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CELPI: trial protocol for a randomised controlled trial of a Carer End of Life Planning Intervention in people dying with dementia

Publikováno v: BMC Geriatrics, Vol 22, Iss 1, Pp 1-7 (2022)

Abstract Background Dementia is a leading cause of death in developed nations. Despite an often distressing and symptom laden end of life, there are systematic barriers to accessing palliative care in older people dying of dementia. Evidence exists t

Externí odkaz: https://doaj.org/article/3fc6f21311e3434ebe5316f42da8db4d

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Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

Autor: Eun Young Kang, Dane Cheasley, Cecile LePage, Matthew J. Wakefield, Michelle da Cunha Torres, Simone Rowley, Carolina Salazar, Zhongyue Xing, Prue Allan, David D.L. Bowtell, Anne-Marie Mes-Masson, Diane M. Provencher, Kurosh Rahimi, Linda E. Kelemen, Peter A. Fasching, Jennifer A. Doherty, Marc T. Goodman, Ellen L. Goode, Suha Deen, Paul D.P. Pharoah, James D. Brenton, Weiva Sieh, Constantina Mateoiu, Karin Sundfeldt, Linda S. Cook, Nhu D. Le, Michael S. Anglesio, C. Blake Gilks, David G. Huntsman, Catherine J. Kennedy, Nadia Traficante, D. Bowtell, G. Chenevix-Trench, A. Green, P. Webb, A. DeFazio, D. Gertig, N. Traficante, S. Fereday, S. Moore, J. Hung, K. Harrap, T. Sadkowsky, N. Pandeya, M. Malt, A. Mellon, R. Robertson, T. Vanden Bergh, M. Jones, P. Mackenzie, J. Maidens, K. Nattress, Y.E. Chiew, A. Stenlake, H. Sullivan, B. Alexander, P. Ashover, S. Brown, T. Corrish, L. Green, L. Jackman, K. Ferguson, K. Martin, A. Martyn, B. Ranieri, J. White, V. Jayde, P. Mamers, L. Bowes, L. Galletta, D. Giles, J. Hendley, K. Alsop, T. Schmidt, H. Shirley, C. Ball, C. Young, S. Viduka, Hoa Tran, Sanela Bilic, Lydia Glavinas, Julia Brooks, R. Stuart-Harris, F. Kirsten, J. Rutovitz, P. Clingan, A. Glasgow, A. Proietto, S. Braye, G. Otton, J. Shannon, T. Bonaventura, J. Stewart, S. Begbie, M. Friedlander, D. Bell, S. Baron-Hay, A. Ferrier, G. Gard, D. Nevell, N. Pavlakis, S. Valmadre, B. Young, C. Camaris, R. Crouch, L. Edwards, N. Hacker, D. Marsden, G. Robertson, P. Beale, J. Beith, J. Carter, C. Dalrymple, R. Houghton, P. Russell, M. Links, J. Grygiel, J. Hill, A. Brand, K. Byth, R. Jaworski, P. Harnett, R. Sharma, G. Wain, B. Ward, D. Papadimos, A. Crandon, M. Cummings, K. Horwood, A. Obermair, L. Perrin, D. Wyld, J. Nicklin, M. Davy, M.K. Oehler, C. Hall, T. Dodd, T. Healy, K. Pittman, D. Henderson, J. Miller, J. Pierdes, P. Blomfield, D. Challis, R. McIntosh, A. Parker, B. Brown, R. Rome, D. Allen, P. Grant, S. Hyde, R. Laurie, M. Robbie, D. Healy, T. Jobling, T. Manolitsas, J. McNealage, P. Rogers, B. Susil, E. Sumithran, I. Simpson, K. Phillips, D. Rischin, S. Fox, D. Johnson, S. Lade, M. Loughrey, N. O'Callaghan, W. Murray, P. Waring, V. Billson, J. Pyman, D. Neesham, M. Quinn, C. Underhill, R. Bell, L.F. Ng, R. Blum, V. Ganju, I. Hammond, Y. Leung, A. McCartney, M. Buck, I. Haviv, D. Purdie, D. Whiteman, N. Zeps, Anna DeFazio, Scott Kaufmann, Michael Churchman, Charlie Gourley, Andrew N. Stephens, Nicola S. Meagher, Susan J. Ramus, Yoland C. Antill, Ian Campbell, Clare L. Scott, Martin Köbel, Kylie L. Gorringe, Georgina L. Ryland, Prue E. Allan, Kathryn Alsop, Sumitra Ananda, George Au-Yeung, Maret Böhm, Alison Brand, Georgia Chenevix-Trench, Michael Christie, Yoke-Eng Chiew, Rhiannon Dudley, Nicole Fairweather, Sian Fereday, Stephen B. Fox, Neville F. Hacker, Alison M. Hadley, Joy Hendley, Gwo-Yaw Ho, Sally M. Hunter, Tom W. Jobling, Kimberly R. Kalli, Scott H. Kaufmann, Cecile Le Page, Orla M. McNally, Jessica N. McAlpine, Linda Mileshkin, Jan Pyman, Goli Samimi, Ragwha Sharma, Ian G. Campbell

Publikováno v: Mod Pathol
Kang, E Y, Cheasley, D, Lepage, C, Wakefield, M J, Da Cunha Torres, M, Rowley, S, Salazar, C, Xing, Z, Allan, P, Bowtell, D D L, Mes-masson, A, Provencher, D M, Rahimi, K, Kelemen, L E, Fasching, P A, Doherty, J A, Goodman, M T, Goode, E L, Deen, S, Pharoah, P D P, Brenton, J D, Sieh, W, Mateoiu, C, Sundfeldt, K, Cook, L S, Le, N D, Anglesio, M S, Gilks, C B, Huntsman, D G, Kennedy, C J, Traficante, N, Defazio, A, Kaufmann, S, Churchman, M, Gourley, C, Stephens, A N, Meagher, N S, Ramus, S J, Antill, Y C, Campbell, I, Scott, C L, Köbel, M & Gorringe, K L 2020, ' Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses ', Modern Pathology . https://doi.org/10.1038/s41379-020-0618-9

TP53 mutations are implicated in the progression of mucinous borderline tumors (MBOT) to mucinous ovarian carcinomas (MOC). Optimized immunohistochemistry (IHC) for TP53 has been established as a proxy for the TP53 mutation status in other ovarian tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d1dbbb8d0c6aeaf0b4a7b60db78b77
https://doi.org/10.1038/s41379-020-0618-9

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