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pro vyhledávání: '"R. J. Siarey"'
Autor:
R. J. Siarey, Z. Galdzicki
Publikováno v:
Genes, Brain and Behavior. 2:167-178
Mental retardation in Down's syndrome, human trisomy 21, is characterized by developmental delays, language and memory deficits and other cognitive abnormalities. Neurophysiological and functional information is needed to understand the mechanisms of
Autor:
Z, Galdzicki, R J, Siarey
Publikováno v:
Genes, brain, and behavior. 2(3)
Mental retardation in Down's syndrome, human trisomy 21, is characterized by developmental delays, language and memory deficits and other cognitive abnormalities. Neurophysiological and functional information is needed to understand the mechanisms of
The trisomy 16 (Ts16) mouse is an animal model for human trisomy 21 (Down's syndrome). The gene encoding the NR2A subunit of the NMDA receptor has been localized to mouse chromosome 16. In the present study, western blot analysis revealed a 2.5-fold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2edd41f0cb080405d647c05399d9985f
http://hdl.handle.net/11573/144587
http://hdl.handle.net/11573/144587
Publikováno v:
Neurochemical research. 25(4)
myo-Inositol is elevated in the Down syndrome (DS; trisomy 21) brain and may play a role in mental retardation. In the present study, we examined brain regions and peripheral tissues of Ts65Dn mouse, a recently characterized genetic model of DS, for