Chemaly, Pranoti V. Sahasrabhojane, Oscar Morado-Aramburo, Ying Jiang, Micah M. Bhatti, Elizabeth Shpall, Chitra Hosing, Preetesh Jain, Kris Michael Mahadeo, Fareed Khawaja, Peter Elhajj, Jennifer A. Wargo, Robert R. Jenq, Nadim J. Ajami, Partow Kebriaei, Ella J. Ariza-Heredia
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1070 (2024)
Patients undergoing immune effector cell therapy (IECT) are at high risk for infections. We assessed seropositivity against pneumococcus, tetanus, and diphtheria in patients before and after IECT and the patients’ response to vaccination. We enroll
Externí odkaz:
https://doaj.org/article/b2bd91b9270a46a1a6315748347f8e51
Autor:
Tatiana V. Karpinets, Xiaogang Wu, Travis Solley, Molly B. El Alam, Travis T. Sims, Kyoko Yoshida-Court, Erica Lynn, Mustapha Ahmed-Kaddar, Greyson Biegert, Jingyan Yue, Xingzhi Song, Huandong Sun, Joseph F. Petrosino, Melissa P. Mezzari, Pablo Okhuysen, Patricia J. Eifel, Anuja Jhingran, Lilie L. Lin, Kathleen M. Schmeler, Lois Ramondetta, Nadim Ajami, Robert R. Jenq, Andrew Futreal, Jianhua Zhang, Ann H. Klopp, Lauren E. Colbert
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Gut microbiome community composition differs between cervical cancer (CC) patients and healthy controls, and increased gut diversity is associated with improved outcomes after treatment. We proposed that functions of specific micr
Externí odkaz:
https://doaj.org/article/0aaae9f1b6404c15b3d264ad029b00a4
Autor:
Stephanie McMahon, Pranoti Sahasrabhojane, Jiwoong Kim, Samantha Franklin, Chia-Chi Chang, Robert R. Jenq, Andrew E. Hillhouse, Samuel A. Shelburne, Jessica Galloway-Peña
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Bloodstream infections (BSIs) pose a significant mortality risk for acute myeloid leukemia (AML) patients. It has been previously reported that intestinal domination (>30% relative abundance [RA] attributed to a single taxon) with the infect
Externí odkaz:
https://doaj.org/article/83a3eef16a8244b9839fab8b986f0cc4
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Background In microbiome data analysis, unsupervised clustering is often used to identify naturally occurring clusters, which can then be assessed for associations with characteristics of interest. In this work, we systematically compared be
Externí odkaz:
https://doaj.org/article/8702cc8f045046ed8db7be0f39458c71