Chemoselective reactions of N1-methyl-2-hydroxy-3-methylamino-3-phenylpropanamide with electrophiles. Synthesis of chiral hexahydro-4-pyrimidones and oxazolidines

Autor: C. Hajji, M. L. Testa, E. Zaballos-García, R. J. Zaragozá, J. Server-Carrió, J. Sepúlveda-Arques

Publikováno v: Tetrahedron (Oxf., Online) 58 (2002): 3281–3285.
info:cnr-pdr/source/autori:C. Hajji, M. L. Testa, E. Zaballos-García, R. J. Zaragozá, J. Server-Carrió, J. Sepúlveda-Arques/titolo:Chemoselective reactions of N1-methyl-2-hydroxy-3-methylamino-3-phenylpropanamide with electrophiles. Synthesis of chiral hexahydro-4-pyrimidones and oxazolidines/doi:/rivista:Tetrahedron (Oxf., Online)/anno:2002/pagina_da:3281/pagina_a:3285/intervallo_pagine:3281–3285/volume:58

The reactivity of (2S,3S)-N1-methyl-2-hydroxy-3-methylamino-3-phenylpropanamide 1, containing three nucleophilic centres has been studied against dihaloalkanes and aldehydes. Hexahydro-4-pyrimidones or oxazolidines were obtained chemoselectively. Exp

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https://publications.cnr.it/doc/53344