Zobrazeno 1 - 10
of 111
pro vyhledávání: '"R. Janáky"'
Publikováno v:
Neurochemical Research. 32:1357-1364
Glutathione (gamma-glutamylcysteinylglycine, GSH and oxidized glutathione, GSSG), may function as a neuromodulator at the glutamate receptors and as a neurotransmitter at its own receptors. We studied now the effects of GSH, GSSG, glutathione derivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b08788d9a04c8faff9fdc9cfad706c
https://doi.org/10.1007/s11064-007-9315-z
https://doi.org/10.1007/s11064-007-9315-z
Publikováno v:
Neurochemistry International. 42:1-7
The aim here was to examine the possible roles of adenylyl cyclase- and protein kinase A (PKA)-dependent processes in ionotropic glutamate receptor (iGluR)-mediated neurotransmission using superfused mouse striatal slices and a non-metabolized L-glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b4d315f658e2521c2d80a6bde57d43
https://doi.org/10.1016/s0197-0186(02)00066-9
https://doi.org/10.1016/s0197-0186(02)00066-9
Publikováno v:
Neurochemical Research. 27:389-394
Glutathione (GSH), a general antioxidant and detoxifying compound, is the most abundant thiol-containing peptide in the central nervous system. It has been earlier shown to regulate the functions of glutamate receptors and to possess specific binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25550702e88a8b36ad5f1c4ecc84a69
https://doi.org/10.1023/a:1015599830320
https://doi.org/10.1023/a:1015599830320
Publikováno v:
Neurochemical Research. 26:1217-1224
The cytosolic release of L-glutamate has been held to be responsible for the increase in extracellular glutamate to toxic levels in the brain. The mechanism and regulation of this release was now studied in cerebral cortical and striatal slices with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef9fac8cf2cc7e8d68daba4e514d66b2
https://doi.org/10.1023/a:1013963222332
https://doi.org/10.1023/a:1013963222332
Publikováno v:
Neurochemical Research. 25:1119-1124
The interactions of S-nitrosoglutathione (GSNO) with the ionotropic glutamate receptors were studied on synaptic membranes isolated from the pig cerebral cortex. GSNO displaced the binding of [3H]glutamate, 3-[(R)-2-carboxypiperazin-4-yl][3H]propyl-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d022da3eeb4ea6c7bc47469143ba80
https://doi.org/10.1023/a:1007626230278
https://doi.org/10.1023/a:1007626230278
Publikováno v:
Neurochemical Research. 25:1397-1405
We review here the possible mechanisms of neuronal degeneration caused by L-cysteine, an odd excitotoxin. L-Cysteine lacks the omega carboxyl group required for excitotoxic actions via excitatory amino acid receptors, yet it evokes N-methyl-D-asparta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8f58b542a783d0104be7bbc24db296
https://doi.org/10.1023/a:1007616817499
https://doi.org/10.1023/a:1007616817499
Autor:
Pirjo Saransaari, András Hermann, Christopher A. Shaw, R. Dohovics, V. Varga, R. Janáky, S. S. Oja
Publikováno v:
Neuroscience. 95:617-624
Glutathione (γ-glutamylcysteinylglycine) is a neuromodulator at glutamate receptors, but may also act as a neurotransmitter at sites of its own. The Na + -independent binding of [ 3 H]glutathione to pig cortical synaptic membranes was characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dda688dd3d9c2a1d0f2b167f4f2c55
https://doi.org/10.1016/s0306-4522(99)00442-x
https://doi.org/10.1016/s0306-4522(99)00442-x
Publikováno v:
Neurochemical Research. 23:1085-1091
The effects of glutathione, glutathione sulfonate and S-alkyl derivatives of glutathione on the binding of glutamate and selective ligands of ionotropic N-methyl-D-aspartate (NMDA) and non-NMDA receptors were studied with mouse synaptic membranes. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74d87bab8ec3c554169fb1b50efda3b
https://doi.org/10.1023/a:1020712203611
https://doi.org/10.1023/a:1020712203611
Publikováno v:
Neuroscience Letters. 234:83-86
The involvement of arginyl residues in the binding of ligands to different ionotropic glutamate receptors, to the modulatory glycine site in the N-methyl-D-aspartate (NMDA) receptor and to the NMDA-governed ionophore was assessed with porcine cortica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb34086120ac60faf3abbec33299217b
https://doi.org/10.1016/s0304-3940(97)00638-1
https://doi.org/10.1016/s0304-3940(97)00638-1
Publikováno v:
Neuroscience Letters. 228:127-130
Possible involvement of histidyl residues in the binding of ligands to ionotropic glutamate receptors and to modulatory sites on the N-methyl-D-aspartate (NMDA) receptor was assessed in porcine cortical synaptic plasma membranes after covalent modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97459d920b64567e3f9794395584d088
https://doi.org/10.1016/s0304-3940(97)00387-x
https://doi.org/10.1016/s0304-3940(97)00387-x