New generation NMR bioreactor coupled with high-resolution NMR spectroscopy leads to novel discoveries in Moorella thermoacetica metabolic profiles

Autor: Paul D. Majors, Jesse A. Sears, R. James Ewing, Nancy G. Isern, Andrei V. Liyu, Junfeng Xue, Harlan Knapp, Daniel R. Sisk, Birgitte Kiær Ahring, Jens Asmus Iversen

Publikováno v: Xue, J, Isern, N G, Ewing, R J, Liyu, A V, Sears, J A, Knapp, H, Iversen, J A, Sisk, D R, Ahring, B K & Majors, P D 2014, ' New generation NMR bioreactor coupled with high-resolution NMR spectroscopy leads to novel discoveries in Moorella thermoacetica metabolic profiles ', Applied Microbiology and Biotechnology, vol. 98, no. 19, pp. 8367-8375 . https://doi.org/10.1007/s00253-014-5847-8

An in situ nuclear magnetic resonance (NMR) bioreactor was developed and employed to monitor microbial metabolism under batch growth conditions in real time. We selected Moorella thermoacetica ATCC 49707 as a test case. M. thermoacetica (formerly Clo

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https://doi.org/10.1007/s00253-014-5847-8